Reviews of infectious diseases.
Discontinued
Publisher:
Univ. of Chicago Press.. Chicago Il : University Of Chicago Press
Frequency: Bimonthly
Country: United States
Language: English
Author(s):
Infectious Diseases Society of America.
Start Year:1979 - 1991
Identifiers
| ISSN: | 0162-0886 (Print) 0162-0886 (Linking) |
| NLM ID: | 7905878 |
| (DNLM): | R29090000(s) |
| (OCoLC): | 04098788 |
| Coden: | RINDDG |
| Classification: | W1 RE257DG |
Equine infectious anemia virus: immunopathogenesis and persistence. Equine infectious anemia (EIA) is a chronic, relapsing infectious disease of horses caused by a nononcogenic retrovirus. Virus persists in infected animals for life and can be reliably detected by serologic tests that measure levels of antibody to the major structural protein of the virus. Periodic virus replication in macrophages leads to an immunologically mediated acute disease characterized primarily by severe anemia. Recrudescence of acute EIA is the result of antigenic variation of the surface glycoprotein of EIA virus. The frequency and severity of clinical episodes of EIA decrease in m...