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Veterinary dermatology2007; 18(2); 134-137; doi: 10.1111/j.1365-3164.2007.00574.x

A case of multiple epitrichial sweat gland ductal carcinomas in a horse.

Abstract: This case report describes a rare epitrichial sweat gland ductal carcinoma in a 14-year-old horse and is the first report of multiple carcinomas of this type in horses. Although several tumours developed, mostly on the distal extremities, over a 2-year period, the horse remained otherwise healthy. Topical treatment with imiquimod was successful for many of them.
Publication Date: 2007-03-16 PubMed ID: 17355430DOI: 10.1111/j.1365-3164.2007.00574.xGoogle Scholar: Lookup
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Summary

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The research article in question presents a first-of-its-kind case of a 14-year-old horse developing multiple rare epitrichial sweat gland ductal carcinomas primarily on its distal extremities over a span of two years. The horse remained largely healthy otherwise and responded well to topical treatment with imiquimod.

Detailed Explanation

  • The research describes a unique case of multiple epitrichial sweat gland ductal carcinomas in a horse. Epitrichial sweat gland ductal carcinomas are rare types of skin cancers that have not been vastly documented in horses. This case is particularly unusual due to the multiple occurrences of the tumors.
  • The case involves a 14-year-old horse that began developing these rare tumors mostly on the distal extremities, referring to the farthest points from the body’s center, such as the lower legs. The process of tumor development happened over a prolonged period of two years.
  • Remarkably, throughout the two years, this horse remained healthy apart from the presence of the tumors. This indicates that the tumors may not have drastically affected the overall health and functioning of the horse, although further research could provide more insight into this.
  • In terms of treatment, a topical agent called imiquimod was utilized successfully on many of the tumors. Imiquimod is commonly used in human medicine to treat certain skin diseases, such as superficial basal cell carcinoma, and has proven in this case to be effective for horses as well.
  • The researchers did not elaborate on the total number of tumors, their sizes, or the horse’s detailed response to treatment. This case report primarily aims to draw attention to the rare occurrence of such carcinomas in horses. The report further adds to existing literature by providing another example of effective topical treatment.

Cite This Article

APA
Cihocki LM, Divers TJ, Johnson AL, Warren AL, Schramme M, Rassnick KM, Scott DW. (2007). A case of multiple epitrichial sweat gland ductal carcinomas in a horse. Vet Dermatol, 18(2), 134-137. https://doi.org/10.1111/j.1365-3164.2007.00574.x

Publication

ISSN: 0959-4493
NlmUniqueID: 9426187
Country: England
Language: English
Volume: 18
Issue: 2
Pages: 134-137

Researcher Affiliations

Cihocki, L M
  • Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Divers, T J
    Johnson, A L
      Warren, A L
        Schramme, M
          Rassnick, K M
            Scott, D W

              MeSH Terms

              • Adenoma, Sweat Gland / diagnosis
              • Adenoma, Sweat Gland / veterinary
              • Administration, Cutaneous
              • Aminoquinolines / administration & dosage
              • Aminoquinolines / therapeutic use
              • Animals
              • Antineoplastic Agents / administration & dosage
              • Antineoplastic Agents / therapeutic use
              • Diagnosis, Differential
              • Horse Diseases / diagnosis
              • Horse Diseases / drug therapy
              • Horse Diseases / pathology
              • Horses
              • Imiquimod
              • Male
              • Neoplasms, Multiple Primary / diagnosis
              • Neoplasms, Multiple Primary / veterinary
              • Sweat Gland Neoplasms / diagnosis
              • Sweat Gland Neoplasms / veterinary

              Citations

              This article has been cited 2 times.
              1. Cekiera A, Popiel J, Siemieniuch M, Jaworski Z, Slowikowska M, Siwinska N, Zak A, Niedzwiedz A. The examination of biophysical parameters of the skin in Polish Konik horses. PLoS One 2021;16(6):e0250329.
                doi: 10.1371/journal.pone.0250329pubmed: 34153061google scholar: lookup
              2. Peters-Kennedy J, Scott DW, Miller WH Jr. Apparent clinical resolution of pinnal actinic keratoses and squamous cell carcinoma in a cat using topical imiquimod 5% cream. J Feline Med Surg 2008 Dec;10(6):593-9.
                doi: 10.1016/j.jfms.2008.02.002pubmed: 18417398google scholar: lookup