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Frontiers in microbiology2018; 9; 1941; doi: 10.3389/fmicb.2018.01941

A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies.

Abstract: Among all the emerging and re-emerging animal diseases, influenza group is the prototype member associated with severe respiratory infections in wide host species. Wherein, Equine influenza (EI) is the main cause of respiratory illness in equines across globe and is caused by equine influenza A virus (EIV-A) which has impacted the equine industry internationally due to high morbidity and marginal morality. The virus transmits easily by direct contact and inhalation making its spread global and leaving only limited areas untouched. Hitherto reports confirm that this virus crosses the species barriers and found to affect canines and few other animal species (cat and camel). EIV is continuously evolving with changes at the amino acid level wreaking the control program a tedious task. Until now, no natural EI origin infections have been reported explicitly in humans. Recent advances in the diagnostics have led to efficient surveillance and rapid detection of EIV infections at the onset of outbreaks. Incessant surveillance programs will aid in opting a better control strategy for this virus by updating the circulating vaccine strains. Recurrent vaccination failures against this virus due to antigenic drift and shift have been disappointing, however better understanding of the virus pathogenesis would make it easier to design effective vaccines predominantly targeting the conserved epitopes (HA glycoprotein). Additionally, the cold adapted and canarypox vectored vaccines are proving effective in ceasing the severity of disease. Furthermore, better understanding of its genetics and molecular biology will help in estimating the rate of evolution and occurrence of pandemics in future. Here, we highlight the advances occurred in understanding the etiology, epidemiology and pathobiology of EIV and a special focus is on designing and developing effective diagnostics, vaccines and control strategies for mitigating the emerging menace by EIV.
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Publication Date: 2018-09-06 PubMed ID: 30237788PubMed Central: PMC6135912DOI: 10.3389/fmicb.2018.01941Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research provides a comprehensive review on Equine Influenza Virus, its causes, how it spreads, its effects on horses and other animals, advances in identifying and controlling the infection, and further strategies for control and vaccination.

Etiology, Epidemiology, and Pathobiology

  • Equine influenza (EI) is a significant respiratory illness in horses (equines) and is caused by the Equine Influenza A virus (EIV-A). This disease has high levels of morbidity (illness) and relatively lower levels of mortality (death).
  • The virus is easily transmitted through direct contact and inhalation, which contributes to its wide-spread occurrence. Notably, the EI virus has affected canines and few other animal species apart from horses.
  • The continuous evolution of the virus, with changes at the molecular level, makes it difficult to control.
  • No natural EI-origin infections in humans have been explicitly reported to date.

Advances in Diagnostics

  • Technological advancements enable efficient surveillance and rapid detection of EIV infections in outbreak scenarios. Regular surveillance programs can lead to an improved control strategy of this virus by updating the circulating vaccine strains accordingly.

Vaccine Development

  • There have been recurrent vaccination failures against the virus due to antigenic drift and shift—a phenomenon involving changes in the virus that render a vaccine ineffective. Nevertheless, a better understanding of the virus’s pathogenesis may facilitate the design of effective vaccines, targeting the conserved epitopes (a portion of the virus that is recognized by the immune system).
  • Cold-adapted and canarypox vectored vaccines have shown effectiveness in reducing the seriousness of the disease.

Future Strategies

  • A better understanding of the virus’s genetics and molecular biology may help predict the rate of evolution and potential for pandemics in the future. The focus is on continuing to design and develop effective diagnostics, vaccines, and control strategies to mitigate the harm caused by the EI virus.

Cite This Article

APA
Singh RK, Dhama K, Karthik K, Khandia R, Munjal A, Khurana SK, Chakraborty S, Malik YS, Virmani N, Singh R, Tripathi BN, Munir M, van der Kolk JH. (2018). A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies. Front Microbiol, 9, 1941. https://doi.org/10.3389/fmicb.2018.01941

Publication

Frontiers in microbiology
ISSN: 1664-302X
NlmUniqueID: 101548977
Country: Switzerland
Language: English
Volume: 9
Pages: 1941
PII: 1941

Researcher Affiliations

Singh, Raj K
  • ICAR-Indian Veterinary Research Institute, Bareilly, India.
Dhama, Kuldeep
  • Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, India.
Karthik, Kumaragurubaran
  • Central University Laboratory, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India.
Khandia, Rekha
  • Department of Biochemistry and Genetics, Barkatullah University, Bhopal, India.
Munjal, Ashok
  • Department of Biochemistry and Genetics, Barkatullah University, Bhopal, India.
Khurana, Sandip K
  • National Research Centre on Equines, Hisar, India.
Chakraborty, Sandip
  • Department of Veterinary Microbiology, College of Veterinary Sciences and Animal Husbandry, West Tripura, India.
Malik, Yashpal S
  • Division of Biological Standardization, ICAR-Indian Veterinary Research Institute, Bareilly, India.
Virmani, Nitin
  • National Research Centre on Equines, Hisar, India.
Singh, Rajendra
  • Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, India.
Tripathi, Bhupendra N
  • National Research Centre on Equines, Hisar, India.
Munir, Muhammad
  • Division of Biomedical and Life Sciences, Lancaster University, Lancaster, United Kingdom.
van der Kolk, Johannes H
  • Division of Clinical Veterinary Medicine, Swiss Institute for Equine Medicine (ISME), Vetsuisse Faculty, University of Bern and Agroscope, Bern, Switzerland.

