[Activities of the enzymes LDH, gamma-GT, GOT, GPT and lactoperoxidase in the milk of breeding mares during the course of lactation].
Abstract: Milk samples were collected from 44 mares (trotters, warm blood horses, quarter horses) during lactation between the 1st and 90th day p.p. at 20 defined days. The activity of the enzymes LDH, gamma-GT, GOT, GPT and lactoperoxidase was investigated. The aim of this study was to find out the changes of these parameters during lactation and whether an influence of race, conception, date of foaling, age and number of lactations existed on the enzyme activities in mare's milk. The following results were obtained: In mare's milk the LDH-activity was highest (xg = 629 x 1.5 +/- 1 U/l) on the 1st day p.p. and showed a marked decrease on the 3rd day p.p. followed by a slight decrease until the 20th day p.p. It remained then at a constant level of about 80 U/l. The lowest activity (xg = 65.2 x 1.51 +/- 1 U/l) was measured on the 76th day p.p. The influence of conception and date of foaling time were statistically significant. The gamma-GT-activity was highest on the 3rd day p.p. (xg = 143.4 x 1.45 +/- 1 U/L) and decreased during lactation. The lowest activity was measured on the 90th day p.p. (xg = 23.2 x 1.51 +/- 1 U/L). The influence of race and conception--time were statistically significant. The GOT-activity of the 1st day p.p. (xg = 38.3 x 1.77 +/- 1 U/L) was higher than in mature milk. After the 3rd day p.p. activities between 15.5 x 1.38 +/- 1 U/l and 11.9 x 1.38 +/- 1 U/L were measured. The GPT-activity was highest on the 1st day p.p. (xg = 37.5 x 1.81 +/- 1 U/L) and decreased on the following days. After the 9th day p.p. activities between 9.1 x 1.37 +/- 1 U/l and 8.5 x 1.32 +/- 1 U/l were found. The influence of age, race, race (time, date of foaling (time and conception (time were significant. No Lactoperoxidase activity could be found in mare's milk. The origin and importance of the mare's milk enzymes are discussed.
Publication Date: 1998-05-16 PubMed ID: 9542806
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- English Abstract
- Journal Article
Summary
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The research paper investigates the activities of certain enzymes in the milk of breeding horses during lactation. The main goal was to discover any changes in these enzyme parameters during lactation, and potential effects from factors such as breed, conception, and lactation number.
Enzymes Investigated
- LDH (lactate dehydrogenase)
- GOT (aspartate aminotransferase)
- GPT (alanine transaminase)
- Gamma-GT (gamma-glutamyltransferase)
- Lactoperoxidase
Research Methodology
Milk samples were collected from 44 mares, which included trotters, warm blood horses, and quarter horses. Collection took place over a 90 day lactation period at 20 specific elapsed durations.
Research Results
- LDH activity was highest on the 1st day postpartum (p.p.), decreased noticeably by the 3rd day p.p., and then declined slightly up until the 20th day p.p. Afterward, it remained consistent at around 80 U/l. The lowest activity was observed on day 76 p.p.
- The activity of gamma-GT reached its peak on day 3 p.p. and steadily declined during lactation. The lowest detection of gamma-GT was on day 90 p.p.
- GOT activity was highest on day 1 p.p., but values recorded after day 3 p.p. revealed fluctuating and generally lower measurements.
- GPT activity, like GOT and LDH, was highest on day 1 p.p. and declined in the days that followed. Beyond day 9 p.p., a narrow activity range was observed.
- No lactoperoxidase activity was found in the mare’s milk.
Statistical Significance
The results showed that various factors had a significant impact on enzyme activity in the milk, including breed, date of foaling, conception, age, and number of lactations. The study sheds light on how these factors influence enzyme activity during lactation in horses and how this could possibly affect the nutritional quality of the milk. However, the study does not delve into the implications of these results, ending instead with a discussion on the origin and importance of the enzymes in mare’s milk.
Cite This Article
APA
Rieland E, Hatzipanagiotou A, Jahnecke S, Enbergs H.
(1998).
[Activities of the enzymes LDH, gamma-GT, GOT, GPT and lactoperoxidase in the milk of breeding mares during the course of lactation].
Berl Munch Tierarztl Wochenschr, 111(3), 81-89.
Publication
Researcher Affiliations
- Institut für Anatomie, Physiologie und Hygiene, Haustiere der Universität Bonn.
MeSH Terms
- Alanine Transaminase / metabolism
- Animals
- Aspartate Aminotransferases / metabolism
- Female
- Horses
- L-Lactate Dehydrogenase / metabolism
- Lactation / physiology
- Lactoperoxidase / metabolism
- Milk / enzymology
- Time Factors
- gamma-Glutamyltransferase / metabolism
Citations
This article has been cited 2 times.- Singh P, Hernandez-Rauda R, Peña-Rodas O. Preventative and therapeutic potential of animal milk components against COVID-19: A comprehensive review. Food Sci Nutr 2023 Jun;11(6):2547-2579.
- Shokrollahi B, Choi JY, Won M, Kim ET, Lee SE, Ham JS. Koumiss (Fermented Mare's Milk) as a Functional Food: Bioactive Proteins, Peptides, and Future Perspectives. Foods 2025 Nov 18;14(22).
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