A comparative review of vitamin E and associated equine disorders.
- Journal Article
- Review
Summary
The research article is a comparative review of the function of vitamin E and its relation to various disorders in horses, highlighting its crucial role as an antioxidant, influence on gene expression, platelet aggregation inhibition, and plasma membrane stabilization.
Vitamin E Structure, Absorption, and Metabolism
In this study, the researchers provide information about vitamin E’s structure, absorption process, and metabolism. Vitamin E is a primary chain-breaking antioxidant, which indicates its critical role in preventing the cyclic propagation of lipid peroxidation. Lipid peroxidation refers to the oxidative degradation of lipids in the body, a process that can lead to cell damage and various health disorders. Proper understanding of the absorption and metabolism processes of Vitamin E is crucial as these steps influence its functionality within an organism.
Equine Dietary Recommendations
The study also delves into the current recommendations for dietary vitamin E intake for horses. The researchers reference the Nutritional Research Council (NRC) 2007 requirements advising on the amount of vitamin E necessary to maintain a healthy equine system. The nutritional needs of horses largely depict their health and performance, and as vitamin E impacts several vital processes in their bodies, it is paramount that its intake is adequately regulated.
Antioxidants, Exercise, and Vitamin E Supplementation
The relationship between antioxidants, exercise, and the necessity of vitamin E supplementation beyond the recommended NRC 2007 requirements is also discussed. Exercise triggers an increased metabolic rate which can cause oxidative stress in the equine body. Consequently, horses, particularly those in high-performance settings, may require additional vitamin E supplementation to combat this oxidative stress and maintain cellular health.
Vitamin E-Associated Diseases
The focus of the study is on equine diseases associated with a vitamin E deficiency. This emphasis is necessary as understanding the link between such diseases and deficiency could assist in prevention, early detection, and treatment options. Knowing which diseases are likely to occur from a deficiency in vitamin E could motivate better supplementation practices for equine health.
Protein Involvement in Vitamin E Absorption, Transport, and Metabolism
Finally, the study highlights proteins that participate in vitamin E absorption, transport, and metabolism as potential candidates for vitamin E-associated diseases. Understanding the relationships among these proteins, and their individual roles, could guide future research and provide new insights into combatting equine disorders related to vitamin E deficiency.
Cite This Article
Publication
Researcher Affiliations
- Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA. cjfinno@ucdavis.edu
MeSH Terms
- Animals
- Antioxidants / pharmacology
- Horse Diseases / drug therapy
- Horse Diseases / prevention & control
- Horses
- Vitamin E / pharmacology
Citations
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