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A serological survey of pigs, horses, and ducks in Nepal for evidence of infection with Japanese encephalitis virus.
Abstract: Japanese encephalitis (JE) is an emerging disease of animals and humans in Nepal. A serological study for antibody to JE virus was conducted in Nepal from September 2003 to August 2004 by collecting 280 sera from pigs, ducks, and horses covering 10 districts of the country. These sera were tested by performing competitive enzyme-linked immunosorbent assay for the detection of antibodies against JE virus. The total number of tested sera was 280, of which 43.92% were found positive for the presence of antibodies against JE virus infection in Nepal. Sero-prevalence of JE in pigs, ducks, and horses was 48.11%, 26.79%, and 50.0%, respectively.
Publication Date: 2006-12-01 PubMed ID: 17135501DOI: 10.1196/annals.1373.013Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research examined the occurrence of the Japanese Encephalitis virus in animals in different regions of Nepal by testing their antibodies. The study found that out of the 280 animals tested (comprised of pigs, ducks, and horses), nearly half exhibited signs of infection.
Objective of the Research
- The aim of this research was to ascertain the prevalence of the Japanese Encephalitis (JE) virus among animals in Nepal, including pigs, ducks and horses, which could facilitate further understanding of the disease transmission to humans.
Sampling and Data Collection
- This study was conducted from September 2003 to August 2004 in 10 districts of Nepal.
- A total of 280 blood samples were collected from three types of animals: pigs, ducks, and horses.
- The samples were then tested using a competitive enzyme-linked immunosorbent assay (ELISA) which can identify the presence of antibodies against the JE virus, indicating the animal’s exposure to the virus.
Results of the Study
- The results indicated that approximately 44% of the total samples tested positive for the presence of JE virus antibodies.
- When broken down by animal type, roughly 48% of pig samples, 27% of duck samples, and 50% of horse samples had antibodies against the JE virus. This implies that these animals had been infected with the virus at some point.
Significance of the Research
- This research is of importance because it highlights a high prevalence of the JE virus among animals in Nepal, suggesting that it is an emerging disease in this region.
- The diverse range of animal hosts increases the risks of the virus spilling over into human populations, particularly in rural and farming communities, and therefore has significant implications for human health.
Cite This Article
APA
Pant GR.
(2006).
A serological survey of pigs, horses, and ducks in Nepal for evidence of infection with Japanese encephalitis virus.
Ann N Y Acad Sci, 1081, 124-129.
https://doi.org/10.1196/annals.1373.013 Publication
Researcher Affiliations
- Central Veterinary Laboratory, Tripureshwor, Kathmandu, Nepal. ganeshrajpant@yahoo.co.uk
MeSH Terms
- Animals
- Antibodies, Viral / blood
- Ducks
- Encephalitis Virus, Japanese / immunology
- Encephalitis, Japanese / epidemiology
- Encephalitis, Japanese / veterinary
- Enzyme-Linked Immunosorbent Assay / methods
- Enzyme-Linked Immunosorbent Assay / veterinary
- Horse Diseases / epidemiology
- Horses
- Nepal / epidemiology
- Poultry Diseases / epidemiology
- Seroepidemiologic Studies
- Swine
- Swine Diseases / epidemiology
Citations
This article has been cited 17 times.- Ladreyt H, Auerswald H, Tum S, Ken S, Heng L, In S, Lay S, Top C, Ly S, Duong V, Dussart P, Durand B, Chevalier V. Comparison of Japanese Encephalitis Force of Infection in Pigs, Poultry and Dogs in Cambodian Villages. Pathogens 2020 Sep 1;9(9).
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- Auerswald H, Ruget AS, Ladreyt H, In S, Mao S, Sorn S, Tum S, Duong V, Dussart P, Cappelle J, Chevalier V. Serological Evidence for Japanese Encephalitis and West Nile Virus Infections in Domestic Birds in Cambodia. Front Vet Sci 2020;7:15.
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- Ladreyt H, Durand B, Dussart P, Chevalier V. How Central Is the Domestic Pig in the Epidemiological Cycle of Japanese Encephalitis Virus? A Review of Scientific Evidence and Implications for Disease Control. Viruses 2019 Oct 15;11(10).
- Lee HS, Thanh TL, Ly NK, Nguyen-Viet H, Thakur KK, Grace D. Seroprevalence of leptospirosis and Japanese encephalitis in swine in ten provinces of Vietnam. PLoS One 2019;14(8):e0214701.
- Karna AK, Bowen RA. Experimental Evaluation of the Role of Ecologically-Relevant Hosts and Vectors in Japanese Encephalitis Virus Genotype Displacement. Viruses 2019 Jan 6;11(1).
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