Thrombosis research.
Publisher:
Pergamon Press.
Frequency: Twenty four no. a year
Country: United States
Language: English
Start Year:1972 -
ISSN:
0049-3848 (Print)
1879-2472 (Electronic)
0049-3848 (Linking)
1879-2472 (Electronic)
0049-3848 (Linking)
Impact Factor
7.5
2022
| NLM ID: | 0326377 |
| (DNLM): | T09380000(s) |
| (OCoLC): | 00985997 |
| Coden: | THBRAA |
| Classification: | W1 TH94 |
The hemostatic profile of equine ovarian follicular fluid. The coagulation factors VII and X and fibrinogen were detected in equine ovarian follicular fluid. The amounts of fibrinogen and factor X were approximately 40 percent of that found in normal equine plasma while the level of factor VII was lower, at approximately 14 percent. The addition of human recombinant tissue factor caused fibrin formation in the follicular fluid. The thrombin generating activity appears to be confined to the tissue factor pathway since no activity associated with factors VIII:C, IX or IX was detected. Fibrinolytic activity, at higher levels than that found in plasma, wa...
Vitamin K-dependent carboxylase in horse liver, spleen and kidney. The presence of vitamin K-dependent carboxylase is demonstrated in the microsomal fraction of horse liver, spleen and kidney. The carboxylating enzyme systems in the spleen and in the kidney are susceptible to warfarin in a similar way as is carboxylase from the liver. It is concluded, that during the administration of vitamin K-antagonists (anticoagulation therapy) carboxylase in all these tissues is inhibited. Since most probably the majority of the reaction products of spleen and kidney carboxylase are no clotting factors, the inhibition of their production is a side-effect of the anticoagu...