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Journal of equine veterinary science2022; 112; 103914; doi: 10.1016/j.jevs.2022.103914

An Analysis of Risk Factors for a Fracture or Luxation in Recovery From General Anesthesia in Horses: A Single Centre Study☆.

Abstract: Catastrophic fractures or luxations (FoL) sustained during recovery from general anesthesia are a significant cause of mortality during equine anesthesia. There is a lack of evidence regarding potential risk factors for a FoL occurring in the immediate anesthetic recovery period. A single center, retrospective, case-matched study was performed to identify risk factors for sustaining a catastrophic FoL during recovery from general anesthesia. Clinical data were obtained for horses which sustained a catastrophic FoL when recovering from general anesthesia from January 2011 to June 2020 in a single center referral population. Multivariable logistical regression analysis was performed to identify risk factors which were significant in horses where a FoL occurred. Statistically significant risk factors in our population of horses of sustaining a FoL in recovery included intraoperative administration of intratracheal salbutamol, intraoperative administration of ketamine and increasing age. Further research in this area, particularly with regards to salbutamol administration, is required.
Publication Date: 2022-02-23 PubMed ID: 35218904DOI: 10.1016/j.jevs.2022.103914Google Scholar: Lookup
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  • Journal Article

Summary

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This research investigates the risk factors associated with horses experiencing severe fractures or joint dislocations during recovery from general anesthesia. It found that intraoperative administration of salbutamol and ketamine, along with increasing age, heightened this risk.

Research Objective

  • The primary objective of this study was to identify the potential risk factors that increase the likelihood of horses suffering from catastrophic fractures or luxations (FoL) during recovery from general anesthesia.

Methodology

  • The study was executed as a single center, retrospective, case-matched study.
  • Clinical data were collected from January 2011 to June 2020 for horses that had experienced a FoL while recovering from anesthesia at a single center referral population.
  • To identify the significant risk factors that could be associated with a FoL occurrence, a multivariable logistic regression analysis was carried out.

Key Findings

  • The risk factors found to be statistically significant in increasing the chances of sustaining a FoL during recovery were the intraoperative administration of intratracheal salbutamol and ketamine, and increasing age.

Implications

  • The research findings suggest that more caution should be applied when using intratracheal salbutamol and ketamine during surgery, especially in older horses.
  • Further research is needed to better understand the specific role salbutamol administration plays in increasing this risk.

Cite This Article

APA
Bennell AJ, Wright RJH, Malalana F, Senior JM. (2022). An Analysis of Risk Factors for a Fracture or Luxation in Recovery From General Anesthesia in Horses: A Single Centre Study☆. J Equine Vet Sci, 112, 103914. https://doi.org/10.1016/j.jevs.2022.103914

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 112
Pages: 103914

Researcher Affiliations

Bennell, Alison Joan
  • School of Veterinary Science, University of Liverpool, Neston, Cheshire, UK. Electronic address: bennell@liverpool.ac.uk.
Wright, Rowan James Harris
  • School of Veterinary Science, University of Liverpool, Neston, Cheshire, UK.
Malalana, Fernando
  • School of Veterinary Science, University of Liverpool, Neston, Cheshire, UK.
Senior, Jonathan Mark
  • School of Veterinary Science, University of Liverpool, Neston, Cheshire, UK.

MeSH Terms

  • Albuterol / therapeutic use
  • Anesthesia Recovery Period
  • Anesthesia, General / adverse effects
  • Anesthesia, General / veterinary
  • Animals
  • Horses
  • Retrospective Studies
  • Risk Factors