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Home / Equine Research Bank / Med Mycol Case Rep / A case of Candida guilliermondii abortion in an Arab mare.
Medical mycology case reports2014; 4; 19-22; doi: 10.1016/j.mmcr.2014.02.003

A case of Candida guilliermondii abortion in an Arab mare.

Abstract: Ascending infections of equine uterus frequently result in placentitis and abortions; most of these infections are bacterial and are less commonly due to fungi. This report describes an abortion case in an Arab mare due to Candida guilliermondii that was diagnosed via cytological, histological, cultural and biomolecular assays. The histological lesions found were severe necrotizing placentitis associated with fetal pneumonia. To our knowledge this is the first case of C. guilliermondii abortion reported in equine species.
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Publication Date: 2014-03-03 PubMed ID: 24707460PubMed Central: PMC3973842DOI: 10.1016/j.mmcr.2014.02.003Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article recounts an observed case where a fungal infection, specifically Candida guilliermondii, led to abortion in an Arab mare. Although bacterial infections leading to placentitis and subsequent abortion are more common, this fungal cause stands to be the first recorded incident of its kind in equines.

Background of the Study

  • Ascending infections of the equine uterus are often the precursor for placentitis and abortions. In most cases, these infections are bacterial. Fungal infections as the cause, though less common, also occur.
  • This study presents a unique observation of a case where an abortion in an Arab mare was instigated by a fungal infection due to Candida guilliermondii, a relatively rare occurrence.

Methods and Diagnosis

  • The diagnosis was reached through a combination of different scientific tests including cytological, histological, cultural, and biomolecular assays.
  • The ensuing histological examination revealed severe necrotizing placentitis, a severe condition in which the placenta becomes necrotic, killing the cells and tissues, leading in turn to complications such as abortion.
  • Additionally, fetal pneumonia was also noticed, which can result from the immune response of the fetus to the fungal infection.

Significance of the Findings

  • A notable aspect of this study is that it reports the first known case of abortion in equine species due to C. guilliermondii. Thus, it marks a significant contribution to the understanding and documentation of fungal pathogens that can lead to equine abortion.
  • The implication of this discovery could be broad-reaching, opening up further investigations into the effects and spread of fungal infections like C. guilliermondii in equines, potentially leading to development of new preventive and treatment strategies.

Cite This Article

APA
Stefanetti V, Marenzoni ML, Lepri E, Coletti M, Casagrande Proietti P, Agnetti F, Crotti S, Pitzurra L, Del Sero A, Passamonti F. (2014). A case of Candida guilliermondii abortion in an Arab mare. Med Mycol Case Rep, 4, 19-22. https://doi.org/10.1016/j.mmcr.2014.02.003

Publication

Medical mycology case reports
ISSN: 2211-7539
NlmUniqueID: 101598259
Country: Netherlands
Language: English
Volume: 4
Pages: 19-22

Researcher Affiliations

Stefanetti, Valentina
  • Centro di Studi del Cavallo Sportivo, Dipartimento di Medicina Veterinaria, Via San Costanzo 4, 06126 Perugia, Italy.
Marenzoni, Maria Luisa
  • Centro di Studi del Cavallo Sportivo, Dipartimento di Medicina Veterinaria, Via San Costanzo 4, 06126 Perugia, Italy.
Lepri, Elvio
  • Centro di Studi del Cavallo Sportivo, Dipartimento di Medicina Veterinaria, Via San Costanzo 4, 06126 Perugia, Italy.
Coletti, Mauro
  • Centro di Studi del Cavallo Sportivo, Dipartimento di Medicina Veterinaria, Via San Costanzo 4, 06126 Perugia, Italy.
Casagrande Proietti, Patrizia
  • Centro di Studi del Cavallo Sportivo, Dipartimento di Medicina Veterinaria, Via San Costanzo 4, 06126 Perugia, Italy.
Agnetti, Francesco
  • Istituto Zooprofilattico Sperimentale Umbria e Marche, Via G. Salvemini 1, 06126 Perugia, Italy.
Crotti, Silvia
  • Istituto Zooprofilattico Sperimentale Umbria e Marche, Via G. Salvemini 1, 06126 Perugia, Italy.
Pitzurra, Lucia
  • Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Ospedale Santa Maria della Misericordia, Piazzale Menghini 1, 06156 Perugia, Italy.
Del Sero, Andrea
  • Doctor of Veterinary Medicine, Freelancer, Italy.
Passamonti, Fabrizio
  • Centro di Studi del Cavallo Sportivo, Dipartimento di Medicina Veterinaria, Via San Costanzo 4, 06126 Perugia, Italy.

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Citations

This article has been cited 3 times.
  1. Seyedmousavi S, Bosco SMG, de Hoog S, Ebel F, Elad D, Gomes RR, Jacobsen ID, Jensen HE, Martel A, Mignon B, Pasmans F, Piecková E, Rodrigues AM, Singh K, Vicente VA, Wibbelt G, Wiederhold NP, Guillot J. Fungal infections in animals: a patchwork of different situations. Med Mycol 2018 Apr 1;56(suppl_1):165-187.
    doi: 10.1093/mmy/myx104pubmed: 29538732google scholar: lookup
  2. Neira-Egea P, Alamar Malvoisin C, de la Cuesta-Torrado M, Bautista-Erler C, Vitale V, Jolly S, Cesarini C. Gastric Candidiasis in Five Horses: A Case Series. Microorganisms 2025 Jul 25;13(8).
    doi: 10.3390/microorganisms13081746pubmed: 40871249google scholar: lookup
  3. Calderón-Hernández A, Castro-Bonilla N, Cob-Delgado M. Chromogenic, Biochemical and Proteomic Identification of Yeast and Yeast-like Microorganisms Isolated from Clinical Samples from Animals of Costa Rica. J Fungi (Basel) 2024 Mar 16;10(3).
    doi: 10.3390/jof10030218pubmed: 38535226google scholar: lookup
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