Microbes and infection
Publisher:
Elsevier,
Frequency: Ten issues a year, 2019-
Country: France
Language: English
Author(s):
Institut Pasteur (Paris, France)
Start Year:1999 -
ISSN:
1286-4579 (Print)
1769-714X (Electronic)
1286-4579 (Linking)
1769-714X (Electronic)
1286-4579 (Linking)
Impact Factor
5.8
2022
| NLM ID: | 100883508 |
| (OCoLC): | 40936628 |
| Coden: | MCINFS |
| LCCN: | sn 99050016 |
| Classification: | W1 MI2605 |
Characterization of experimental equine glanders. Considerable advances in understanding of the disease caused by Burkholderia mallei have been made employing a combination of tools including genetic techniques and animal infection models. The development of small animal models has allowed us to assess the role of a number of putative virulence determinants in the pathogenesis of disease due to B. mallei. Due to the difficulties in performing active immunization studies in small animals, and due to the fact that the horse is the target mammalian species for glanders, we have initiated experimental studies on glanders in horses. Intratracheal ...
The molecular basis of Streptococcus equi infection and disease. Streptococcus equi is the aetiological agent of strangles, one of the most prevalent diseases of the horse. The animal suffering and economic burden associated with this disease necessitate effective treatment. Current antibiotic therapy is often ineffective and thus recent attention has focused on vaccine development. A systematic understanding of S. equi virulence, leading to the identification of targets to which protective immunity can be directed, is a prerequisite of the development of such a vaccine. Here, the virulence factors of S. equi are reviewed.
The West Nile virus: its recent emergence in North America. West Nile fever emerged in New York in the summer of 1999 when seven people, several horses and thousands of wild birds died. It was soon established that the human disease and the mortality of birds were related. Continued surveillance detected West Nile virus in mosquitoes, birds, horses, small mammals, bats and humans, and has shown its spread to several northeastern states. These events confirm the establishment of West Nile virus endemically in the United States.