Pediatric research.
Publisher:
Karger.. New York : Nature Publishing Group (2012)
Frequency: Monthly
Country: United States
Language: English
Author(s):
American Pediatric Society., Society for Pediatric Research (U.S.), International Pediatric Research Foundation.
Start Year:1967 -
ISSN:
0031-3998 (Print)
1530-0447 (Electronic)
0031-3998 (Linking)
1530-0447 (Electronic)
0031-3998 (Linking)
Impact Factor
3.6
2022
| NLM ID: | 0100714 |
| (DNLM): | P06520000(s) |
| (OCoLC): | 01761994 |
| Coden: | PEREBL |
| LCCN: | sf 80001040 |
| Classification: | W1 PE175 |
Effects of low-dose hydrocortisone therapy on immune function in neonatal horses. Low-dose hydrocortisone (LDHC) therapy modulates inflammatory responses in adults and improves outcomes in some septic adults and neonates, but its immunologic effects have not been evaluated in neonates. The objective of this study was to evaluate effects of LDHC therapy on ex vivo immune function in neonatal horses (foals). We hypothesized that LDHC treatment would dampen proinflammatory responses without impairing neutrophil function. Hydrocortisone (1.3 mg/kg/d i.v.) was administered to foals in a tapering 3.5 d course. Peripheral blood leukocytes were collected from foals before, during, ...
Calcium metabolism in newborn animals: the interrelationship of calcium, magnesium, and inorganic phosphorus in newborn rats, foals, lambs, and calves. The plasma concentrations of calcium, inorganic phosphorus, and magnesium were studied during the early postnatal period in a rodent (rats), in ruminants (lambs and calves), and in foals. Decreases in plasma calcium after birth were observed only in newborn rats and foals. In rats the postnatal fall in plasma calcium level was already evident 1 hr after cesarean section (9.20 mg/100 ml) as opposed to 11.90 mg/100 ml in utero) and reached a nadir within 6 hr (-4.05 mg/100 ml). Newborn foals showed a small decrease in plasma calcium (-0.73/100 ml) 48 hr after birth. In the four species plasma in...