Stem cell reports.
Publisher:
Cell Press,
Country: United States
Language: English
Author(s):
International Society for Stem Cell Research.
Start Year:2013 -
Identifiers
| ISSN: | 2213-6711 (Electronic) 2213-6711 (Linking) |
| NLM ID: | 101611300 |
| (OCoLC): | 851840728 |
| LCCN: | 2013243500 |
Equine-Induced Pluripotent Stem Cells Retain Lineage Commitment Toward Myogenic and Chondrogenic Fates. Induced pluripotent stem cells (iPSCs) hold great potential not only for human but also for veterinary purposes. The equine industry must often deal with health issues concerning muscle and cartilage, where comprehensive regenerative strategies are still missing. In this regard, a still open question is whether equine iPSCs differentiate toward muscle and cartilage, and whether donor cell type influences their differentiation potential. We addressed these questions through an isogenic system of equine iPSCs obtained from myogenic mesoangioblasts (MAB-iPSCs) and chondrogenic mesenchymal stem ce...