Medical hypotheses.
Publisher:
Eden Press.. Eden Press (2002)
Frequency: Monthly
Country: United States
Language: English
Start Year:1975 -
ISSN:
0306-9877 (Print)
1532-2777 (Electronic)
0306-9877 (Linking)
1532-2777 (Electronic)
0306-9877 (Linking)
Impact Factor
4.7
2022
| NLM ID: | 7505668 |
| (DNLM): | M14420000(s) |
| (OCoLC): | 01357097 |
| Coden: | MEHYDY |
| LCCN: | 80641888 |
| Classification: | W1 ME341D |
Elimination of arthritis pain and inflammation for over 2 years with a single 90 min, topical 14% gallium nitrate treatment: case reports and review of actions of gallium III. Arthritis is inflammation in a joint often with joint damage, usually accompanied by pain, swelling and stiffness, resulting from infection, trauma, degenerative changes, metabolic disturbances, autoimmune or other causes. It occurs in various forms, including rheumatoid arthritis, osteoarthritis, bacterial arthritis and gout. Gallium III can inhibit the production of inflammatory cytokines, such as IL-1beta, produced by macrophage-like cells in vitro. A dose-dependent inhibition of IL-1beta and TPA stimulated MMP activity by gallium nitrate at increasing concentrations occurs, demonstrating t...
The Australian paralysis tick may be the missing link in the transmission of Hendra virus from bats to horses to humans. Hendra virus is a new virus of the family Paramyxoviridae. This virus was first detected in Queensland, Australia, in 1994; although, it seems that the virus has infected fruit-eating bats (flying-foxes) for a very long time. At least 2 humans and 15 horses have been killed by this virus since it first emerged as a virus that may infect mammals other than flying-foxes. Hendra virus is thought to have moved from flying-foxes to horses, and then from horses to people. There is a reasonably strong hypothesis for horse-to-human transmission: transmission of virus via nasal discharge, saliva and/or...
Equine laminitis–another hypothesis for pathogenesis. Laminitis is an important condition in horses and ponies, not just because of the seriousness of the clinical signs and systemic changes involved, but because of the potentially poor prognosis and likelihood of recurrence. Laminitis is particularly prevalent in ponies and involves a multiplicity of aetiological factors. Fat ponies and those having previously suffered laminitis were found to be far more intolerant to oral glucose loading (1 g/kg bwt) than normal ponies or Standardbred horses. These ponies also exhibited a far greater response in plasma insulin levels after glucose loading. Insu...