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A retrospective study of equine actinobacillosis cases: 1999-2011.

Abstract: Several Actinobacillus spp. are common commensal bacteria of the oral cavity, gastrointestinal tract, and reproductive tract of horses and can cause disease in both foals and adults. The current retrospective study was designed to review Actinobacillus spp. isolated from clinical samples or necropsies of 99 horses during 1999-2011. The cases consisted of 43 foals (2 years of age), 2 aborted fetuses, and 11 with unspecified ages. Clinical history, signs, bacterial species isolated, and associated lesions were documented. Actinobacillus spp. were isolated 111 times. The most common isolates were Actinobacillus equuli subsp. equuli (38.7%) and hemolytic Actinobacillus spp. (24.3%). Other isolates were Actinobacillus lignieresii (5.4%), Actinobacillus pleuropneumoniae (1.8%), and unclassified Actinobacillus spp. (28.8%). Actinobacillus equuli subsp. equuli was most commonly isolated from clinical and necropsy cases of septicemia and respiratory disease in both foals and adults. Embolic nephritis, the classical septicemic lesion of equine neonatal actinobacillosis, was also present in several adult septicemic actinobacillosis cases. Predisposing factors such as failure of passive transfer of colostral antibodies as well as concurrent pathogenic bacterial or viral infections were present in numerous actinobacillosis cases. There were many cases, however, for which a predisposing factor or concurrent infection was not documented or apparent, suggesting that Actinobacillus spp. can be primary pathogens under the right circumstances and in the right location.
Publication Date: 2014-04-17 PubMed ID: 24742921DOI: 10.1177/1040638714531766Google Scholar: Lookup
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  • Journal Article

Summary

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This retrospective study investigates the presence and impact of Actinobacillus bacteria in horses over a 12-year period, noting its association with diseases like septicemia and respiratory illness in both foals and adults.

Study Background

  • Actinobacillus is a type of bacteria often found in a horse’s oral cavity, gastrointestinal tract, and reproductive tract. While it is usually harmless, under certain conditions it can cause disease.
  • This study is a retrospective look at Actinobacillus occurrences in horses from 1999 to 2011. It aimed to review the types of Actinobacillus bacteria isolated and the clinical history, signs, and associated pathologies of the affected horses.

Study Sample

  • The study observed 99 horses of various age groups, including 43 foals, 4 young adults, 39 adults, 2 aborted fetuses, and 11 horses of unspecified ages.

Bacterial Strains and Disease

  • Actinobacillus bacteria were isolated from the horses 111 times on separate occasions. The most common types identified were Actinobacillus equuli subsp. equuli, and hemolytic Actinobacillus spp.
  • The bacteria were often associated with conditions like septicemia (blood poisoning) and respiratory disease in both foals and adult horses. Septicemia was associated with embolic nephritis, a form of kidney inflammation, in neonatal and some adult horses.

Predisposing Factors

  • Foals are particularly at risk if they have failed to properly absorb antibodies from their mothers’ milk.
  • Sometimes other pathogenic bacteria or viral infections were present alongside Actinobacillus, indicating these could be contributing factors to developing disease.

Findings and Suggestions

  • However, in many cases, no other infections or predisposing factors were documented, suggesting that Actinobacillus bacteria can act as primary pathogens, causing disease on their own under the right conditions.

Cite This Article

APA
Layman QD, Rezabek GB, Ramachandran A, Love BC, Confer AW. (2014). A retrospective study of equine actinobacillosis cases: 1999-2011. J Vet Diagn Invest, 26(3), 365-375. https://doi.org/10.1177/1040638714531766

Publication

ISSN: 1943-4936
NlmUniqueID: 9011490
Country: United States
Language: English
Volume: 26
Issue: 3
Pages: 365-375

Researcher Affiliations

Layman, Quinci D
  • Oklahoma State University, Center of Veterinary Health Sciences, Department of Veterinary Pathobiology (Layman, Confer), Stillwater, OKOklahoma Animal Disease Diagnostic Laboratory (Rezabek, Ramachandran, Love), Stillwater, OK.
Rezabek, Grant B
  • Oklahoma State University, Center of Veterinary Health Sciences, Department of Veterinary Pathobiology (Layman, Confer), Stillwater, OKOklahoma Animal Disease Diagnostic Laboratory (Rezabek, Ramachandran, Love), Stillwater, OK.
Ramachandran, Akhilesh
  • Oklahoma State University, Center of Veterinary Health Sciences, Department of Veterinary Pathobiology (Layman, Confer), Stillwater, OKOklahoma Animal Disease Diagnostic Laboratory (Rezabek, Ramachandran, Love), Stillwater, OK.
Love, Brenda C
  • Oklahoma State University, Center of Veterinary Health Sciences, Department of Veterinary Pathobiology (Layman, Confer), Stillwater, OKOklahoma Animal Disease Diagnostic Laboratory (Rezabek, Ramachandran, Love), Stillwater, OK.
Confer, Anthony W
  • Oklahoma State University, Center of Veterinary Health Sciences, Department of Veterinary Pathobiology (Layman, Confer), Stillwater, OKOklahoma Animal Disease Diagnostic Laboratory (Rezabek, Ramachandran, Love), Stillwater, OK anthony.confer@okstate.edu.

Citations

This article has been cited 9 times.
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