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Comparative immunology, microbiology and infectious diseases1982; 5(1-3); 139-141; doi: 10.1016/0147-9571(82)90027-3

A summary of antibody titration experiments in some animal species treated with ERA vaccine and an inactivated rabies vaccine.

Abstract: The results of antibody titrations in different animal species vaccinated against rabies are reported. The following points are considered: (1) antibody titration may be used to detect an immunity status in dogs, (2) equines should be vaccinated in infected areas, (3) experiments in progress are comparing ERA vaccine and an inactivated vaccine in bovines, and (4) the vaccination of fallow deer (Dama dama) and moufflons (Ovis ammon musimon) produced results suggesting an extension of the experiment with the purpose of vaccinating wild ruminants whenever possible.
Publication Date: 1982-01-01 PubMed ID: 7128062DOI: 10.1016/0147-9571(82)90027-3Google Scholar: Lookup
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  • Comparative Study
  • Journal Article

Summary

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This research article primarily focuses on the results of antibody titration experiments conducted in various animal species that were vaccinated against rabies. The research suggests that these titrations can be used to monitor immunity status in dogs, equines should be vaccinated in infected areas, and give preliminary findings on the comparison between two types of vaccines in bovines, while also discussing the effectiveness of vaccination in wild ruminants.

Antibody titration to determine immunity status in dogs

  • One of the key findings of the research is that the level of antibodies, determined through titration, can be effectively used to verify the immunity status of dogs against rabies. This means that by running titration tests in dogs, it is possible to determine whether the rabies vaccine has effectively worked in producing an immunological response in the organism, thus providing protection against the disease.

Significance of vaccinating equines in infected areas

  • The research also underscored the importance of vaccinating equines in areas where there’s a prevalence of rabies infection. The reason for this is likely attributed to the susceptibility of these animals to rabies, and the potential risk they could pose in spreading the disease in regions where the disease is endemic.

Comparison of ERA vaccine and inactivated vaccine in bovines

  • A significant part of the research is dedicated to comparing the effectiveness of the Street Alabama Dufferin (ERA) vaccine and an inactivated rabies vaccine in bovines. While the article does not conclusively suggest one over the other, it points out that the experiments comparing both are in progress. This comparison is of primary importance, given that the results may contribute to the selection of a more effective vaccine for bovines in future.

Vaccination of wild ruminants

  • The research also includes results of rabies vaccination in fallow deer and moufflons. The positive results observed in these cases suggest the possibility of extending these vaccination trials to include other species of wild ruminants whenever possible. As such, this could serve as an effective strategy to control rabies infections in the wider animal kingdom – especially the wild ones, where treatment and control of diseases are typically more challenging.

Cite This Article

APA
Mantovani A, Caporale V, Ciuchini F, Di Trani L, Irsara A, Prosperi S. (1982). A summary of antibody titration experiments in some animal species treated with ERA vaccine and an inactivated rabies vaccine. Comp Immunol Microbiol Infect Dis, 5(1-3), 139-141. https://doi.org/10.1016/0147-9571(82)90027-3

Publication

ISSN: 0147-9571
NlmUniqueID: 7808924
Country: England
Language: English
Volume: 5
Issue: 1-3
Pages: 139-141

Researcher Affiliations

Mantovani, A
    Caporale, V
      Ciuchini, F
        Di Trani, L
          Irsara, A
            Prosperi, S

              MeSH Terms

              • Animals
              • Animals, Wild
              • Antibody Formation
              • Cattle
              • Deer
              • Dogs
              • Horses
              • Rabies / prevention & control
              • Rabies Vaccines / immunology
              • Species Specificity

              Citations

              This article has been cited 1 times.
              1. Prosperi S, Irsara A, Battelli G, Sanguinetti V. Vaccination of cattle with live and inactivated rabies vaccines: a study of antibody response.. Vet Res Commun 1984 Aug;8(3):181-5.
                doi: 10.1007/BF02214710pubmed: 6495634google scholar: lookup