References

This article includes 273 references
  1. Aeschbacher S, Santschi E, Gerber V, Stalder HP, Zanoni RG. [Development of a real-time RT-PCR for detection of equine influenza virus].. Schweiz Arch Tierheilkd 2015 Apr;157(4):191-201.
    doi: 10.17236/sat00015pubmed: 26757582google scholar: lookup
  2. Alexander DJ, Brown IH. Recent zoonoses caused by influenza A viruses.. Rev Sci Tech 2000 Apr;19(1):197-225.
    doi: 10.20506/rst.19.1.1220pubmed: 11189716google scholar: lookup
  3. Alvarez AC, Brunck ME, Boyd V, Lai R, Virtue E, Chen W, Bletchly C, Heine HG, Barnard R. A broad spectrum, one-step reverse-transcription PCR amplification of the neuraminidase gene from multiple subtypes of influenza A virus.. Virol J 2008 Jul 9;5:77.
    doi: 10.1186/1743-422X-5-77pmc: PMC2483269pubmed: 18613963google scholar: lookup
  4. Alves Beuttemmüller E, Woodward A, Rash A, Dos Santos Ferraz LE, Fernandes Alfieri A, Alfieri AA, Elton D. Characterisation of the epidemic strain of H3N8 equine influenza virus responsible for outbreaks in South America in 2012.. Virol J 2016 Mar 19;13:45.
    doi: 10.1186/s12985-016-0503-9pmc: PMC4799594pubmed: 26993620google scholar: lookup
  5. Arthur RJ, Suann CJ. Biosecurity and vaccination strategies to minimise the effect of an equine influenza outbreak on racing and breeding.. Aust Vet J 2011 Jul;89 Suppl 1:109-13.
    doi: 10.1111/j.1751-0813.2011.00764.xpubmed: 21711305google scholar: lookup
  6. Ault A, Zajac AM, Kong WP, Gorres JP, Royals M, Wei CJ, Bao S, Yang ZY, Reedy SE, Sturgill TL, Page AE, Donofrio-Newman J, Adams AA, Balasuriya UB, Horohov DW, Chambers TM, Nabel GJ, Rao SS. Immunogenicity and clinical protection against equine influenza by DNA vaccination of ponies.. Vaccine 2012 Jun 6;30(26):3965-74.
    doi: 10.1016/j.vaccine.2012.03.026pmc: PMC3474358pubmed: 22449425google scholar: lookup
  7. Back H, Berndtsson LT, Gröndahl G, Ståhl K, Pringle J, Zohari S. The first reported Florida clade 1 virus in the Nordic countries, isolated from a Swedish outbreak of equine influenza in 2011.. Vet Microbiol 2016 Feb 29;184:1-6.
    doi: 10.1016/j.vetmic.2015.12.010pubmed: 26854337google scholar: lookup
  8. Balasuriya UB. Type A influenza virus detection from horses by real-time RT-PCR and insulated isothermal RT-PCR.. Methods Mol Biol 2014;1161:393-402.
    doi: 10.1007/978-1-4939-0758-8_34pubmed: 24899448google scholar: lookup
  9. Balasuriya UB, Lee PY, Tiwari A, Skillman A, Nam B, Chambers TM, Tsai YL, Ma LJ, Yang PC, Chang HF, Wang HT. Rapid detection of equine influenza virus H3N8 subtype by insulated isothermal RT-PCR (iiRT-PCR) assay using the POCKIT™ Nucleic Acid Analyzer.. J Virol Methods 2014 Oct;207:66-72.
    doi: 10.1016/j.jviromet.2014.06.016pubmed: 24992669google scholar: lookup
  10. Barba M, Daly JM. The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?. Pathogens 2016 Aug 31;5(3).
    doi: 10.3390/pathogens5030057pmc: PMC5039437pubmed: 27589809google scholar: lookup
  11. Barbic L, Madic J, Turk N, Daly J. Vaccine failure caused an outbreak of equine influenza in Croatia.. Vet Microbiol 2009 Jan 1;133(1-2):164-71.
    doi: 10.1016/j.vetmic.2008.06.009pubmed: 18632226google scholar: lookup
  12. Bayry J. Emerging viral diseases of livestock in the developing world.. Indian J Virol 2013 Dec;24(3):291-4.
    doi: 10.1007/s13337-013-0164-xpmc: PMC3832702pubmed: 24426290google scholar: lookup
  13. Baz M, Paskel M, Matsuoka Y, Zengel J, Cheng X, Treanor JJ, Jin H, Subbarao K. A live attenuated equine H3N8 influenza vaccine is highly immunogenic and efficacious in mice and ferrets.. J Virol 2015 Feb;89(3):1652-9.
    doi: 10.1128/JVI.02449-14pmc: PMC4300743pubmed: 25410860google scholar: lookup
  14. Bengtsson KL. Matrix M adjuvant technology. in Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines (Boston, MA: Springer; ), 309–320.
  15. Bera BC, Virmani N, Shanmugasundaram K, Vaid RK, Singh BK, Gulati BR, Anand T, Barua S, Malik P, Singh RK. Genetic Analysis of the Neuraminidase (NA) Gene of Equine Influenza Virus (H3N8) from Epizootic of 2008-2009 in India.. Indian J Virol 2013 Sep;24(2):256-64.
    doi: 10.1007/s13337-013-0137-0pmc: PMC3784901pubmed: 24426284google scholar: lookup
  16. Bernardino PN, Mapes SM, Corbin R, Pusterla N. Pyrosequencing as a fast and reliable tool to determine clade affiliation for equine Influenza A virus.. J Vet Diagn Invest 2016 May 1;28(3):323-326.
    doi: 10.1177/1040638716638123pubmed: 26961323google scholar: lookup
  17. Blecher K, Nasir A, Friedman A. The growing role of nanotechnology in combating infectious disease.. Virulence 2011 Sep-Oct;2(5):395-401.
    doi: 10.4161/viru.2.5.17035pubmed: 21921677google scholar: lookup
  18. Bogerd HP, Skalsky RL, Kennedy EM, Furuse Y, Whisnant AW, Flores O, Schultz KL, Putnam N, Barrows NJ, Sherry B, Scholle F, Garcia-Blanco MA, Griffin DE, Cullen BR. Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs.. J Virol 2014 Jul;88(14):8065-76.
    doi: 10.1128/JVI.00985-14pmc: PMC4097787pubmed: 24807715google scholar: lookup
  19. Bolfa P, Jeon I, Loftis A, Leslie T, Marchi S, Sithole F, Beck C, Lecollinet S, Zientara S, Hans A, Issel CJ. Detection of West Nile Virus and other common equine viruses in three locations from the Leeward Islands, West Indies.. Acta Trop 2017 Oct;174:24-28.
    doi: 10.1016/j.actatropica.2017.06.023pubmed: 28648789google scholar: lookup
  20. Boukharta M, Azlmat S, Elharrak M, Ennaji MM. Multiple alignment comparison of the non-structural genes of three strains of equine influenza viruses (H3N8) isolated in Morocco.. BMC Res Notes 2015 Sep 24;8:471.
    doi: 10.1186/s13104-015-1441-0pmc: PMC4581100pubmed: 26404167google scholar: lookup
  21. Bountouri M, Fragkiadaki E, Ntafis V, Kanellos T, Xylouri E. Phylogenetic and molecular characterization of equine H3N8 influenza viruses from Greece (2003 and 2007): evidence for reassortment between evolutionary lineages.. Virol J 2011 Jul 14;8:350.
    doi: 10.1186/1743-422X-8-350pmc: PMC3158125pubmed: 21756308google scholar: lookup
  22. Breathnach CC, Clark HJ, Clark RC, Olsen CW, Townsend HG, Lunn DP. Immunization with recombinant modified vaccinia Ankara (rMVA) constructs encoding the HA or NP gene protects ponies from equine influenza virus challenge.. Vaccine 2006 Feb 20;24(8):1180-90.
    doi: 10.1016/j.vaccine.2005.08.091pubmed: 16194586google scholar: lookup
  23. Breathnach CC, Rudersdorf R, Lunn DP. Use of recombinant modified vaccinia Ankara viral vectors for equine influenza vaccination.. Vet Immunol Immunopathol 2004 Apr;98(3-4):127-36.
    doi: 10.1016/j.vetimm.2003.11.004pubmed: 15010222google scholar: lookup
  24. Bryans JT, Doll ER, Wilson JC, McCollum WH. Immunization for equine influenza.. J Am Vet Med Assoc 1966 Feb 15;148(4):413-7.
    pubmed: 5950048
  25. Bryant NA, Paillot R, Rash AS, Medcalf E, Montesso F, Ross J, Watson J, Jeggo M, Lewis NS, Newton JR, Elton DM. Comparison of two modern vaccines and previous influenza infection against challenge with an equine influenza virus from the Australian 2007 outbreak.. Vet Res 2010 Mar-Apr;41(2):19.
    doi: 10.1051/vetres/2009067pmc: PMC2790087pubmed: 19863903google scholar: lookup
  26. Bryant NA, Rash AS, Russell CA, Ross J, Cooke A, Bowman S, MacRae S, Lewis NS, Paillot R, Zanoni R, Meier H, Griffiths LA, Daly JM, Tiwari A, Chambers TM, Newton JR, Elton DM. Antigenic and genetic variations in European and North American equine influenza virus strains (H3N8) isolated from 2006 to 2007.. Vet Microbiol 2009 Jul 2;138(1-2):41-52.
    doi: 10.1016/j.vetmic.2009.03.004pubmed: 19346084google scholar: lookup
  27. Bryant NA, Rash AS, Woodward AL, Medcalf E, Helwegen M, Wohlfender F, Cruz F, Herrmann C, Borchers K, Tiwari A, Chambers TM, Newton JR, Mumford JA, Elton DM. Isolation and characterisation of equine influenza viruses (H3N8) from Europe and North America from 2008 to 2009.. Vet Microbiol 2011 Jan 10;147(1-2):19-27.
    doi: 10.1016/j.vetmic.2010.05.040pubmed: 20580170google scholar: lookup
  28. Burashev Y, Strochkov V, Sultankulova K, Orynbayev M, Sansyzbay A, Sandybayev N, Nurabayev S, Savitskaya I, Rock DL, Tulman ER. Complete Genome Sequencing of Two Equine Influenza A(H3N8) Virus Strains Isolated in Kazakhstan.. Genome Announc 2018 Jun 28;6(26).
    doi: 10.1128/genomeA.00574-18pmc: PMC6025920pubmed: 29954896google scholar: lookup
  29. Burnell FJ, Holmes MA, Roiko AH, Lowe JB, Heil GL, White SK, Gray GC. Little evidence of human infection with equine influenza during the 2007 epizootic, Queensland, Australia.. J Clin Virol 2014 Feb;59(2):100-3.
    doi: 10.1016/j.jcv.2013.11.011pubmed: 24360918google scholar: lookup
  30. Chambers TM. Cross-reactivity of existing equine influenza vaccines with a new strain of equine influenza virus from China.. Vet Rec 1992 Oct 24;131(17):388-91.
    doi: 10.1136/vr.131.17.388pubmed: 1333665google scholar: lookup
  31. Chambers TM. A brief introduction to equine influenza and equine influenza viruses.. Methods Mol Biol 2014;1161:365-70.
    pubmed: 24899445doi: 10.1007/978-1-4939-0758-8_31google scholar: lookup
  32. Chambers TM, Balasuriya UBR. Equine influenza virus. in Molecular Detection of Animal Viral Pathogens, ed Liu D. (Boca Raton, FL: CRC Press; ), 383–392.
  33. Chambers TM, Holland RE, Tudor LR, Townsend HG, Cook A, Bogdan J, Lunn DP, Hussey S, Whitaker-Dowling P, Youngner JS, Sebring RW, Penner SJ, Stiegler GL. A new modified live equine influenza virus vaccine: phenotypic stability, restricted spread and efficacy against heterologous virus challenge.. Equine Vet J 2001 Nov;33(7):630-6.
    doi: 10.2746/042516401776249291pubmed: 11770982google scholar: lookup
  34. Chambers TM, Holland RE Jr, Lai ACK. Equine influenza–current veterinary perspectives, part 2. Equine Pract 17, 26–30.
  35. Chambers TM, Quinlivan M, Sturgill T, Cullinane A, Horohov DW, Zamarin D, Arkins S, García-Sastre A, Palese P. Influenza A viruses with truncated NS1 as modified live virus vaccines: pilot studies of safety and efficacy in horses.. Equine Vet J 2009 Jan;41(1):87-92.
    doi: 10.2746/042516408X371937pmc: PMC2878972pubmed: 19301588google scholar: lookup
  36. Chambers TM, Reedy SE. Equine influenza diagnosis: sample collection and transport.. Methods Mol Biol 2014;1161:371-7.
    doi: 10.1007/978-1-4939-0758-8_32pubmed: 24899446google scholar: lookup
  37. Chambers TM, Reedy SE. Equine influenza culture methods.. Methods Mol Biol 2014;1161:403-10.
    doi: 10.1007/978-1-4939-0758-8_35pubmed: 24899449google scholar: lookup
  38. Chambers TM, Reedy SE. Equine influenza serological methods.. Methods Mol Biol 2014;1161:411-22.
    doi: 10.1007/978-1-4939-0758-8_36pubmed: 24899450google scholar: lookup
