Pigment cell research
Discontinued
Publisher:
Alan R. Liss, Inc.,. Copenhagen : Munksgaard International Publishers
Frequency: Bimonthly
Country: Denmark
Language: English
Author(s):
European Society for Pigment Cell Research., International Pigment Cell Society.
Start Year:1987 - 2007
ISSN:
0893-5785 (Print)
1600-0749 (Electronic)
0893-5785 (Linking)
1600-0749 (Electronic)
0893-5785 (Linking)
Impact Factor
4.3
2022
| NLM ID: | 8800247 |
| (DNLM): | SR0058643(s) |
| (OCoLC): | 15585546 |
| Coden: | PCREEA |
| LCCN: | 2008243255 |
| Classification: | W1 PI24K |
Comparative histopathology of grey-horse-melanoma and human malignant melanoma. Equine melanoma shows striking features particularly with regard to clinical development in grey horses: in contrast to malignant melanoma in humans and in solid coloured horses that are characterized by early onset of metastasis, pigment cell tumours display almost benign clinical features in ageing grey horses. Through evolution, grey horses appear to be in a favourable position in regard to the biological behaviour of melanomas. Yet unknown factors inhibiting or retarding early melanoma metastasis may be responsible for this phenomenon. In this study, immunostaining profiles and histopathol...
Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review. The color of hair, skin, and eyes in animals mainly depends on the quantity, quality, and distribution of the pigment melanin, which occurs in two types: black to brown eumelanin and yellow to reddish pheomelanin. Microanalytical methods to quantify the amounts of eumelanin and pheomelanin in biological materials were developed in 1985. The methods are based on the chemical degradation of eumelanin to pyrrole-2,3,5-tricarboxylic acid and of pheomelanin to aminohydroxyphenylalanine isomers, which can be analyzed and quantitated by high performance liquid chromatography. This review summarizes a...
The study of cutaneous melanomas in Camargue-type gray-skinned horses (2): epidemiological survey. An epidemiological survey was made on cutaneous melanomas occurring in Camargue-type, gray-skinned horses in southern France. The population investigated was composed of 264 horses, which were selected from the Camargue horse stud registry and were allowed to be examined by the owners. The presence of tumors was inspected macroscopically according to the standardized protocols of veterinary medicine specialists, and some tumors were subjected to macroscopic histopathological examination. The results indicated that: 1) the prevalence of melanomas in the overall population was 31.4%; 2) the odds...
The study of cutaneous melanomas in Camargue-type gray-skinned horses (1): clinical-pathological characterization. The clinical and pathological characteristics of cutaneous melanomas occurring in Camargue-type gray-skinned horses are reported. Examination of 83 tumor-bearing horses revealed that the tumors occurred most frequently underneath the tail (93.9%) and at high rates in the peri-anal region (43.0%), the lips (33.0%), and the eyelids (24.0%), but rarely in the vulva (3.8%). Tumorous lesions were characterized by the presence of either hemispheric nodules or large infiltrated plaques, or their combinations. Microscopic examination indicated that tumorous lesions were composed mostly of melanocytes ...
An estimate of melanosome concentration in pigment tissues. Concentration of melanosomes in various tissues has been unknown because of the impracticability of their direct quantification. Using an indirect approach comprising the estimation of melanin both in freeze-dried tissue samples and in isolated melanosomes, we obtained data on the amount of melanosomes in various pigment tissues. The concentrations of melanosomes found in the tissues were relatively high, not only reflecting the dark color of pigment tissues but also explaining their capacity to perform various functions ascribed to the presence of melanin.
Pigment types of various color genotypes of horses. Hair samples of various colors of horses were analyzed for content of both eumelanin and pheomelanin by a procedure using high performance liquid chromatography. The results are in accord with generally accepted genetic hypotheses accounting for the various colors. However, the results support the hypothesis that the chestnut/sorrel group of colors is conditioned by the extension locus, not the brown locus. The results also indicate that the brown locus is a likely contributor to some rare color phenotypes.