Journal of neuroscience methods.
Publisher:
Elsevier/North-Holland Biomedical Press.
Frequency: Eighteen no. a year
Country: Netherlands
Language: English
Start Year:1979 -
ISSN:
0165-0270 (Print)
1872-678X (Electronic)
0165-0270 (Linking)
1872-678X (Electronic)
0165-0270 (Linking)
Impact Factor
3
2022
| NLM ID: | 7905558 |
| (DNLM): | J31200000(s) |
| (OCoLC): | 04929303 |
| Coden: | JNMEDT |
| LCCN: | sc 80001297 |
| Classification: | W1 JO795BS |
Cultivation of Schwann cells from fresh and non-fresh adult equine peripheral nerves. Over the past 25 years, acquired equine polyneuropathy (AEP) has emerged as a neurological disease in Scandinavian horses. This condition is characterized by histopathological features including the presence of Schwann cell (SC) inclusions. Cultivated equine SCs would serve as a valuable resource for investigations of factors triggering this Schwannopathy. Ideally, cells should be sampled for cultivation from fresh nerves immediately after death of the animal, however the availability of fresh material is limited, due to the inconsistent case load and the inherent technical and practical chall...
Developing a 3-choice serial reaction time task for examining neural and cognitive function in an equine model. Large animal models of human neurological disorders are advantageous compared to rodent models due to their neuroanatomical complexity, longevity and their ability to be maintained in naturalised environments. Some large animal models spontaneously develop behaviours that closely resemble the symptoms of neural and psychiatric disorders. The horse is an example of this; the domestic form of this species consistently develops spontaneous stereotypic behaviours akin to the compulsive and impulsive behaviours observed in human neurological disorders such as Tourette's syndrome. The ability to non...