  39. Chambers TM, Shortridge KF, Li PH, Powell DG, Watkins KL. Rapid diagnosis of equine influenza by the Directigen FLU-A enzyme immunoassay.. Vet Rec 1994 Sep 17;135(12):275-9.
    doi: 10.1136/vr.135.12.275pubmed: 7817505google scholar: lookup
  40. Chien CY, Xu Y, Xiao R, Aramini JM, Sahasrabudhe PV, Krug RM, Montelione GT. Biophysical characterization of the complex between double-stranded RNA and the N-terminal domain of the NS1 protein from influenza A virus: evidence for a novel RNA-binding mode.. Biochemistry 2004 Feb 24;43(7):1950-62.
    doi: 10.1021/bi030176opubmed: 14967035google scholar: lookup
  41. Collins PJ, Vachieri SG, Haire LF, Ogrodowicz RW, Martin SR, Walker PA, Xiong X, Gamblin SJ, Skehel JJ. Recent evolution of equine influenza and the origin of canine influenza.. Proc Natl Acad Sci U S A 2014 Jul 29;111(30):11175-80.
    doi: 10.1073/pnas.1406606111pmc: PMC4121831pubmed: 25024224google scholar: lookup
  42. Cook RF, Sinclair R, Mumford JA. Detection of influenza nucleoprotein antigen in nasal secretions from horses infected with A/equine influenza (H3N8) viruses.. J Virol Methods 1988 May;20(1):1-12.
    doi: 10.1016/0166-0934(88)90034-1pubmed: 2840448google scholar: lookup
  43. Cooke G. Vaccination for equine influenza: the sports regulator's viewpoint.. Equine Vet J 2013 Nov;45(6):770-1.
    doi: 10.1111/evj.12151pubmed: 24117936google scholar: lookup
  44. Couch RB, Douglas RG, Rossen R, Kasel J. Role of secretory antibody in influenza. in The Secretory Immune System (Washington, DC: U.S. Dept. of Public Health; ), 93–112.
  45. Cowled B, Ward MP, Hamilton S, Garner G. The equine influenza epidemic in Australia: spatial and temporal descriptive analyses of a large propagating epidemic.. Prev Vet Med 2009 Nov 1;92(1-2):60-70.
    doi: 10.1016/j.prevetmed.2009.08.006pubmed: 19748691google scholar: lookup
  46. Crawford PC, Dubovi EJ, Castleman WL, Stephenson I, Gibbs EP, Chen L, Smith C, Hill RC, Ferro P, Pompey J, Bright RA, Medina MJ, Johnson CM, Olsen CW, Cox NJ, Klimov AI, Katz JM, Donis RO. Transmission of equine influenza virus to dogs.. Science 2005 Oct 21;310(5747):482-5.
    doi: 10.1126/science.1117950pubmed: 16186182google scholar: lookup
  47. Crispe E, Finlaison DS, Hurt AC, Kirkland PD. Infection of dogs with equine influenza virus: evidence for transmission from horses during the Australian outbreak.. Aust Vet J 2011 Jul;89 Suppl 1:27-8.
    doi: 10.1111/j.1751-0813.2011.00734.xpubmed: 21711279google scholar: lookup
  48. Crouch CF, Daly J, Hannant D, Wilkins J, Francis MJ. Immune responses and protective efficacy in ponies immunised with an equine influenza ISCOM vaccine containing an 'American lineage' H3N8 virus.. Vaccine 2004 Dec 2;23(3):418-25.
    doi: 10.1016/j.vaccine.2004.01.074pubmed: 15530689google scholar: lookup
  49. Crouch CF, Daly J, Henley W, Hannant D, Wilkins J, Francis MJ. The use of a systemic prime/mucosal boost strategy with an equine influenza ISCOM vaccine to induce protective immunity in horses.. Vet Immunol Immunopathol 2005 Dec 15;108(3-4):345-55.
    doi: 10.1016/j.vetimm.2005.06.009pubmed: 16098611google scholar: lookup
  50. Cullinane A, Elton D, Mumford J. Equine influenza - surveillance and control.. Influenza Other Respir Viruses 2010 Nov;4(6):339-44.
    doi: 10.1111/j.1750-2659.2010.00176.xpmc: PMC4634605pubmed: 20958927google scholar: lookup
  51. Cullinane A, Newton JR. Equine influenza--a global perspective.. Vet Microbiol 2013 Nov 29;167(1-2):205-14.
    doi: 10.1016/j.vetmic.2013.03.029pubmed: 23680107google scholar: lookup
  52. Cullinane AA, Barr B, Bernard W, Duncan JL, Mulcahy G, Smith M. Infectious diseases (chapter 1): equine influenza. in The Equine Manual. 2nd Edn, eds Higgins AJ, Snyder JR (Philadelphia, PA: Elsevier Saunders; ), 13–18.
  53. Daly JM, Blunden AS, Macrae S, Miller J, Bowman SJ, Kolodziejek J, Nowotny N, Smith KC. Transmission of equine influenza virus to English foxhounds.. Emerg Infect Dis 2008 Mar;14(3):461-4.
    doi: 10.3201/eid1403.070643pmc: PMC2570814pubmed: 18325262google scholar: lookup
  54. Daly JM, Lai AC, Binns MM, Chambers TM, Barrandeguy M, Mumford JA. Antigenic and genetic evolution of equine H3N8 influenza A viruses.. J Gen Virol 1996 Apr;77 ( Pt 4):661-71.
    doi: 10.1099/0022-1317-77-4-661pubmed: 8627254google scholar: lookup
  55. Daly JM, MacRae S, Newton JR, Wattrang E, Elton DM. Equine influenza: a review of an unpredictable virus.. Vet J 2011 Jul;189(1):7-14.
    doi: 10.1016/j.tvjl.2010.06.026pubmed: 20685140google scholar: lookup
  56. Daly JM, Murcia PR. Strategic implementation of vaccines for control of equine influenza.. Equine Vet J 2018 Mar;50(2):153-154.
    doi: 10.1111/evj.12794pubmed: 29392805google scholar: lookup
  57. Daly JM, Newton JR, Mumford JA. Current perspectives on control of equine influenza.. Vet Res 2004 Jul-Aug;35(4):411-23.
    doi: 10.1051/vetres:2004023pubmed: 15236674google scholar: lookup
  58. Daly JM, Whitwell KE, Miller J, Dowd G, Cardwell JM, Smith KC. Investigation of equine influenza cases exhibiting neurological disease: coincidence or association?. J Comp Pathol 2006 Feb-Apr;134(2-3):231-5.
    doi: 10.1016/j.jcpa.2005.09.001pubmed: 16527298google scholar: lookup
  59. Damiani AM, Scicluna MT, Ciabatti I, Cardeti G, Sala M, Vulcano G, Cordioli P, Martella V, Amaddeo D, Autorino GL. Genetic characterization of equine influenza viruses isolated in Italy between 1999 and 2005.. Virus Res 2008 Jan;131(1):100-5.
    doi: 10.1016/j.virusres.2007.08.001pubmed: 17889395google scholar: lookup
  60. Dhama K, Chakraborty S, Tiwari R, Verma AK, Saminathan M, Amarpal. A concept paper on novel technologies boosting production and safeguarding health of humans and animals. Res Opin Anim Vet Sci 4, 353–370.
  61. Dhama K, Chakraborty S, Mahima, Wani MY, Verma AK, Deb R, Tiwari R, Kapoor S. Novel and emerging therapies safeguarding health of humans and their companion animals: a review.. Pak J Biol Sci 2013 Feb 1;16(3):101-11.
    doi: 10.3923/pjbs.2013.101.111pubmed: 24171271google scholar: lookup
  62. Dhama K, Karthik K, Khandia R, Munjal A, Tiwari R, Rana R, Khurana SK, Sana Ullah, Khan RU, Alagawany M, Farag MR, Dadar M, Joshi SK. Medicinal and Therapeutic Potential of Herbs and Plant Metabolites / Extracts Countering Viral Pathogens - Current Knowledge and Future Prospects.. Curr Drug Metab 2018;19(3):236-263.
    doi: 10.2174/1389200219666180129145252pubmed: 29380697google scholar: lookup
  63. Dhama K, Mahendran M, Gupta PK, Rai A. DNA vaccines and their applications in veterinary practice: current perspectives.. Vet Res Commun 2008 Jun;32(5):341-56.
    doi: 10.1007/s11259-008-9040-3pmc: PMC7089108pubmed: 18425596google scholar: lookup
  64. Diallo I, Read AJ, Kirkland PD. Positive results in a real-time PCR for type A influenza associated with the use of an inactivated vaccine.. Aust Vet J 2011 Jul;89 Suppl 1:145-6.
    doi: 10.1111/j.1751-0813.2011.00746.xpubmed: 21711315google scholar: lookup
  65. Diaz-Mendez A, Viel L, Hewson J, Doig P, Carman S, Chambers T, Tiwari A, Dewey C. Surveillance of equine respiratory viruses in Ontario.. Can J Vet Res 2010 Oct;74(4):271-8.
    pmc: PMC2949340pubmed: 21197227
  66. Dominguez M, Münstermann S, Murray G, Timoney P. 'High-health, high-performance' horses: risk mitigation strategies for OIE-listed diseases.. Rev Sci Tech 2015 Dec;34(3):837-48.
    doi: 10.20506/rst.34.3.2399pubmed: 27044155google scholar: lookup
  67. Donofrio JC, Coonrod JD, Chambers TM. Diagnosis of equine influenza by the polymerase chain reaction.. J Vet Diagn Invest 1994 Jan;6(1):39-43.
    doi: 10.1177/104063879400600108pubmed: 8011780google scholar: lookup
  68. Easterday BC, Hinshaw VS, Halvorson DA. Influenza. in Diseases of Poultry, 10th Edn., eds. Calnek BW, Barnes HJ, Beard CW, McDougald LR, Saif YM (London: Mosby-Wolfe), 583–605.
  69. Edelman R. An overview of adjuvant use. in Vaccine Adjuvants: Preparation Methods and Research Protocols, Vol. 42 (Totowa, NJ: Humana Press Inc.), 1–27.
  70. Elbadry MA, Merrill MM, Ma MM, Ma MJ, Lu JH, Cao WC, Gray GC. China's great wall, Israel's Bar Lev Line, and passive infectious disease surveillance.. Mil Med Res 2014;1:15.
    doi: 10.1186/2054-9369-1-15pmc: PMC4340838pubmed: 25722872google scholar: lookup
  71. Elton D, Bruce EA, Bryant N, Wise HM, MacRae S, Rash A, Smith N, Turnbull ML, Medcalf L, Daly JM, Digard P. The genetics of virus particle shape in equine influenza A virus.. Influenza Other Respir Viruses 2013 Dec;7 Suppl 4(Suppl 4):81-9.
    doi: 10.1111/irv.12197pmc: PMC5655883pubmed: 24224823google scholar: lookup
  72. Elton D, Bryant N. Facing the threat of equine influenza.. Equine Vet J 2011 May;43(3):250-8.
    doi: 10.1111/j.2042-3306.2010.00357.xpubmed: 21492200google scholar: lookup
  73. Elton D, Cullinane A. Equine influenza: antigenic drift and implications for vaccines.. Equine Vet J 2013 Nov;45(6):768-9.
    doi: 10.1111/evj.12148pubmed: 24117935google scholar: lookup
  74. Favaro PF, Fernandes WR, Reischak D, Brandão PE, Silva SOS, Richtzenhain LJ. Evolution of equine influenza viruses (H3N8) during a Brazilian outbreak, 2015.. Braz J Microbiol 2018 Apr-Jun;49(2):336-346.
    doi: 10.1016/j.bjm.2017.07.003pmc: PMC5913825pubmed: 29100932google scholar: lookup
  75. Feng KH, Gonzalez G, Deng L, Yu H, Tse VL, Huang L, Huang K, Wasik BR, Zhou B, Wentworth DE, Holmes EC, Chen X, Varki A, Murcia PR, Parrish CR. Equine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic Divergence.. J Virol 2015 Jul;89(13):6860-73.
    doi: 10.1128/JVI.00521-15pmc: PMC4468500pubmed: 25903329google scholar: lookup
  76. Feng KH, Sun M, Iketani S, Holmes EC, Parrish CR. Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression.. Virology 2016 Sep;496:138-146.
    doi: 10.1016/j.virol.2016.06.001pmc: PMC4969160pubmed: 27314620google scholar: lookup
  77. Ferguson L, Olivier AK, Genova S, Epperson WB, Smith DR, Schneider L, Barton K, McCuan K, Webby RJ, Wan XF. Pathogenesis of Influenza D Virus in Cattle.. J Virol 2016 Jun 15;90(12):5636-5642.
    doi: 10.1128/JVI.03122-15pmc: PMC4886773pubmed: 27030270google scholar: lookup
  78. Foord AJ, Selleck P, Colling A, Klippel J, Middleton D, Heine HG. Real-time RT-PCR for detection of equine influenza and evaluation using samples from horses infected with A/equine/Sydney/2007 (H3N8).. Vet Microbiol 2009 May 28;137(1-2):1-9.
    doi: 10.1016/j.vetmic.2008.12.006pubmed: 19153018google scholar: lookup
  79. Fougerolle S, Legrand L, Garrett D, Birand I, Foursin M, D'Ablon X, Bayssat P, Newton RJ, Pronost S, Paillot R. Influential factors inducing suboptimal humoral response to vector-based influenza immunisation in Thoroughbred foals.. Vaccine 2016 Jul 19;34(33):3787-95.
    doi: 10.1016/j.vaccine.2016.05.068pubmed: 27269055google scholar: lookup
