Journal of materials science. Materials in medicine.
Publisher:
Chapman and Hall,. Norwell, MA : Springer (2008)
Frequency: Monthly, 1994-
Country: United States
Language: English
Start Year:1990 -
ISSN:
0957-4530 (Print)
1573-4838 (Electronic)
0957-4530 (Linking)
1573-4838 (Electronic)
0957-4530 (Linking)
Impact Factor
3.7
2022
| NLM ID: | 9013087 |
| (DNLM): | SR0066726(s) |
| (OCoLC): | 21929562 |
| Coden: | JSMMEL |
| LCCN: | 91642022 |
| Classification: | W1 JO748QR |
Design of an electrospun tubular construct combining a mechanical and biological approach to improve tendon repair. Hand tendon injuries represent a major clinical problem and might dramatically diminish a patient's life quality. In this study, a targeted solution for flexor tendon repair was developed by combining a mechanical and biological approach. To this end, a novel acrylate-endcapped urethane-based polymer (AUP) was synthesized and its physico-chemical properties were characterized. Next, tubular repair constructs were developed using electrospinning of the AUP material with incorporated naproxen and hyaluronic acid (i.e. anti-inflammatory and anti-adhesion compounds, respectively), and with a tubul...
Engineered articular cartilage: influence of the scaffold on cell phenotype and proliferation. Articular cartilage defects do not heal. Biodegradable scaffolds have been studied for cartilage engineering in order to implant autologous chondrocytes and help cartilage repair. We tested some new collagen matrices differing in collagen type, origin, structure and methods of extraction and purification, and compared the behavior of human chondrocytes cultured on them. Human chondrocytes were grown for three weeks on four different equine type I collagen matrices, one type I, III porcine collagen matrix and one porcine type II collagen matrix. After 21 days, samples were subjected to histoche...