Journal of investigative surgery : the official journal of the Academy of Surgical Research.
Publisher:
Taylor & Francis,. [Philadelphia, PA] : Taylor & Francis
Frequency: Eight issues a year, 2019-
Country: United States
Language: English
Author(s):
Academy of Surgical Research (U.S.)
Start Year:1988 -
ISSN:
0894-1939 (Print)
1521-0553 (Electronic)
0894-1939 (Linking)
1521-0553 (Electronic)
0894-1939 (Linking)
Impact Factor
1.9
2022
| NLM ID: | 8809255 |
| (DNLM): | SR0060829(s) |
| (OCoLC): | 15863360 |
| Coden: | JISUE5 |
| LCCN: | sn 87001050 |
| Classification: | W1 JO73D |
Tracing axons of peripheral nerves in rats: a potential technique to study the equine recurrent laryngeal nerve. To study the fascicular anatomy of peripheral nerves, three different groups of retrograde axonal tracers were evaluated: fluorophores, horseradish peroxidase conjugated to subunit B of cholera toxin (CT-HRP), and adeno-associated virus (AAV). The hindlimb nerves in rats served as a model to identify the most efficient tracer in regard to labeling axons within peripheral nerves. The rat's tibial and common peroneal nerves were injected with the different tracers and the sciatic nerve was subsequently examined for evidence of labeled axons. The CT-HRP clearly provided the best results in this r...
Modified carotid artery transposition for repetitive arterial blood gas sampling in large animals. A modified surgical procedure for creation of a carotid loop for repeated percutaneous sampling of arterial blood gas was performed on 8 Holstein heifers and 14 horses. This approach permitted sampling of blood gas via fine-needle aspiration (one to three times daily) and/or catheterization for extended periods. It offers several advantages over previously reported techniques, including greater accessibility, absence of postoperative complications such as hematoma formation, and absence of foreign materials supporting the loop.
Significance of reperfusion injury after venous strangulation obstruction of equine jejunum. Fifteen horses under halothane anesthesia were assigned randomly to three groups of 5 horses each as follows. In group 1, the distal 50% of the small intestine was measured through a ventral midline celiotomy and replaced in the abdomen so that these horses could serve as sham-operated controls. In group 2, the same segment of small intestine was subjected to venous strangulation obstruction (VSO) for 180 min. In group 3, the same segment of small intestine was subjected to VSO for 90 minutes, followed by 90 minutes of reperfusion. Biopsies of small intestine were taken from all horses to asse...
An arthroscopic biopsy procedure for obtaining osteochondral samples from the equine midcarpal joint. An in vivo biopsy technique was developed to harvest cylindrical osteochondral core samples (2 mm diameter x 2 mm depth) from the articular surfaces of radial carpal bones in adult horses for use in osteoarthritis drug kinetic studies. A 25 degree arthroscope was introduced into the midcarpal joint through the dorsolateral surface, and a custom-built motorized core drill was introduced through the dorsomedial surface to create the osteochondral core samples. A total of 24 core samples were sequentially harvested in vivo, and 16 at postmortem, from eight horses on four different occasions withi...
The pony as an animal model for vascular implants. This study evaluated the pony as a potentially suitable model for vascular implant research. Healthy, conditioned ponies were randomly assigned to one of three groups: group I, carotid artery autografts (n = 6); group II, e-PTFE carotid interpositional grafts (n = 5); and group III, e-PTFE carotid interpositional grafts plus aspirin (10 mg/kg) and dipyridamole (3.5 mg/kg) drug administration. It was found that autografts remained patent longest (mean = 396.2 days; grafts were still patent at time of writing) followed by group III grafts (157.5 days), with group II grafts remaining patent for t...
Evaluation of two techniques for large intestinal resection and anastomosis in the horse. Six normal adult horses had large colon resections at the sternal and diaphragmatic flexures. Stainless steel staples were used to close the stumps of the dorsal and ventral colons in all six. Intestinal continuity was restored with a side-to-side anastomosis of the dorsal and ventral colons. Three of these anastomoses were performed with staples, and three with a double inverting suture pattern. After one month, the horses were surgically reevaluated, and the anastomotic sites were examined. There was no significant difference between the stoma sizes in the two groups. No complications were o...