  80. Fougerolle S, Legrand L, Lecouturier F, Sailleau C, Paillot R, Hans A, Pronost S. Genetic evolution of equine influenza virus strains (H3N8) isolated in France from 1967 to 2015 and the implications of several potential pathogenic factors.. Virology 2017 May;505:210-217.
    doi: 10.1016/j.virol.2017.02.003pubmed: 28292661google scholar: lookup
  81. Frazer JL, Perkins NR, Pitt D. Role of personal decontamination in preventing the spread of equine influenza.. Aust Vet J 2011 Jul;89 Suppl 1:120-4.
    doi: 10.1111/j.1751-0813.2011.00763.xpubmed: 21711308google scholar: lookup
  82. Gahan J, Garvey M, Gildea S, Gür E, Kagankaya A, Cullinane A. Whole-genome sequencing and antigenic analysis of the first equine influenza virus identified in Turkey.. Influenza Other Respir Viruses 2018 May;12(3):374-382.
    doi: 10.1111/irv.12485pmc: PMC5907808pubmed: 28940727google scholar: lookup
  83. Gaíva e Silva L, Borges AM, Villalobos EM, Lara Mdo C, Cunha EM, de Oliveira AC, Braga IA, Aguiar DM. Prevalence of antibodies against influenza virus in non-vaccinated equines from the Brazilian Pantanal.. Rev Inst Med Trop Sao Paulo 2014 Nov-Dec;56(6):487-92.
    doi: 10.1590/S0036-46652014000600006pmc: PMC4296868pubmed: 25351542google scholar: lookup
  84. Galvin P, Gildea S, Arkins S, Walsh C, Cullinane A. The evaluation of a nucleoprotein ELISA for the detection of equine influenza antibodies and the differentiation of infected from vaccinated horses (DIVA).. Influenza Other Respir Viruses 2013 Dec;7 Suppl 4(Suppl 4):73-80.
    doi: 10.1111/irv.12195pmc: PMC5655885pubmed: 24224822google scholar: lookup
  85. Galvin P, Gildea S, Nelly M, Quinlivan M, Arkins S, Walsh C, Cullinane A. The evaluation of three diagnostic tests for the detection of equine influenza nucleoprotein in nasal swabs.. Influenza Other Respir Viruses 2014 May;8(3):376-83.
    doi: 10.1111/irv.12235pmc: PMC4181487pubmed: 24512560google scholar: lookup
  86. Gamoh K, Nakamura S. Update of inactivated equine influenza vaccine strain in Japan.. J Vet Med Sci 2017 Mar 23;79(3):649-653.
    doi: 10.1292/jvms.16-0558pmc: PMC5383192pubmed: 28163276google scholar: lookup
  87. Garrett D, Montesso F, Fougerolle S, Lopez-Alvarez MR, Birand I, De Bock M, Huang CM, Legrand L, Pronost S, Paillot R. Refinement of the equine influenza model in the natural host: A meta-analysis to determine the benefits of individual nebulisation for experimental infection and vaccine evaluation in the face of decreased strain pathogenicity.. Vet Microbiol 2017 Nov;211:150-159.
    doi: 10.1016/j.vetmic.2017.10.010pubmed: 29102112google scholar: lookup
  88. Gerber H. Clinical features, sequelae and epidemiology of equine influenza. in Proceedings of the 2nd International Conference on Equine Infectious Diseases, Paris, 1969, New York, 1970, ed Bryans JT (Basel: Karger; ), 63–80.
  89. Gibbs EP, Anderson TC. Equine and canine influenza: a review of current events.. Anim Health Res Rev 2010 Jun;11(1):43-51.
    doi: 10.1017/S1466252310000046pubmed: 20426896google scholar: lookup
  90. Gildea S, Arkins S, Cullinane A. A comparative antibody study of the potential susceptibility of Thoroughbred and non-Thoroughbred horse populations in Ireland to equine influenza virus.. Influenza Other Respir Viruses 2010 Nov;4(6):363-72.
    doi: 10.1111/j.1750-2659.2010.00163.xpmc: PMC4634612pubmed: 20958930google scholar: lookup
  91. Gildea S, Arkins S, Cullinane A. Management and environmental factors involved in equine influenza outbreaks in Ireland 2007-2010.. Equine Vet J 2011 Sep;43(5):608-17.
    doi: 10.1111/j.2042-3306.2010.00333.xpubmed: 21496094google scholar: lookup
  92. Gildea S, Garvey M, Lyons P, Lyons R, Gahan J, Walsh C, Cullinane A. Multifocal Equine Influenza Outbreak with Vaccination Breakdown in Thoroughbred Racehorses.. Pathogens 2018 Apr 17;7(2).
    doi: 10.3390/pathogens7020043pmc: PMC6027538pubmed: 29673169google scholar: lookup
  93. Gildea S, Quinlivan M, Arkins S, Cullinane A. The molecular epidemiology of equine influenza in Ireland from 2007-2010 and its international significance.. Equine Vet J 2012 Jul;44(4):387-92.
    doi: 10.1111/j.2042-3306.2011.00472.xpubmed: 21978127google scholar: lookup
  94. Gildea S, Sanchez Higgins MJ, Johnson G, Walsh C, Cullinane A. Concurrent vaccination against equine influenza and equine herpesvirus - a practical approach.. Influenza Other Respir Viruses 2016 Sep;10(5):433-7.
    doi: 10.1111/irv.12396pmc: PMC4947937pubmed: 27169603google scholar: lookup
  95. Gonzalez G, Marshall JF, Morrell J, Robb D, McCauley JW, Perez DR, Parrish CR, Murcia PR. Infection and pathogenesis of canine, equine, and human influenza viruses in canine tracheas.. J Virol 2014 Aug;88(16):9208-19.
    doi: 10.1128/JVI.00887-14pmc: PMC4136294pubmed: 24899186google scholar: lookup
  96. Gora IM, Kwasnik M, Zmudzinski JF, Rozek W. Chorioallantoic membranes of embryonated chicken eggs as an alternative system for isolation of equine influenza virus.. Virol J 2017 Jun 21;14(1):120.
    doi: 10.1186/s12985-017-0788-3pmc: PMC5480115pubmed: 28637468google scholar: lookup
  97. Guo Y, Wang M, Kawaoka Y, Gorman O, Ito T, Saito T, Webster RG. Characterization of a new avian-like influenza A virus from horses in China.. Virology 1992 May;188(1):245-55.
    doi: 10.1016/0042-6822(92)90754-Dpubmed: 1314452google scholar: lookup
  98. Gupta AK, Anita A, Vandanajay B. Detection of equine influenza viral genome by RT-PCR and RNA-DNA hybridization. Indian J. Biotech 2, 214–219.
  99. Hale BG, Randall RE, Ortín J, Jackson D. The multifunctional NS1 protein of influenza A viruses.. J Gen Virol 2008 Oct;89(Pt 10):2359-2376.
    doi: 10.1099/vir.0.2008/004606-0pubmed: 18796704google scholar: lookup
  100. Hayward JJ, Dubovi EJ, Scarlett JM, Janeczko S, Holmes EC, Parrish CR. Microevolution of canine influenza virus in shelters and its molecular epidemiology in the United States.. J Virol 2010 Dec;84(24):12636-45.
    doi: 10.1128/JVI.01350-10pmc: PMC3004329pubmed: 20943966google scholar: lookup
  101. Heldens JG, Pouwels HG, Derks CG, Van de Zande SM, Hoeijmakers MJ. The first safe inactivated equine influenza vaccine formulation adjuvanted with ISCOM-Matrix that closes the immunity gap.. Vaccine 2009 Sep 4;27(40):5530-7.
    doi: 10.1016/j.vaccine.2009.06.085pubmed: 19607950google scholar: lookup
  102. Heldens JG, Pouwels HG, van Loon AA. Efficacy and duration of immunity of a combined equine influenza and equine herpesvirus vaccine against challenge with an American-like equine influenza virus (A/equi-2/Kentucky/95).. Vet J 2004 Mar;167(2):150-7.
    doi: 10.1016/S1090-0233(03)00028-5pubmed: 14975389google scholar: lookup
  103. Heldens JG, van Loon AA, van de Zande S. Is there a benefit from an early booster vaccination in the control of equine influenza?. Vet J 2007 Nov;174(3):592-8.
    doi: 10.1016/j.tvjl.2007.03.004pubmed: 17560150google scholar: lookup
  104. Hemann EA, Kang SM, Legge KL. Protective CD8 T cell-mediated immunity against influenza A virus infection following influenza virus-like particle vaccination.. J Immunol 2013 Sep 1;191(5):2486-94.
    doi: 10.4049/jimmunol.1300954pmc: PMC3777857pubmed: 23885108google scholar: lookup
  105. Hinshaw VS, Olsen CW, Dybdahl-Sissoko N, Evans D. Apoptosis: a mechanism of cell killing by influenza A and B viruses.. J Virol 1994 Jun;68(6):3667-73.
    pmc: PMC236871pubmed: 8189504doi: 10.1128/jvi.68.6.3667-3673.1994google scholar: lookup
  106. Holland RE. Equine Influenza. Art. No: 4584. Available online at: www.thehorse.com.
  107. Horspool LJ, King A. Equine influenza vaccines in Europe: a view from the animal health industry.. Equine Vet J 2013 Nov;45(6):774-5.
    doi: 10.1111/evj.12171pubmed: 24117938google scholar: lookup
  108. Hughes J, Allen RC, Baguelin M, Hampson K, Baillie GJ, Elton D, Newton JR, Kellam P, Wood JL, Holmes EC, Murcia PR. Transmission of equine influenza virus during an outbreak is characterized by frequent mixed infections and loose transmission bottlenecks.. PLoS Pathog 2012 Dec;8(12):e1003081.
    doi: 10.1371/journal.ppat.1003081pmc: PMC3534375pubmed: 23308065google scholar: lookup
  109. Ibañez LI, Caldevilla CA, Paredes Rojas Y, Mattion N. Genetic and subunit vaccines based on the stem domain of the equine influenza hemagglutinin provide homosubtypic protection against heterologous strains.. Vaccine 2018 Mar 14;36(12):1592-1598.
    doi: 10.1016/j.vaccine.2018.02.019pubmed: 29454522google scholar: lookup
  110. Ito M, Nagai M, Hayakawa Y, Komae H, Murakami N, Yotsuya S, Asakura S, Sakoda Y, Kida H. Genetic Analyses of an H3N8 Influenza Virus Isolate, Causative Strain of the Outbreak of Equine Influenza at the Kanazawa Racecourse in Japan in 2007.. J Vet Med Sci 2008 Sep;70(9):899-906.
    doi: 10.1292/jvms.70.899pubmed: 18840963google scholar: lookup
  111. Ito T, Kawaoka Y. Host-range barrier of influenza A viruses.. Vet Microbiol 2000 May 22;74(1-2):71-5.
    doi: 10.1016/S0378-1135(00)00167-Xpubmed: 10799779google scholar: lookup
  112. Jagger BW, Wise HM, Kash JC, Walters KA, Wills NM, Xiao YL, Dunfee RL, Schwartzman LM, Ozinsky A, Bell GL, Dalton RM, Lo A, Efstathiou S, Atkins JF, Firth AE, Taubenberger JK, Digard P. An overlapping protein-coding region in influenza A virus segment 3 modulates the host response.. Science 2012 Jul 13;337(6091):199-204.
    doi: 10.1126/science.1222213pmc: PMC3552242pubmed: 22745253google scholar: lookup
  113. Joseph U, Su YC, Vijaykrishna D, Smith GJ. The ecology and adaptive evolution of influenza A interspecies transmission.. Influenza Other Respir Viruses 2017 Jan;11(1):74-84.
    doi: 10.1111/irv.12412pmc: PMC5155642pubmed: 27426214google scholar: lookup
  114. Junquera EC, Mateos-Hernández L, de la Fuente J, de la Lastra JM. Recent advances in the development of anti-infective prophylactic and/or therapeutic agents based on Toll-Like Receptor (TLRs).. Recent Pat Antiinfect Drug Discov 2014;9(1):14-24.
    doi: 10.2174/1574891X09666140616164918pubmed: 25164058google scholar: lookup
  115. Kapoor S, Dhama K. Insight into Influenza Viruses of Animals and Humans. Cham: Springer International Publishing, A. G., 1–222.
  116. Karamendin K, Kydyrmanov A, Kasymbekov Y, Khan E, Daulbayeva K, Asanova S, Zhumatov K, Seidalina A, Sayatov M, Fereidouni SR. Continuing evolution of equine influenza virus in Central Asia, 2007-2012.. Arch Virol 2014 Sep;159(9):2321-7.
    doi: 10.1007/s00705-014-2078-3pubmed: 24748052google scholar: lookup
  117. Kawaoka Y, Bean WJ, Webster RG. Evolution of the hemagglutinin of equine H3 influenza viruses.. Virology 1989 Apr;169(2):283-92.
    doi: 10.1016/0042-6822(89)90153-0pubmed: 2705299google scholar: lookup
