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A comparison of laryngoplasty and modified partial arytenoidectomy as treatments for laryngeal hemiplegia in exercising horses.
Abstract: To compare upper airway mechanics, arterial blood gases, and tracheal contamination in horses with induced left laryngeal hemiplegia (recurrent laryngeal neuropathy [RLN]) treated by laryngoplasty/vocal cordectomy (LPVC) or modified partial arytenoidectomy (MPA). Methods: Repeated measures under the following conditions: Control, RLN, LPVC, and MPA. Methods: Six horses. Methods: Two trials were conducted under all conditions at 80% and 100% of maximal heart rate (HR(max)). In Trial 1, arterial blood gases, tracheal and pharyngeal pressures, and laryngeal videoendoscopy were recorded. In Trial 2, upper airway pressure and airflow were determined. Tracheobronchial aspirates were performed after exercise to quantify airway contamination. Results: Compared with control, RLN significantly increased inspiratory impedance and worsened exercise-induced hypoxemia. At 80% HR(max), LPVC restored most variables to control values. At 100% HR(max), LPVC improved all variables, but did not restore minute volume, arterial pH, and PaCO(2). At 80% HR(max), MPA restored all variables except bicarbonate to control values. At 100% HR(max), MPA improved all variables, but did not statistically restore minute ventilation or bicarbonate level. Only minor differences were noted between LPVC and MPA. Both resulted in equivalent tracheal contamination. Conclusions: Airway mechanics and arterial blood gas values were not restored to normal after either LPVC or MPA in horses exercising at HR(max). This does not affect ventilation at sub-maximal exercise, but has clinical implications at HR(max). Both procedures diminish normal laryngeal protective mechanisms. Conclusions: At sub-maximal exercise intensities both LPVC and MPA restore airway ventilation to normal. At maximal exercise the superiority of LPVC over MPA is slight.
Publication Date: 2006-10-10 PubMed ID: 17026549DOI: 10.1111/j.1532-950X.2006.00202.xGoogle Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Comparative Study
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The article compares two treatments for laryngeal hemiplegia in horses, laryngoplasty/vocal cordectomy and modified partial arytenoidectomy, mainly focusing on their effects on horses’ upper airway mechanics, arterial blood gases, and tracheal contamination at different heart rates.
Research Methods
- The study was conducted on six horses using repeated measures under control conditions, with recurrent laryngeal neuropathy (RLN), post laryngoplasty/vocal cordectomy (LPVC) treatment, and post modified partial arytenoidectomy (MPA) treatment.
- Two trials were conducted at 80% and 100% of the horses’ maximum heart rates (HRmax).
- In Trial 1, the researchers recorded arterial blood gases, tracheal and pharyngeal pressures, along with laryngeal videoendoscopy.
- In Trial 2, they measured upper airway pressure and airflow. Tracheobronchial aspirates were performed after exercise to quantify airway contamination.
Results and Findings
- When comparing with the control, the RLN significantly increased inspiratory impedance and worsened exercise-induced hypoxemia.
- At 80% HRmax, LPVC treatment restored most variables to control values, whereas at 100% HRmax, it improved all variables but did not restore minute volume, arterial pH, and PaCO2.
- At 80% HRmax, MPA restored all variables except bicarbonate to control values, while at 100% HRmax, MPA improved all variables but did not statistically restore minute ventilation or bicarbonate level.
- Minor differences were noted between LPVC and MPA. Both treatments resulted in equivalent tracheal contamination.
Conclusions
- The study concluded that neither LPVC nor MPA treatments could fully restore airway mechanics and arterial blood gas values in horses exercising at HRmax. This did not affect ventilation at sub-maximal exercise but has clinical implications at HRmax as both procedures diminish normal laryngeal protective mechanisms.
- At sub-maximal exercise intensities both LPVC and MPA can restore airway ventilation to normal levels.
- However, at maximal exercise intensity, the superiority of LPVC over MPA is only slight.
Cite This Article
APA
Radcliffe CH, Woodie JB, Hackett RP, Ainsworth DM, Erb HN, Mitchell LM, Soderholm LV, Ducharme NG.
(2006).
A comparison of laryngoplasty and modified partial arytenoidectomy as treatments for laryngeal hemiplegia in exercising horses.
Vet Surg, 35(7), 643-652.
https://doi.org/10.1111/j.1532-950X.2006.00202.x Publication
Researcher Affiliations
- Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
MeSH Terms
- Animals
- Arytenoid Cartilage / physiology
- Arytenoid Cartilage / surgery
- Blood Gas Analysis / veterinary
- Female
- Heart Rate / physiology
- Hemiplegia / surgery
- Hemiplegia / veterinary
- Horse Diseases / surgery
- Horses
- Laryngectomy / methods
- Laryngectomy / veterinary
- Male
- Physical Conditioning, Animal
- Random Allocation
- Respiration
- Treatment Outcome
- Vocal Cord Paralysis / surgery
- Vocal Cord Paralysis / veterinary
Citations
This article has been cited 3 times.- Brown BN, Siebenlist NJ, Cheetham J, Ducharme NG, Rawlinson JJ, Bonassar LJ. Computed tomography-guided tissue engineering of upper airway cartilage. Tissue Eng Part C Methods 2014 Jun;20(6):506-13.
- Cheetham J, Regner A, Jarvis JC, Priest D, Sanders I, Soderholm LV, Mitchell LM, Ducharme NG. Functional electrical stimulation of intrinsic laryngeal muscles under varying loads in exercising horses. PLoS One 2011;6(8):e24258.
- Tucker ML, Wilson DG, Bergstrom DJ, Carmalt JL. Comparison of treatments for equine laryngeal hemiplegia using computational fluid dynamic analysis in an equine head model. Front Vet Sci 2024;11:1478511.
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