A preliminary study on the effect of manuka honey on second-intention healing of contaminated wounds on the distal aspect of the forelimbs of horses.
Abstract: To determine the effect of manuka honey on second-intention healing of contaminated, full-thickness skin wounds in horses. Methods: Experimental. Methods: Adult Standardbred horses (n = 8). Methods: One wound was created on the dorsomedial aspect of the third metacarpus in both forelimbs, contaminated with feces, and bandaged for 24 hours. Bandages were removed and wounds rinsed with isotonic saline solution. Wounds on 1 limb had manuka honey applied daily (n = 8) whereas wounds on the contralateral limb received no treatment (n = 8). Bandages were replaced and changed daily for 12 days, after which treatment stopped, bandages were removed, leaving wounds open to heal. Wound area was measured 24 hours after wound creation (day 1), then weekly for 8 weeks. Overall time for healing was recorded. Wound area and rate of healing of treated and control wounds were compared statistically. Results: Treatment with manuka honey decreased wound retraction and treated wounds remained significantly smaller than control wounds until day 42; however, there was no difference in overall healing time between treatment and control wounds. Conclusions: Treatment with manuka honey reduced wound area by reducing retraction but did not affect overall healing time of full-thickness distal limb wounds using this wound-healing model.
© Copyright 2011 by The American College of Veterinary Surgeons.
Publication Date: 2011-09-20 PubMed ID: 22380675DOI: 10.1111/j.1532-950X.2011.00886.xGoogle Scholar: Lookup
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- Journal Article
- Randomized Controlled Trial
Summary
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This research investigates the impact of manuka honey on the healing process of contaminated skin wounds in horses. Utilizing an experimental method involving Standardbred horses, wounds were created and treated with manuka honey in half of the instances, and observed for healing progress. Results found that while manuka honey effectively reduced the area of the wounds, it did not affect the overall healing duration.
Methods
- The study focused on full-thickness skin wounds on the forelimbs of adult Standardbred horses. Eight horses were involved in the study.
- Each horse had a wound created on the dorsomedial aspect of the third metacarpus in both forelimbs. The wounds were deliberately contaminated with feces and bandaged for 24 hours.
- After 24 hours, the bandages were removed, and the wounds were cleaned with isotonic saline solution. Manuka honey was applied daily to the wounds on one limb (eight in total), while the wounds on the opposite limb received no treatment (also eight in total).
- The bandages on the wounds were replaced daily for 12 days. After this period, treatment stopped and the bandages were removed, allowing the wounds to heal naturally.
Results
- The wounds were measured 24 hours after their creation and then weekly for eight weeks.
- The use of manuka honey was identified to minimize wound retraction, causing the treated wounds to remain significantly smaller than the untreated ones until 42 days into the study. However, there was no noticeable difference in the total healing time between the treated and untreated wounds.
Conclusion
- The research concluded that the application of manuka honey aided in reducing wound area by limiting wound retraction, and this effect persisted for a significant duration of the healing process.
- However, despite the smaller wound area, the use of manuka honey did not influence the overall healing time of the full-thickness distal limb wounds.
- This suggests that while manuka honey could be beneficial in reducing the physical damages of a wound, it does not accelerate the wound healing process in this context.
Cite This Article
APA
Bischofberger AS, Dart CM, Perkins NR, Dart AJ.
(2011).
A preliminary study on the effect of manuka honey on second-intention healing of contaminated wounds on the distal aspect of the forelimbs of horses.
Vet Surg, 40(7), 898-902.
https://doi.org/10.1111/j.1532-950X.2011.00886.x Publication
Researcher Affiliations
- Biomedical Research and Clinical Trials Unit, University Veterinary Teaching Hospital, University of Sydney, Camden, Australia.
MeSH Terms
- Animals
- Forelimb
- Honey
- Horse Diseases / therapy
- Horses
- Male
- Time Factors
- Wound Healing
- Wounds and Injuries / therapy
- Wounds and Injuries / veterinary
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