  118. Khan A, Mushtaq MH, Ahmad MUD, Nazir J, Farooqi SH, Khan A. Molecular Epidemiology of a novel re-assorted epidemic strain of equine influenza virus in Pakistan in 2015-16.. Virus Res 2017 Aug 15;240:56-63.
    doi: 10.1016/j.virusres.2017.07.022pubmed: 28757141google scholar: lookup
  119. Khurelbaatar N, Krueger WS, Heil GL, Darmaa B, Ulziimaa D, Tserennorov D, Baterdene A, Anderson BD, Gray GC. Sparse evidence for equine or avian influenza virus infections among Mongolian adults with animal exposures.. Influenza Other Respir Viruses 2013 Nov;7(6):1246-50.
    doi: 10.1111/irv.12148pmc: PMC4634246pubmed: 23941547google scholar: lookup
  120. Khurelbaatar N, Krueger WS, Heil GL, Darmaa B, Ulziimaa D, Tserennorov D, Baterdene A, Anderson BD, Gray GC. Little evidence of avian or equine influenza virus infection among a cohort of Mongolian adults with animal exposures, 2010-2011.. PLoS One 2014;9(1):e85616.
    doi: 10.1371/journal.pone.0085616pmc: PMC3897462pubmed: 24465622google scholar: lookup
  121. Kinsley R, Scott SD, Daly JM. Controlling equine influenza: Traditional to next generation serological assays.. Vet Microbiol 2016 May 1;187:15-20.
    doi: 10.1016/j.vetmic.2016.03.006pubmed: 27066704google scholar: lookup
  122. Kirkland PD, Delbridge G. Use of a blocking ELISA for antibodies to equine influenza virus as a test to distinguish between naturally infected and vaccinated horses: proof of concept studies.. Aust Vet J 2011 Jul;89 Suppl 1:45-6.
    doi: 10.1111/j.1751-0813.2011.00743.xpubmed: 21711288google scholar: lookup
  123. Kirkland PD, Finlaison DS, Crispe E, Hurt AC. Influenza virus transmission from horses to dogs, Australia.. Emerg Infect Dis 2010 Apr;16(4):699-702.
    doi: 10.3201/eid1604.091489pmc: PMC3321956pubmed: 20350392google scholar: lookup
  124. Koel BF, Burke DF, Bestebroer TM, van der Vliet S, Zondag GC, Vervaet G, Skepner E, Lewis NS, Spronken MI, Russell CA, Eropkin MY, Hurt AC, Barr IG, de Jong JC, Rimmelzwaan GF, Osterhaus AD, Fouchier RA, Smith DJ. Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution.. Science 2013 Nov 22;342(6161):976-9.
    doi: 10.1126/science.1244730pubmed: 24264991google scholar: lookup
  125. Krumbholz A, Philipps A, Oehring H, Schwarzer K, Eitner A, Wutzler P, Zell R. Current knowledge on PB1-F2 of influenza A viruses.. Med Microbiol Immunol 2011 May;200(2):69-75.
    doi: 10.1007/s00430-010-0176-8pubmed: 20953627google scholar: lookup
  126. Kumar N, Bera BC, Greenbaum BD, Bhatia S, Sood R, Selvaraj P, Anand T, Tripathi BN, Virmani N. Revelation of Influencing Factors in Overall Codon Usage Bias of Equine Influenza Viruses.. PLoS One 2016;11(4):e0154376.
    doi: 10.1371/journal.pone.0154376pmc: PMC4847779pubmed: 27119730google scholar: lookup
  127. Kwasnik M, Gora IM, Rola J, Zmudzinski JF, Rozek W. NS-gene based phylogenetic analysis of equine influenza viruses isolated in Poland.. Vet Microbiol 2016;182:95-101.
    doi: 10.1016/j.vetmic.2015.10.028pubmed: 26711034google scholar: lookup
  128. Laabassi F. Epidemiology of equine influenza viruses. in Epidemiology of Communicable and Non-Communicable Diseases–Attributes of Lifestyle and Nature on Humankind, ed Kasenga F (InTech). Available online at: https://www.intechopen.com/books/epidemiology-of-communicable-and-non-communicable-diseases-attributes-of-lifestyle-and-nature-on-humankind/epidemiology-of-equine-influenza-viruses.
  129. Lai AC, Chambers TM, Holland RE Jr, Morley PS, Haines DM, Townsend HG, Barrandeguy M. Diverged evolution of recent equine-2 influenza (H3N8) viruses in the Western Hemisphere.. Arch Virol 2001;146(6):1063-74.
    doi: 10.1007/s007050170106pubmed: 11504416google scholar: lookup
  130. Lamb RA, Lai CJ. Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus.. Cell 1980 Sep;21(2):475-85.
    doi: 10.1016/0092-8674(80)90484-5pubmed: 7407920google scholar: lookup
  131. Landolt GA. Equine influenza virus.. Vet Clin North Am Equine Pract 2014 Dec;30(3):507-22.
    doi: 10.1016/j.cveq.2014.08.003pubmed: 25282321google scholar: lookup
  132. Landolt GA, Hussey SB, Kreutzer K, Quintana A, Lunn DP. Low-dose DNA vaccination into the submandibular lymph nodes in ponies.. Vet Rec 2010 Aug 21;167(8):302-3.
    doi: 10.1136/vr.c3891pubmed: 20729518google scholar: lookup
  133. Landolt GA, Townsend HGG, Lunn DP. Equine influenza infection. in Equine Infectious Diseases, eds Sellon DC, Long MT (Philadelphia, PA: Saunders; Elsevier Inc.), Chapter 12, 124–134.
  134. Larson KR, Heil GL, Chambers TM, Capuano A, White SK, Gray GC. Serological evidence of equine influenza infections among persons with horse exposure, Iowa.. J Clin Virol 2015 Jun;67:78-83.
    doi: 10.1016/j.jcv.2015.04.009pubmed: 25959164google scholar: lookup
  135. Law J. Influenza in horses. in Report of the Commissioner of Agriculture for the Year 1872, ed Commission of Agriculture (Washington, DC: Government Printing Office; ), 203–248.
  136. Lee E, Kim EJ, Shin YK, Song JY. Design and testing of multiplex RT-PCR primers for the rapid detection of influenza A virus genomic segments: Application to equine influenza virus.. J Virol Methods 2016 Feb;228:114-22.
    doi: 10.1016/j.jviromet.2015.11.012pubmed: 26655588google scholar: lookup
  137. Lee J, Park JH, Min JY. A naturally truncated NS1 protein of influenza A virus impairs its interferon-antagonizing activity and thereby confers attenuation in vitro.. Arch Virol 2017 Jan;162(1):13-21.
    doi: 10.1007/s00705-016-2966-9pubmed: 27400993google scholar: lookup
  138. Legrand LJ, Pitel PH, Cullinane AA, Fortier GD, Pronost SL. Genetic evolution of equine influenza strains isolated in France from 2005 to 2010.. Equine Vet J 2015 Mar;47(2):207-11.
    doi: 10.1111/evj.12244pubmed: 25763436google scholar: lookup
  139. Lewis NS, Anderson TK, Kitikoon P, Skepner E, Burke DF, Vincent AL. Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine.. J Virol 2014 May;88(9):4752-63.
    doi: 10.1128/JVI.03805-13pmc: PMC3993788pubmed: 24522915google scholar: lookup
  140. Lewis NS, Daly JM, Russell CA, Horton DL, Skepner E, Bryant NA, Burke DF, Rash AS, Wood JL, Chambers TM, Fouchier RA, Mumford JA, Elton DM, Smith DJ. Antigenic and genetic evolution of equine influenza A (H3N8) virus from 1968 to 2007.. J Virol 2011 Dec;85(23):12742-9.
    doi: 10.1128/JVI.05319-11pmc: PMC3209411pubmed: 21937642google scholar: lookup
  141. Lin C, Holland RE Jr, Donofrio JC, McCoy MH, Tudor LR, Chambers TM. Caspase activation in equine influenza virus induced apoptotic cell death.. Vet Microbiol 2002 Feb 4;84(4):357-65.
    doi: 10.1016/S0378-1135(01)00468-0pubmed: 11750143google scholar: lookup
  142. Livesay GJ, O'Neill T, Hannant D, Yadav MP, Mumford JA. The outbreak of equine influenza (H3N8) in the United Kingdom in 1989: diagnostic use of an antigen capture ELISA.. Vet Rec 1993 Nov 20;133(21):515-9.
    pubmed: 8310627doi: 10.1136/vr.133.21.515google scholar: lookup
  143. Lu Z, Chambers TM, Boliar S, Branscum AJ, Sturgill TL, Timoney PJ, Reedy SE, Tudor LR, Dubovi EJ, Vickers ML, Sells S, Balasuriya UB. Development and evaluation of one-step TaqMan real-time reverse transcription-PCR assays targeting nucleoprotein, matrix, and hemagglutinin genes of equine influenza virus.. J Clin Microbiol 2009 Dec;47(12):3907-13.
    doi: 10.1128/JCM.00598-09pmc: PMC2786649pubmed: 19846644google scholar: lookup
  144. Lunn DP, Soboll G, Schram BR, Quass J, McGregor MW, Drape RJ, Macklin MD, McCabe DE, Swain WF, Olsen CW. Antibody responses to DNA vaccination of horses using the influenza virus hemagglutinin gene.. Vaccine 1999 May 4;17(18):2245-58.
    doi: 10.1016/S0264-410X(98)00496-4pubmed: 10403592google scholar: lookup
  145. Major DA. Hygiene practices to prevent the spread of equine influenza by humans.. Aust Vet J 2011 Jul;89 Suppl 1:124-5.
    doi: 10.1111/j.1751-0813.2011.00765.xpubmed: 21711309google scholar: lookup
  146. Malik YS, Sharma K, Jeena LM, Kumar N, Sircar S, Rajak KK. Toll-like receptors: the innate immune receptors with ingenious anti-viral paradigm. South Asian J. Exp. Biol 3, 207–213.
  147. MANJREKAR SL, GORHE DS, PARANJAPE VL. OBSERVATIONS ON THE COUGHING OUTBREAK "NEWMARKET COUGH" IN THE RACE HORSES IN BOMBAY.. Indian Vet J 1965 Jul;42:461-4.
    pubmed: 14338093
  148. Mathew T, Dhama K, Pawaiya RVS, Mahendran M. Equine influenza. in Advances in Medical and Veterinary Virology, Immunology, and Epidemiology–Vol. 7: Tropical Viral Diseases of Large Domestic Animals–Part 1, ed Mathew T (West Orange, NJ; United Kingdom: Thajema Publishers; Xlibris Corporation; ), Chapter 133–151.
  149. Mathew T, Mahendran M, Dhama K. Equine influenza (Chapter VII). in Advances in Medical & Veterinary Virology, Immunology and Epidemiology, Vol. 6: Influenza and it's Public Health Significance, eds: Mathew TM, Mathew T (West Orange, NJ: Thajema Publishers; ), 112–129.
  150. McAuley JL, Kedzierska K, Brown LE, Shanks GD. Host Immunological Factors Enhancing Mortality of Young Adults during the 1918 Influenza Pandemic.. Front Immunol 2015;6:419.
    doi: 10.3389/fimmu.2015.00419pmc: PMC4541073pubmed: 26347742google scholar: lookup
  151. McKinstry KK, Dutton RW, Swain SL, Strutt TM. Memory CD4 T cell-mediated immunity against influenza A virus: more than a little helpful.. Arch Immunol Ther Exp (Warsz) 2013 Oct;61(5):341-53.
    doi: 10.1007/s00005-013-0236-zpmc: PMC3874125pubmed: 23708562google scholar: lookup
  152. Meeusen EN, Walker J, Peters A, Pastoret PP, Jungersen G. Current status of veterinary vaccines.. Clin Microbiol Rev 2007 Jul;20(3):489-510, table of contents.
    doi: 10.1128/CMR.00005-07pmc: PMC1932753pubmed: 17630337google scholar: lookup
  153. Meseko CA, Ehizibolo DO, Nwokike EC, Wungak YS. Serological evidence of equine influenza virus in horse stables in Kaduna, Nigeria.. J Equine Sci 2016;27(3):99-105.
    doi: 10.1294/jes.27.99pmc: PMC5048356pubmed: 27703404google scholar: lookup
  154. Minke JM, Audonnet JC, Fischer L. Equine viral vaccines: the past, present and future.. Vet Res 2004 Jul-Aug;35(4):425-43.
    doi: 10.1051/vetres:2004019pubmed: 15236675google scholar: lookup
  155. Minke JM, Toulemonde CE, Coupier H, Guigal PM, Dinic S, Sindle T, Jessett D, Black L, Bublot M, Pardo MC, Audonnet JC. Efficacy of a canarypox-vectored recombinant vaccine expressing the hemagglutinin gene of equine influenza H3N8 virus in the protection of ponies from viral challenge.. Am J Vet Res 2007 Feb;68(2):213-9.
    doi: 10.2460/ajvr.68.2.213pubmed: 17269889google scholar: lookup
  156. Moattari A, Ashrafi H, Kadivar MR, Kheiri MT, Shahidi M, Arabpour M, Ghanbari A. Antigenic variations of human influenza virus in Shiraz, Iran.. Indian J Med Microbiol 2010 Apr-Jun;28(2):114-9.
    doi: 10.4103/0255-0857.62486pubmed: 20404455google scholar: lookup
