Journal of biomedicine & biotechnology.
Discontinued
Publisher:
Hindawi Pub. Corp.,. Cairo : Hindawi Pub. Corp. (2006)
Country: United States
Language: English
Start Year:2001 - 2012
Identifiers
| ISSN: | 1110-7251 (Electronic) 1110-7243 (Print) 1110-7243 (Linking) |
| NLM ID: | 101135740 |
| (OCoLC): | 48512954 |
| Coden: | JBBOAJ |
| LCCN: | 2001242209 |
Analysis of horse myostatin gene and identification of single nucleotide polymorphisms in breeds of different morphological types. Myostatin (MSTN) is a negative modulator of muscle mass. We characterized the horse (Equus caballus) MSTN gene and identified and analysed single nucleotide polymorphisms (SNPs) in breeds of different morphological types. Sequencing of coding, untranslated, intronic, and regulatory regions of MSTN gene in 12 horses from 10 breeds revealed seven SNPs: two in the promoter, four in intron 1, and one in intron 2. The SNPs of the promoter (GQ183900:g.26T>C and GQ183900:g.156T>C, the latter located within a conserved TATA-box like motif) were screened in 396 horses from 16 breeds. The g.26C an...
Influence of muscle-tendon wrapping on calculations of joint reaction forces in the equine distal forelimb. The equine distal forelimb is a common location of injuries related to mechanical overload. In this study, a two-dimensional model of the musculoskeletal system of the region was developed and applied to kinematic and kinetic data from walking and trotting horses. The forces in major tendons and joint reaction forces were calculated. The components of the joint reaction forces caused by wrapping of tendons around sesamoid bones were found to be of similar magnitude to the reaction forces between the long bones at each joint. This finding highlighted the importance of taking into account muscle...