Molecular genetics and genomics : MGG.
Publisher:
Springer-Verlag,
Frequency: Monthly
Country: Germany
Language: English
Start Year:2001 -
ISSN:
1617-4615 (Print)
1617-4623 (Electronic)
1617-4623 (Linking)
1617-4623 (Electronic)
1617-4623 (Linking)
Impact Factor
3.1
2022
| NLM ID: | 101093320 |
| (OCoLC): | 46767139 |
| Classification: | W1 MO195 |
Selection signatures for heat tolerance in Brazilian horse breeds. Since domestication, horse breeds have adapted to their environments and differentiated from one another. This paper uses two methods to detect selection signatures in 23 horse breeds, eight of which are Brazilian (610 animals), both cold-blooded and warm-blooded, from temperate and tropical regions. These animals were genotyped using the GGP Equine BeadChip and we analysed the data by Principal Component Analysis (PCA). The samples were separated into groups based on their geographical area of origin and PCA results studied. The genomic regions under selection were detected by hapFLK and PCAd...
Whole-genome linkage disequilibrium screening for complex traits in horses. The identification of candidate genes for significant traits is crucial. In this study, we developed and tested effective and systematic methods based on linkage disequilibrium (LD) for the identification of candidate regions for genes with Mendelian inheritance and those associated with complex traits. Our approach entailed the combination of primary screening using pooled DNA samples based on DeltaTAC, secondary screening using an individual typing method and tertiary screening using a permutation test based on the differences in the haplotype frequency between two neighbouring microsatellit...