  157. Morens DM, Taubenberger JK. Historical thoughts on influenza viral ecosystems, or behold a pale horse, dead dogs, failing fowl, and sick swine.. Influenza Other Respir Viruses 2010 Nov;4(6):327-37.
    doi: 10.1111/j.1750-2659.2010.00148.xpmc: PMC3180823pubmed: 20958926google scholar: lookup
  158. Morley PS, Townsend HG, Bogdan JR, Haines DM. Descriptive epidemiologic study of disease associated with influenza virus infections during three epidemics in horses.. J Am Vet Med Assoc 2000 Feb 15;216(4):535-44.
    doi: 10.2460/javma.2000.216.535pubmed: 10687009google scholar: lookup
  159. Mumford JA. The diagnosis and control of equine influenza. Proc. Am. Assoc. Equine Pract 36:377.
  160. Mumford J, Wood J. WHO/OIE meeting: consultation on newly emerging strains of equine influenza. 18-19 May 1992, Animal Health Trust, Newmarket, Suffolk, UK.. Vaccine 1993;11(11):1172-5.
    doi: 10.1016/0264-410X(93)90092-Cpubmed: 8249440google scholar: lookup
  161. Murcia PR, Baillie GJ, Daly J, Elton D, Jervis C, Mumford JA, Newton R, Parrish CR, Hoelzer K, Dougan G, Parkhill J, Lennard N, Ormond D, Moule S, Whitwham A, McCauley JW, McKinley TJ, Holmes EC, Grenfell BT, Wood JL. Intra- and interhost evolutionary dynamics of equine influenza virus.. J Virol 2010 Jul;84(14):6943-54.
    doi: 10.1128/JVI.00112-10pmc: PMC2898244pubmed: 20444896google scholar: lookup
  162. Murcia PR, Baillie GJ, Stack JC, Jervis C, Elton D, Mumford JA, Daly J, Kellam P, Grenfell BT, Holmes EC, Wood JL. Evolution of equine influenza virus in vaccinated horses.. J Virol 2013 Apr;87(8):4768-71.
    doi: 10.1128/JVI.03379-12pmc: PMC3624384pubmed: 23388708google scholar: lookup
  163. Na W, Kang B, Kim HI, Hong M, Park SJ, Jeoung HY, An DJ, Moon H, Kim JK, Song D. Isolation and genetic characterization of naturally NS-truncated H3N8 equine influenza virus in South Korea.. Epidemiol Infect 2014 Apr;142(4):759-66.
    doi: 10.1017/S095026881300143Xpubmed: 23800580google scholar: lookup
  164. Na W, Yeom M, Yuk H, Moon H, Kang B, Song D. Influenza virus vaccine for neglected hosts: horses and dogs.. Clin Exp Vaccine Res 2016 Jul;5(2):117-24.
    doi: 10.7774/cevr.2016.5.2.117pmc: PMC4969275pubmed: 27489801google scholar: lookup
  165. Nedland H, Wollman J, Sreenivasan C, Quast M, Singrey A, Fawcett L, Christopher-Hennings J, Nelson E, Kaushik RS, Wang D, Li F. Serological evidence for the co-circulation of two lineages of influenza D viruses in equine populations of the Midwest United States.. Zoonoses Public Health 2018 Feb;65(1):e148-e154.
    doi: 10.1111/zph.12423pmc: PMC5766371pubmed: 29139222google scholar: lookup
  166. Nelson KM, Schram BR, McGregor MW, Sheoran AS, Olsen CW, Lunn DP. Local and systemic isotype-specific antibody responses to equine influenza virus infection versus conventional vaccination.. Vaccine 1998 Aug;16(13):1306-13.
    doi: 10.1016/S0264-410X(98)00009-7pubmed: 9682395google scholar: lookup
  167. Nemoto M, Yamanaka T, Bannai H, Tsujimura K, Kokado H. Complete Genomic Sequences of H3N8 Equine Influenza Virus Strains Used as Vaccine Strains in Japan.. Genome Announc 2018 Mar 22;6(12).
    doi: 10.1128/genomeA.00172-18pmc: PMC5864938pubmed: 29567739google scholar: lookup
  168. Nemoto M, Yamanaka T, Bannai H, Tsujimura K, Kondo T, Matsumura T. Development and evaluation of a reverse transcription loop-mediated isothermal amplification assay for H3N8 equine influenza virus.. J Virol Methods 2011 Dec;178(1-2):239-42.
    doi: 10.1016/j.jviromet.2011.07.015pubmed: 21907240google scholar: lookup
  169. Nemoto M, Yamanaka T, Bannai H, Tsujimura K, Kondo T, Matsumura T. Development of a reverse transcription loop-mediated isothermal amplification assay for H7N7 equine influenza virus.. J Vet Med Sci 2012 Jul;74(7):929-31.
    doi: 10.1292/jvms.11-0541pubmed: 22362254google scholar: lookup
  170. Newton JR, Mumford JA. Equine influenza. in Infectious Diseases of Livestock, Vol. 1, ed Coetzer JAW, Tustin RC (Oxford: Oxford University Press; ), 766–774.
  171. Newton R, Cooke A, Elton D, Bryant N, Rash A, Bowman S, Blunden T, Miller J, Hammond TA, Camm I, Day M. Canine influenza virus: cross-species transmission from horses.. Vet Rec 2007 Jul 28;161(4):142-3.
    doi: 10.1136/vr.161.4.142-apubmed: 17660470google scholar: lookup
  172. Nogales A, Martínez-Sobrido L. Reverse Genetics Approaches for the Development of Influenza Vaccines.. Int J Mol Sci 2016 Dec 22;18(1).
    doi: 10.3390/ijms18010020pmc: PMC5297655pubmed: 28025504google scholar: lookup
  173. . National Research Central on Equines, Annual Report 2009–2010. NRCE Annual Report (2010). 21 pp. Available online at: http://nrce.gov.in/downloads/NRCE%20Annual%20Report%202009-10.pdf.
  174. OIE. Equine Influenza. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals Chapter 2.5.7 (Paris: Office International Des Epizooties; ), 871–883.
  175. Oishi K, Yamayoshi S, Kawaoka Y. Identification of novel amino acid residues of influenza virus PA-X that are important for PA-X shutoff activity by using yeast.. Virology 2018 Mar;516:71-75.
    doi: 10.1016/j.virol.2018.01.004pmc: PMC6296753pubmed: 29331676google scholar: lookup
  176. Olsen CW. DNA vaccination against influenza viruses: a review with emphasis on equine and swine influenza.. Vet Microbiol 2000 May 22;74(1-2):149-64.
    doi: 10.1016/S0378-1135(00)00175-9pubmed: 10799787google scholar: lookup
  177. Oxburgh L, Hagström A. A PCR based method for the identification of equine influenza virus from clinical samples.. Vet Microbiol 1999 Jun 30;67(3):161-74.
    doi: 10.1016/S0378-1135(99)00041-3pubmed: 10418871google scholar: lookup
  178. Oxburgh L, Klingeborn B. Cocirculation of two distinct lineages of equine influenza virus subtype H3N8.. J Clin Microbiol 1999 Sep;37(9):3005-9.
    pmc: PMC85435pubmed: 10449491doi: 10.1128/jcm.37.9.3005-3009.1999google scholar: lookup
  179. Ozaki H, Sugita S, Kida H. A rapid and highly sensitive method for diagnosis of equine influenza by antigen detection using immuno-PCR.. Jpn J Vet Res 2001 Feb;48(4):187-95.
    pubmed: 11276583
  180. Paillot R. A Systematic Review of Recent Advances in Equine Influenza Vaccination.. Vaccines (Basel) 2014 Nov 14;2(4):797-831.
    doi: 10.3390/vaccines2040797pmc: PMC4494246pubmed: 26344892google scholar: lookup
  181. Paillot R, El-Hage CM. The Use of a Recombinant Canarypox-Based Equine Influenza Vaccine during the 2007 Australian Outbreak: A Systematic Review and Summary.. Pathogens 2016 Jun 10;5(2).
    doi: 10.3390/pathogens5020042pmc: PMC4931393pubmed: 27294963google scholar: lookup
  182. Paillot R, Grimmett H, Elton D, Daly JM. Protection, systemic IFNgamma, and antibody responses induced by an ISCOM-based vaccine against a recent equine influenza virus in its natural host.. Vet Res 2008 May-Jun;39(3):21.
    doi: 10.1051/vetres:2007062pubmed: 18252187google scholar: lookup
  183. Paillot R, Hannant D, Kydd JH, Daly JM. Vaccination against equine influenza: quid novi?. Vaccine 2006 May 8;24(19):4047-61.
    doi: 10.1016/j.vaccine.2006.02.030pubmed: 16545507google scholar: lookup
  184. Paillot R, Kydd JH, Sindle T, Hannant D, Edlund Toulemonde C, Audonnet JC, Minke JM, Daly JM. Antibody and IFN-gamma responses induced by a recombinant canarypox vaccine and challenge infection with equine influenza virus.. Vet Immunol Immunopathol 2006 Aug 15;112(3-4):225-33.
    doi: 10.1016/j.vetimm.2006.02.007pubmed: 16621023google scholar: lookup
  185. Paillot R, Rash NL, Garrett D, Prowse-Davis L, Montesso F, Cullinane A, Lemaitre L, Thibault JC, Wittreck S, Dancer A. How to Meet the Last OIE Expert Surveillance Panel Recommendations on Equine Influenza (EI) Vaccine Composition: A Review of the Process Required for the Recombinant Canarypox-Based EI Vaccine.. Pathogens 2016 Nov 25;5(4).
    doi: 10.1111/evj.12323_29pmc: PMC5198164pubmed: 27897990google scholar: lookup
  186. Paillot R, Marcillaud Pitel C, D'Ablon X, Pronost S. Equine Vaccines: How, When and Why? Report of the Vaccinology Session, French Equine Veterinarians Association, 2016, Reims.. Vaccines (Basel) 2017 Dec 4;5(4).
    doi: 10.3390/vaccines5040046pmc: PMC5748612pubmed: 29207516google scholar: lookup
  187. Paillot R, Prowse L. ISCOM-matrix-based equine influenza (EIV) vaccine stimulates cell-mediated immunity in the horse.. Vet Immunol Immunopathol 2012 Jan 15;145(1-2):516-21.
    doi: 10.1016/j.vetimm.2011.11.019pubmed: 22178272google scholar: lookup
  188. Paillot R, Prowse L, Donald C, Medcalf E, Montesso F, Bryant N, Watson J, Jeggo M, Elton D, Newton R, Trail P, Barnes H. Efficacy of a whole inactivated EI vaccine against a recent EIV outbreak isolate and comparative detection of virus shedding.. Vet Immunol Immunopathol 2010 Aug 15;136(3-4):272-83.
    doi: 10.1016/j.vetimm.2010.03.019pubmed: 20400185google scholar: lookup
  189. Paillot R, Prowse L, Montesso F, Huang CM, Barnes H, Escala J. Whole inactivated equine influenza vaccine: Efficacy against a representative clade 2 equine influenza virus, IFNgamma synthesis and duration of humoral immunity.. Vet Microbiol 2013 Mar 23;162(2-4):396-407.
    doi: 10.1016/j.vetmic.2012.10.019pubmed: 23146168google scholar: lookup
  190. Paillot R, Prowse L, Montesso F, Stewart B, Jordon L, Newton JR, Gilkerson JR. Duration of equine influenza virus shedding and infectivity in immunised horses after experimental infection with EIV A/eq2/Richmond/1/07.. Vet Microbiol 2013 Sep 27;166(1-2):22-34.
    doi: 10.1016/j.vetmic.2013.04.027pubmed: 23769636google scholar: lookup
  191. Park AW, Daly JM, Lewis NS, Smith DJ, Wood JL, Grenfell BT. Quantifying the impact of immune escape on transmission dynamics of influenza.. Science 2009 Oct 30;326(5953):726-8.
    doi: 10.1126/science.1175980pmc: PMC3800096pubmed: 19900931google scholar: lookup
  192. Park AW, Wood JL, Newton JR, Daly J, Mumford JA, Grenfell BT. Optimising vaccination strategies in equine influenza.. Vaccine 2003 Jun 20;21(21-22):2862-70.
    doi: 10.1016/S0264-410X(03)00156-7pubmed: 12798628google scholar: lookup
  193. Parrish CR, Murcia PR, Holmes EC. Influenza virus reservoirs and intermediate hosts: dogs, horses, and new possibilities for influenza virus exposure of humans.. J Virol 2015 Mar;89(6):2990-4.
    doi: 10.1128/JVI.03146-14pmc: PMC4337525pubmed: 25540375google scholar: lookup
  194. Paterson D, Fodor E. Emerging roles for the influenza A virus nuclear export protein (NEP).. PLoS Pathog 2012;8(12):e1003019.
    doi: 10.1371/journal.ppat.1003019pmc: PMC3516560pubmed: 23236273google scholar: lookup
  195. Patterson-Kane JC, Carrick JB, Axon JE, Wilkie I, Begg AP. The pathology of bronchointerstitial pneumonia in young foals associated with the first outbreak of equine influenza in Australia.. Equine Vet J 2008 May;40(3):199-203.
    doi: 10.2746/042516408X292214pubmed: 18321807google scholar: lookup
