Topic:Myoglobinuria
Myoglobinuria in horses is a condition characterized by the presence of myoglobin in the urine, often resulting from muscle damage. Myoglobin is a protein found in muscle tissue that is released into the bloodstream when muscle fibers are damaged. This condition is most commonly associated with exertional rhabdomyolysis, also known as "tying-up," where muscle breakdown occurs due to intense exercise or metabolic imbalances. The presence of myoglobin in urine can lead to a dark or coffee-colored appearance and may indicate underlying muscle pathology. This page compiles peer-reviewed research studies and scholarly articles that explore the causes, diagnosis, and implications of myoglobinuria in equine health, as well as strategies for management and prevention.
Malignant hyperthermia in a halothane-anesthetized horse. Malignant hyperthermia developed in a 4-year-old Thoroughbred horse following 3 hours and 15 minutes of halothane anesthesia, with supplementary succinylcholine. Clinical signs included fever, sweating, hyperventilation, tachycardia, and decreased blood pressure followed by a rapid increase in blood pressure. Biochemical aberrations included hypocalcemia, hyperkalemia, hyperphosphatemia, myoglobinuria, and high creatine phosphokinase and ornithine carbamyl transferase activities. Treatment consisted initially of surface cooling with cold water, alcohol and ice, IV administration of cooled bala...
An Outbreak of Myoglobinuria in Light Horses. An outbreak of myoglobinuria under unusual circumstances in a group of four horses, together with the events leading up to the diagnosis, is described, and a brief mention of two previously recorded similar cases is made.