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Alleviation of postanesthetic hypoxemia in the horse.

Abstract: This study was designed to investigate the effect of the nasotracheal insufflation of oxygen at a flow rate of 15 L/min on the arterial partial pressure of oxygen during the recovery period following inhalation anesthesia in the horse. It has been stated that this is a suitable flow rate to prevent postoperative hypoxemia but without any experimental evidence to support those statements. Horses being used for the study of healing of cartilage were anesthetized on two separate occasions. Following one period of anesthesia they were allowed to recover breathing room air, and following the other period of anesthesia oxygen was insufflated into the trachea at 15 L/min throughout the recovery period. This permitted each horse to act as its own control and allowed statistical analysis using Student's t-test for paired samples.The insufflated horses had a higher arterial partial pressure of oxygen during the recovery period than did the noninsufflated horses (p < 0.05).
Publication Date: 1989-01-01 PubMed ID: 17423205PubMed Central: PMC1680984
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  • Journal Article

Summary

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This research sought to understand the impact of nasotracheal oxygen insufflation, with a flow rate of 15 L/min, on the arterial oxygen partial pressure during post-anesthesia recovery in horses.

Study Design

  • The study was designed to examine how the insufflation of oxygen, at a 15 L/min flow rate, into a horse’s nasotrachea affects the partial pressure of oxygen in arterial blood during the recovery period following inhalation anesthesia.
  • This flow rate was identified as a potential solution to prevent postoperative hypoxemia, even though there wasn’t sufficient experimental evidence to corroborate this claim.

Research Methodology

  • Horses used in a healing of cartilage study were selected to be part of the experiment. They were anesthetized twice.
  • In the first scenario, the horses were allowed to recover from anesthesia by breathing room air.
  • For the second scenario, oxygen was insufflated into the trachea of the horses at a rate of 15 L/min during the recovery period.
  • The experiment was structured to ensure that each horse acted as its own control. This means the outcomes of the oxygen insufflation during recovery were measured against the recovery where the horses just inhaled room air.

Statistical Analysis & Results

  • The data gathered during the experiment underwent statistical analysis using the Student’s t-test for paired samples.
  • This analysis showed a significant increase in the arterial partial pressure of oxygen in the horses that were insufflated with oxygen during the recovery period, in comparing with the horses that weren’t (p-value < 0.05).

Conclusions

  • The research provides experimental evidence to support the claim that nasotracheal insufflation of oxygen at a flow rate of 15 L/min can prevent postoperative hypoxemia in horses.
  • As a result, the use of oxygen insufflation at this flow rate could be adopted in veterinary practice to ensure a safer recovery from inhalation anesthesia.

Cite This Article

APA
McMurphy RM, Cribb PH. (1989). Alleviation of postanesthetic hypoxemia in the horse. Can Vet J, 30(1), 37-41.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 30
Issue: 1
Pages: 37-41

Researcher Affiliations

McMurphy, R M
    Cribb, P H

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      Citations

      This article has been cited 5 times.
      1. Kälin I, Henze IS, Ringer SK, Torgerson PR, Bettschart-Wolfensberger R. Comparison of Recovery Quality Following Medetomidine versus Xylazine Balanced Isoflurane Anaesthesia in Horses: A Retrospective Analysis.. Animals (Basel) 2021 Aug 19;11(8).
        doi: 10.3390/ani11082440pubmed: 34438896google scholar: lookup
      2. Stefanik E, Drewnowska O, Lisowska B, Turek B. Causes, Effects and Methods of Monitoring Gas Exchange Disturbances during Equine General Anaesthesia.. Animals (Basel) 2021 Jul 9;11(7).
        doi: 10.3390/ani11072049pubmed: 34359177google scholar: lookup
      3. Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature.. Animals (Basel) 2021 Jun 14;11(6).
        doi: 10.3390/ani11061777pubmed: 34198637google scholar: lookup
      4. Cerullo M, Driessen B, Douglas H, Hopster K. Changes in Arterial Blood Pressure and Oxygen Tension as a Result of Hoisting in Isoflurane Anesthetized Healthy Adult Horses.. Front Vet Sci 2020;7:601326.
        doi: 10.3389/fvets.2020.601326pubmed: 33324704google scholar: lookup
      5. Dupont J, Serteyn D, Sandersen C. Prolonged Recovery From General Anesthesia Possibly Related to Persistent Hypoxemia in a Draft Horse.. Front Vet Sci 2018;5:235.
        doi: 10.3389/fvets.2018.00235pubmed: 30327770google scholar: lookup