  196. Pavulraj S, Bera BC, Joshi A, Anand T, Virmani M, Vaid RK, Shanmugasundaram K, Gulati BR, Rajukumar K, Singh R, Misri J, Singh RK, Tripathi BN, Virmani N. Pathology of Equine Influenza virus (H3N8) in Murine Model.. PLoS One 2015;10(11):e0143094.
    doi: 10.1371/journal.pone.0143094pmc: PMC4654517pubmed: 26587990google scholar: lookup
  197. Pavulraj S, Virmani N, Bera BC, Joshi A, Anand T, Virmani M, Singh R, Singh RK, Tripathi BN. Immunogenicity and protective efficacy of inactivated equine influenza (H3N8) virus vaccine in murine model.. Vet Microbiol 2017 Oct;210:188-196.
    doi: 10.1016/j.vetmic.2017.08.013pubmed: 29103691google scholar: lookup
  198. Pecoraro HL, Bennett S, Garretson K, Quintana AM, Lunn KF, Landolt GA. Comparison of the Infectivity and Transmission of Contemporary Canine and Equine H3N8 Influenza Viruses in Dogs.. Vet Med Int 2013;2013:874521.
    doi: 10.1155/2013/874521pmc: PMC3808106pubmed: 24198997google scholar: lookup
  199. Olguin Perglione C, Golemba MD, Torres C, Barrandeguy M. Molecular Epidemiology and Spatio-Temporal Dynamics of the H3N8 Equine Influenza Virus in South America.. Pathogens 2016 Oct 16;5(4).
    doi: 10.3390/pathogens5040061pmc: PMC5198161pubmed: 27754468google scholar: lookup
  200. Perkins NR, Webster WR, Wright T, Denney I, Links I. Vaccination program in the response to the 2007 equine influenza outbreak in Australia.. Aust Vet J 2011 Jul;89 Suppl 1:126-34.
    doi: 10.1111/j.1751-0813.2011.00766.xpubmed: 21711310google scholar: lookup
  201. Prasad M, Lambe UP, Brar B, Shah I, J M, Ranjan K, Rao R, Kumar S, Mahant S, Khurana SK, Iqbal HMN, Dhama K, Misri J, Prasad G. Nanotherapeutics: An insight into healthcare and multi-dimensional applications in medical sector of the modern world.. Biomed Pharmacother 2018 Jan;97:1521-1537.
    doi: 10.1016/j.biopha.2017.11.026pubmed: 29793315google scholar: lookup
  202. Purzycka M, Rozek W, Zmudzinski JF. Global distribution of equine influenza. Med. Weter 60, 675–679.
  203. Qi T, Guo W, Huang WQ, Li HM, Zhao LP, Dai LL, He N, Hao XF, Xiang WH. Genetic evolution of equine influenza viruses isolated in China.. Arch Virol 2010 Sep;155(9):1425-32.
    doi: 10.1007/s00705-010-0724-ypubmed: 20559670google scholar: lookup
  204. Quinlivan M, Zamarin D, García-Sastre A, Cullinane A, Chambers T, Palese P. Attenuation of equine influenza viruses through truncations of the NS1 protein.. J Virol 2005 Jul;79(13):8431-9.
    doi: 10.1128/JVI.79.13.8431-8439.2005pmc: PMC1143746pubmed: 15956587google scholar: lookup
  205. Radostits OM, Gay CC, Blood DC, Hinchcliff KW. Equine influenza. in Veterinary Medicine, A Text Book of Diseases of Cattle, Sheep, Pigs, Goats and Horses, 9th Edn (New York, NY: Elsevier Saunders; ), 1144–1147.
  206. Rash A, Morton R, Woodward A, Maes O, McCauley J, Bryant N, Elton D. Evolution and Divergence of H3N8 Equine Influenza Viruses Circulating in the United Kingdom from 2013 to 2015.. Pathogens 2017 Feb 8;6(1).
    doi: 10.3390/pathogens6010006pmc: PMC5371894pubmed: 28208721google scholar: lookup
  207. Read AJ, Arzey KE, Finlaison DS, Gu X, Davis RJ, Ritchie L, Kirkland PD. A prospective longitudinal study of naturally infected horses to evaluate the performance characteristics of rapid diagnostic tests for equine influenza virus.. Vet Microbiol 2012 May 4;156(3-4):246-55.
    doi: 10.1016/j.vetmic.2011.10.031pubmed: 22115969google scholar: lookup
  208. Rivailler P, Perry IA, Jang Y, Davis CT, Chen LM, Dubovi EJ, Donis RO. Evolution of canine and equine influenza (H3N8) viruses co-circulating between 2005 and 2008.. Virology 2010 Dec 5;408(1):71-9.
    doi: 10.1016/j.virol.2010.08.022pubmed: 20880564google scholar: lookup
  209. Rodriguez L, Reedy S, Nogales A, Murcia PR, Chambers TM, Martinez-Sobrido L. Development of a novel equine influenza virus live-attenuated vaccine.. Virology 2018 Mar;516:76-85.
    doi: 10.1016/j.virol.2018.01.005pmc: PMC5840510pubmed: 29331866google scholar: lookup
  210. Rosanowski SM, Cogger N, Rogers CW, Stevenson MA. Evaluating the Effectiveness of Strategies for the Control of Equine Influenza Virus in the New Zealand Equine Population.. Transbound Emerg Dis 2016 Jun;63(3):321-32.
    doi: 10.1111/tbed.12277pubmed: 25287746google scholar: lookup
  211. Rozek W, Kwasnik M, Zmudzinski JF. Detection of antibodies against equine influenza virus by cell based enzyme-linked immunosorbent assay. Bull. Vet. Inst. Pulawy 55, 569–574.
  212. Sack A, Daramragchaa U, Chuluunbaatar M, Gonchigoo B, Bazartseren B, Tsogbadrakh N, Gray GC. Low Prevalence of Enzootic Equine Influenza Virus among Horses in Mongolia.. Pathogens 2017 Nov 30;6(4).
    doi: 10.3390/pathogens6040061pmc: PMC5750585pubmed: 29189713google scholar: lookup
  213. Sajid M, Ahmad MU, Khan MA, Anjum MA, Mushtaq MH. Investigation of equine influenza virus in two geographical regions of Pakistan.. Trop Anim Health Prod 2013 Feb;45(2):693-4.
    doi: 10.1007/s11250-012-0247-5pubmed: 22923059google scholar: lookup
  214. Schemann K, Firestone SM, Taylor MR, Toribio JA, Ward MP, Dhand NK. Horse owners'/managers' perceptions about effectiveness of biosecurity measures based on their experiences during the 2007 equine influenza outbreak in Australia.. Prev Vet Med 2012 Sep 15;106(2):97-107.
    doi: 10.1016/j.prevetmed.2012.01.013pubmed: 22326045google scholar: lookup
  215. Scocco P, Pedini V. Localization of influenza virus sialoreceptors in equine respiratory tract.. Histol Histopathol 2008 Aug;23(8):973-8.
    doi: 10.14670/HH-23.973pubmed: 18498072google scholar: lookup
  216. Shi W, Lei F, Zhu C, Sievers F, Higgins DG. A complete analysis of HA and NA genes of influenza A viruses.. PLoS One 2010 Dec 29;5(12):e14454.
    doi: 10.1371/journal.pone.0014454pmc: PMC3012125pubmed: 21209922google scholar: lookup
  217. Short KR, Richard M, Verhagen JH, van Riel D, Schrauwen EJ, van den Brand JM, Mänz B, Bodewes R, Herfst S. One health, multiple challenges: The inter-species transmission of influenza A virus.. One Health 2015 Dec 1;1:1-13.
    doi: 10.1016/j.onehlt.2015.03.001pmc: PMC4542011pubmed: 26309905google scholar: lookup
  218. Slater J, Hannant D. Equine immunity to viruses.. Vet Clin North Am Equine Pract 2000 Apr;16(1):49-68.
    doi: 10.1016/S0749-0739(17)30118-9pubmed: 10752138google scholar: lookup
  219. Smyth B. Equine influenza: an update.. Aust Vet J 2007 Dec;85(12):N14, N16.
    pubmed: 18042164doi: 10.1111/j.1751-0813.2007.00225.xgoogle scholar: lookup
  220. Soboll G, Horohov DW, Aldridge BM, Olsen CW, McGregor MW, Drape RJ, Macklin MD, Swain WF, Lunn DP. Regional antibody and cellular immune responses to equine influenza virus infection, and particle mediated DNA vaccination.. Vet Immunol Immunopathol 2003 Jul 15;94(1-2):47-62.
    doi: 10.1016/S0165-2427(03)00060-6pubmed: 12842611google scholar: lookup
  221. Soboll G, Hussey SB, Minke JM, Landolt GA, Hunter JS, Jagannatha S, Lunn DP. Onset and duration of immunity to equine influenza virus resulting from canarypox-vectored (ALVAC) vaccination.. Vet Immunol Immunopathol 2010 May 15;135(1-2):100-107.
    doi: 10.1016/j.vetimm.2009.11.007pubmed: 20018384google scholar: lookup
  222. Solórzano A, Foni E, Córdoba L, Baratelli M, Razzuoli E, Bilato D, Martín del Burgo MÁ, Perlin DS, Martínez J, Martínez-Orellana P, Fraile L, Chiapponi C, Amadori M, del Real G, Montoya M. Cross-Species Infectivity of H3N8 Influenza Virus in an Experimental Infection in Swine.. J Virol 2015 Nov;89(22):11190-202.
    doi: 10.1128/JVI.01509-15pmc: PMC4645675pubmed: 26311894google scholar: lookup
  223. SOVINOVA O, TUMOVA B, POUSKA F, NEMEC J. Isolation of a virus causing respiratory disease in horses.. Acta Virol 1958 Jan-Mar;2(1):52-61.
    pubmed: 13533033
  224. Sreenivasan CC, Jandhyala SS, Luo S, Hause BM, Thomas M, Knudsen DEB, Leslie-Steen P, Clement T, Reedy SE, Chambers TM, Christopher-Hennings J, Nelson E, Wang D, Kaushik RS, Li F. Phylogenetic Analysis and Characterization of a Sporadic Isolate of Equine Influenza A H3N8 from an Unvaccinated Horse in 2015.. Viruses 2018 Jan 11;10(1).
    doi: 10.3390/v10010031pmc: PMC5795444pubmed: 29324680google scholar: lookup
  225. Stack JC, Murcia PR, Grenfell BT, Wood JL, Holmes EC. Inferring the inter-host transmission of influenza A virus using patterns of intra-host genetic variation.. Proc Biol Sci 2013 Jan 7;280(1750):20122173.
    doi: 10.1098/rspb.2012.2173pmc: PMC3574438pubmed: 23135678google scholar: lookup
  226. Su S, Wang L, Fu X, He S, Hong M, Zhou P, Lai A, Gray G, Li S. Equine influenza A(H3N8) virus infection in cats.. Emerg Infect Dis 2014 Dec;20(12):2096-9.
    doi: 10.3201/eid2012.140867pmc: PMC4257791pubmed: 25417790google scholar: lookup
  227. Suzuki Y. [Receptor sialylsugar chains as determinants of host range of influenza viruses].. Nihon Rinsho 2000 Nov;58(11):2206-10.
    pubmed: 11225305
  228. Sylte MJ, Suarez DL. Influenza neuraminidase as a vaccine antigen. in Vaccines for Pandemic Influenza. Current Topics in Microbiology and Immunology, Vol. 333, ed Compans R., Orenstein W. (Berlin; Heidelberg: Springer; ).
  229. Tabynov K, Kydyrbayev Z, Ryskeldinova S, Assanzhanova N, Kozhamkulov Y, Inkarbekov D, Sansyzbay A. Safety and immunogenicity of a novel cold-adapted modified-live equine influenza virus vaccine.. Aust Vet J 2014 Nov;92(11):450-7.
    doi: 10.1111/avj.12248pubmed: 25348146google scholar: lookup
  230. Takahashi T, Unuma S, Kawagishi S, Kurebayashi Y, Takano M, Yoshino H, Minami A, Yamanaka T, Otsubo T, Ikeda K, Suzuki T. Substrate Specificity of Equine and Human Influenza A Virus Sialidase to Molecular Species of Sialic Acid.. Biol Pharm Bull 2016;39(10):1728-1733.
    doi: 10.1248/bpb.b16-00345pubmed: 27725453google scholar: lookup
  231. Timoney PJ. Equine influenza.. Comp Immunol Microbiol Infect Dis 1996 Jun;19(3):205-11.
    doi: 10.1016/0147-9571(96)00006-9pubmed: 8800546google scholar: lookup
  232. Townsend HG, Penner SJ, Watts TC, Cook A, Bogdan J, Haines DM, Griffin S, Chambers T, Holland RE, Whitaker-Dowling P, Youngner JS, Sebring RW. Efficacy of a cold-adapted, intranasal, equine influenza vaccine: challenge trials.. Equine Vet J 2001 Nov;33(7):637-43.
    doi: 10.2746/042516401776249354pubmed: 11770983google scholar: lookup
  233. Townsend HGG, Cook A, Watts TC. Efficacy of a cold-adapted, modified-live virus influenza vaccine: a double-blind challenge trial. Proc. Am. Assoc. Equine Pract 45, 41–42.
  234. Tu J, Zhou H, Jiang T, Li C, Zhang A, Guo X, Zou W, Chen H, Jin M. Isolation and molecular characterization of equine H3N8 influenza viruses from pigs in China.. Arch Virol 2009;154(5):887-90.
    doi: 10.1007/s00705-009-0381-1pubmed: 19396578google scholar: lookup
