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One health outlook.
Publisher:
BioMed Central Ltd,
Country: England
Language: English
Author(s):
One Health Platform,
Start Year:2019 -
Identifiers
| ISSN: | 2524-4655 (Electronic) 2524-4655 (Linking) |
| NLM ID: | 101769253 |
| (OCoLC): | 1130288537 |
| LCCN: | 2020243252 |
| Classification: | W1 |
Experimental cross-species infection of donkeys with equine hepacivirus and analysis of host immune signatures. The Equine Hepacivirus (EqHV) is an equine-specific and liver-tropic virus belonging to the diverse genus of Hepaciviruses. It was recently found in a large donkey (Equus asinus) cohort with a similar seroprevalence (30%), but lower rate of RNA-positive animals (0.3%) compared to horses. These rare infection events indicate either a lack of adaptation to the new host or a predominantly acute course of infection. Methods: In order to analyze the susceptibility and the course of EqHV infection in donkeys, we inoculated two adult female donkeys and one control horse intravenously with purified Eq...