  235. Uppal PK, Yadav MP. Outbreak of equine influenza in India.. Vet Rec 1987 Dec 12;121(24):569-70.
    pubmed: 2829407
  236. Uppal PK, Yadav MP, Oberoi MS. Isolation of A/Equi-2 virus during 1987 equine influenza epidemic in India.. Equine Vet J 1989 Sep;21(5):364-6.
    doi: 10.1111/j.2042-3306.1989.tb02690.xpubmed: 2550218google scholar: lookup
  237. Uppal PK, Yadav MP, Sharma SN. Occurrence of equine influenza outbreaks in India. Indian J. Comp. Microbiol. Immunol. Infect. Dis 8, 91–94.
  238. Van de Walle GR, May MA, Peters ST, Metzger SM, Rosas CT, Osterrieder N. A vectored equine herpesvirus type 1 (EHV-1) vaccine elicits protective immune responses against EHV-1 and H3N8 equine influenza virus.. Vaccine 2010 Jan 22;28(4):1048-55.
    doi: 10.1016/j.vaccine.2009.10.123pubmed: 19897066google scholar: lookup
  239. van Maanen C, Cullinane A. Equine influenza virus infections: an update.. Vet Q 2002 Jun;24(2):79-94.
    doi: 10.1080/01652176.2002.9695127pubmed: 12095083google scholar: lookup
  240. Virmani N, Bera BC, Gulati BR, Karuppusamy S, Singh BK, Kumar Vaid R, Kumar S, Kumar R, Malik P, Khurana SK, Singh J, Manuja A, Dedar R, Gupta AK, Yadav SC, Chugh PK, Narwal PS, Thankur VL, Kaul R, Kanani A, Rautmare SS, Singh RK. Descriptive epidemiology of equine influenza in India (2008-2009): temporal and spatial trends.. Vet Ital 2010 Oct-Dec;46(4):449-58.
    pubmed: 21120800
  241. Virmani N, Bera BC, Shanumugasundaram K, Singh BK, Gulati BR, Singh RK, Vaid RK. Genetic analysis of the matrix and non-structural genes of equine influenza virus (H3N8) from epizootic of 2008-2009 in India.. Vet Microbiol 2011 Aug 26;152(1-2):169-75.
    doi: 10.1016/j.vetmic.2011.04.011pubmed: 21620592google scholar: lookup
  242. Virmani N, Bera BC, Singh BK, Shanmugasundaram K, Gulati BR, Barua S, Vaid RK, Gupta AK, Singh RK. Equine influenza outbreak in India (2008-09): virus isolation, sero-epidemiology and phylogenetic analysis of HA gene.. Vet Microbiol 2010 Jul 14;143(2-4):224-37.
    doi: 10.1016/j.vetmic.2009.12.007pubmed: 20053509google scholar: lookup
  243. Virmani N, Singh BK, Gulati BR, Kumar S. Equine influenza outbreak in India.. Vet Rec 2008 Nov 15;163(20):607-8.
    doi: 10.1136/vr.163.20.607-apubmed: 19011253google scholar: lookup
  244. WADDELL GH, TEIGLAND MB, SIGEL MM. A NEW INFLUENZA VIRUS ASSOCIATED WITH EQUINE RESPIRATORY DISEASE.. J Am Vet Med Assoc 1963 Sep 15;143:587-90.
    pubmed: 14077956
  245. Wang C, Wang Q, Hu J, Sun H, Pu J, Liu J, Sun Y. A Multiplex RT-PCR Assay for Detection and Differentiation of Avian-Origin Canine H3N2, Equine-Origin H3N8, Human-Origin H3N2, and H1N1/2009 Canine Influenza Viruses.. PLoS One 2017;12(1):e0170374.
    doi: 10.1371/journal.pone.0170374pmc: PMC5249048pubmed: 28107507google scholar: lookup
  246. Watson J, Daniels P, Kirkland P, Carroll A, Jeggo M. The 2007 outbreak of equine influenza in Australia: lessons learned for international trade in horses.. Rev Sci Tech 2011 Apr;30(1):87-93.
    doi: 10.20506/rst.30.1.2021pubmed: 21809755google scholar: lookup
  247. Webby RJ, Webster RG, Richt JA. Influenza viruses in animal wildlife populations.. Curr Top Microbiol Immunol 2007;315:67-83.
    doi: 10.1007/978-3-540-70962-6_4pubmed: 17848061google scholar: lookup
  248. Webster RG. Are equine 1 influenza viruses still present in horses?. Equine Vet J 1993 Nov;25(6):537-8.
    doi: 10.1111/j.2042-3306.1993.tb03009.xpubmed: 8276003google scholar: lookup
  249. . Equine influenza: evolution of a highly infectious virus.. Vet Rec 2018 Jun 23;182(25):710-711.
    doi: 10.1136/vr.k2727pubmed: 29934454google scholar: lookup
  250. Wilson WD. Equine influenza.. Vet Clin North Am Equine Pract 1993 Aug;9(2):257-82.
    doi: 10.1016/S0749-0739(17)30395-4pubmed: 8358645google scholar: lookup
  251. Wise HM, Foeglein A, Sun J, Dalton RM, Patel S, Howard W, Anderson EC, Barclay WS, Digard P. A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.. J Virol 2009 Aug;83(16):8021-31.
    doi: 10.1128/JVI.00826-09pmc: PMC2715786pubmed: 19494001google scholar: lookup
  252. Wood J, Mumford J. Epidemiology of equine influenza.. Vet Rec 1992 Feb 8;130(6):126.
    doi: 10.1136/vr.130.6.126-cpubmed: 1314003google scholar: lookup
  253. Wood JM, Schild GC, Folkers C, Mumford J, Newman RW. The standardization of inactivated equine influenza vaccines by single-radial immunodiffusion.. J Biol Stand 1983 Apr;11(2):133-6.
    doi: 10.1016/S0092-1157(83)80037-7pubmed: 6408096google scholar: lookup
  254. Woodward A, Rash AS, Medcalf E, Bryant NA, Elton DM. Using epidemics to map H3 equine influenza virus determinants of antigenicity.. Virology 2015 Jul;481:187-98.
    doi: 10.1016/j.virol.2015.02.027pubmed: 25797606google scholar: lookup
  255. Woodward AL, Rash AS, Blinman D, Bowman S, Chambers TM, Daly JM, Damiani A, Joseph S, Lewis N, McCauley JW, Medcalf L, Mumford J, Newton JR, Tiwari A, Bryant NA, Elton DM. Development of a surveillance scheme for equine influenza in the UK and characterisation of viruses isolated in Europe, Dubai and the USA from 2010-2012.. Vet Microbiol 2014 Mar 14;169(3-4):113-27.
    doi: 10.1016/j.vetmic.2013.11.039pubmed: 24480583google scholar: lookup
  256. Xie T, Anderson BD, Daramragchaa U, Chuluunbaatar M, Gray GC. A Review of Evidence that Equine Influenza Viruses Are Zoonotic.. Pathogens 2016 Jul 12;5(3).
    doi: 10.3390/pathogens5030050pmc: PMC5039430pubmed: 27420100google scholar: lookup
  257. Yamanaka T, Bannai H, Nemoto M, Tsujimura K, Kondo T, Muranaka M, Hobo S, Minamijima YH, Yamada M, Matsumura T. Efficacy of a single intravenous dose of the neuraminidase inhibitor peramivir in the treatment of equine influenza.. Vet J 2012 Aug;193(2):358-62.
    doi: 10.1016/j.tvjl.2012.01.005pubmed: 22326934google scholar: lookup
  258. Yamanaka T, Cullinane A, Gildea S, Bannai H, Nemoto M, Tsujimura K, Kondo T, Matsumura T. The potential impact of a single amino-acid substitution on the efficacy of equine influenza vaccines.. Equine Vet J 2015 Jul;47(4):456-62.
    doi: 10.1111/evj.12290pubmed: 24773030google scholar: lookup
  259. Yamanaka T, Nemoto M, Bannai H, Tsujimura K, Kondo T, Matsumura T, Muranaka M, Ueno T, Kinoshita Y, Niwa H, Hidari KI, Suzuki T. No evidence of horizontal infection in horses kept in close contact with dogs experimentally infected with canine influenza A virus (H3N8).. Acta Vet Scand 2012 Apr 16;54(1):25.
    doi: 10.1186/1751-0147-54-25pmc: PMC3416777pubmed: 22506984google scholar: lookup
  260. Yamanaka T, Nemoto M, Bannai H, Tsujimura K, Kondo T, Matsumura T, Gildea S, Cullinane A. Evaluation of twenty-two rapid antigen detection tests in the diagnosis of Equine Influenza caused by viruses of H3N8 subtype.. Influenza Other Respir Viruses 2016 Mar;10(2):127-33.
    doi: 10.1111/irv.12358pmc: PMC4746556pubmed: 26568369google scholar: lookup
  261. Yamanaka T, Nemoto M, Bannai H, Tsujimura K, Kondo T, Matsumura T, Gildea S, Cullinane A. Assessment of antigenic difference of equine influenza virus strains by challenge study in horses.. Influenza Other Respir Viruses 2016 Nov;10(6):536-539.
    doi: 10.1111/irv.12418pmc: PMC5059955pubmed: 27465864google scholar: lookup
  262. Yamanaka T, Nemoto M, Bannai H, Tsujimura K, Kondo T, Matsumura T, Fu TQH, Fernandez CJ, Gildea S, Cullinane A. Rapid diagnosis of equine influenza by highly sensitive silver amplification immunochromatography system.. J Vet Med Sci 2017 Jun 16;79(6):1061-1063.
    doi: 10.1292/jvms.17-0105pmc: PMC5487783pubmed: 28458275google scholar: lookup
  263. Yamanaka T, Nemoto M, Bannai H, Tsujimura K, Matsumura T, Kokado H, Gildea S, Cullinane A. Neutralization antibody response to booster/priming immunization with new equine influenza vaccine in Japan.. J Vet Med Sci 2018 Mar 2;80(2):382-386.
    doi: 10.1292/jvms.17-0538pmc: PMC5836781pubmed: 29237998google scholar: lookup
  264. Yamanaka T, Nemoto M, Tsujimura K, Kondo T, Matsumura T. Interspecies transmission of equine influenza virus (H3N8) to dogs by close contact with experimentally infected horses.. Vet Microbiol 2009 Nov 18;139(3-4):351-5.
    doi: 10.1016/j.vetmic.2009.06.015pubmed: 19596528google scholar: lookup
  265. Yamanaka T, Niwa H, Tsujimura K, Kondo T, Matsumura T. Epidemic of equine influenza among vaccinated racehorses in Japan in 2007.. J Vet Med Sci 2008 Jun;70(6):623-5.
    doi: 10.1292/jvms.70.623pubmed: 18628606google scholar: lookup
  266. Yamanaka T, Tsujimura K, Kondo T, Matsumura T. Evaluation of antigen detection kits for diagnosis of equine influenza.. J Vet Med Sci 2008 Feb;70(2):189-92.
    doi: 10.1292/jvms.70.189pubmed: 18319581google scholar: lookup
  267. Yamanaka T, Tsujimura K, Kondo T, Matsumura T, Ishida H, Kiso M, Hidari KI, Suzuki T. Infectivity and pathogenicity of canine H3N8 influenza A virus in horses.. Influenza Other Respir Viruses 2010 Nov;4(6):345-51.
    doi: 10.1111/j.1750-2659.2010.00157.xpmc: PMC4634615pubmed: 20958928google scholar: lookup
  268. Yang H, Xiao Y, Meng F, Sun F, Chen M, Cheng Z, Chen Y, Liu S, Chen H. Emergence of H3N8 equine influenza virus in donkeys in China in 2017.. Vet Microbiol 2018 Feb;214:1-6.
    doi: 10.1016/j.vetmic.2017.11.033pubmed: 29408020google scholar: lookup
  269. Yates P, Mumford JA. Equine influenza vaccine efficacy: the significance of antigenic variation.. Vet Microbiol 2000 May 22;74(1-2):173-7.
    doi: 10.1016/S0378-1135(00)00177-2pubmed: 10799789google scholar: lookup
  270. Ye J, Xu Y, Harris J, Sun H, Bowman AS, Cunningham F, Cardona C, Yoon KJ, Slemons RD, Wan XF. Mutation from arginine to lysine at the position 189 of hemagglutinin contributes to the antigenic drift in H3N2 swine influenza viruses.. Virology 2013 Nov;446(1-2):225-9.
    doi: 10.1016/j.virol.2013.08.004pmc: PMC4161209pubmed: 24074585google scholar: lookup
  271. Yin X, Lu G, Guo W, Qi T, Ma J, Zhu C, Zhao S, Pan J, Xiang W. Identification of equine influenza virus infection in Asian wild horses (Equus przewalskii).. Arch Virol 2014 May;159(5):1159-62.
    doi: 10.1007/s00705-013-1908-zpubmed: 24212887google scholar: lookup
  272. Yondon M, Heil GL, Burks JP, Zayat B, Waltzek TB, Jamiyan BO, McKenzie PP, Krueger WS, Friary JA, Gray GC. Isolation and characterization of H3N8 equine influenza A virus associated with the 2011 epizootic in Mongolia.. Influenza Other Respir Viruses 2013 Sep;7(5):659-65.
    doi: 10.1111/irv.12069pmc: PMC3626732pubmed: 23289427google scholar: lookup
  273. Yondon M, Zayat B, Nelson MI, Heil GL, Anderson BD, Lin X, Halpin RA, McKenzie PP, White SK, Wentworth DE, Gray GC. Equine influenza A(H3N8) virus isolated from Bactrian camel, Mongolia.. Emerg Infect Dis 2014 Dec;20(12):2144-7.
    doi: 10.3201/eid2012.140435pmc: PMC4257804pubmed: 25418532google scholar: lookup

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