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Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2010; 20(6); 616-622; doi: 10.1111/j.1476-4431.2010.00586.x

Anaphylaxis and systemic inflammatory response syndrome induced by inadvertent intravenous administration of mare’s milk in a neonatal foal.

Abstract: To describe the diagnostic procedures, therapeutic management and successful outcome of a case of anaphylaxis induced by the inadvertent intravenous (IV) administration of mare's milk to a neonatal foal. Methods: A 3-day-old Thoroughbred colt was presented for treatment of bilateral flexural limb deformities of the forelimbs. Because the foal was unable to ambulate initially, mare's milk was administered via nasoesophageal tube feedings during treatment of the musculoskeletal disorder. Anaphylaxis resulted after unintentional administration of a bolus of 150mL of mare's milk through a jugular catheter. Aggressive therapy for anaphylaxis and careful monitoring resulted in the successful recovery of the foal after 9 days of intensive care. Conclusions: This case is the first published report to describe the effects of accidental IV administration of mare's milk to a neonatal foal. Medical errors are commonly reported in pediatric medicine; the intent of this report is to raise awareness of medical errors and student education in equine medicine as well as describe the therapy and outcome of anaphylaxis induced by IV administration of mare's milk in a neonatal foal.
Publication Date: 2010-10-07 PubMed ID: 21166984DOI: 10.1111/j.1476-4431.2010.00586.xGoogle Scholar: Lookup
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Summary

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This research article details a case where a newborn horse experienced a severe allergic reaction after milk was accidentally injected into its veins, and how its subsequent treatment led to recovery. The case also underscores the importance of education and vigilance in preventing medical errors in veterinary medicine.

Background

The subject of the study is a three-day-old Thoroughbred colt that was presented for treatment due to bilateral flexural limb deformities. Because the newborn horse was unable to move, it was fed mare’s milk via a tube going through its nose and into its esophagus. However, an unintentional error led to the administration of mare’s milk into the foal’s jugular vein, triggering an anaphylactic reaction.

  • Anaphylaxis is a severe and often sudden allergic reaction, which can be life threatening and demands immediate medical intervention.
  • Administering mare’s milk – intended as a nutritional supplementation – directly into the blood stream instead of the digestive tract is highly irregular, causing the unusual reaction.

Case Description and Treatment

After being given the milk intravenously, the foal showed symptoms of anaphylaxis. The researchers then started an aggressive therapy regimen for treating the foal’s severe allergic reaction.

  • The therapy involved continual monitoring and intense care over a period of nine days.
  • Despite the initial adversity, the foal eventually recovered from the anaphylaxis brought on by the unintended medical error.

Significance and Implications

This research case illustrates the potential hazards of medical errors and underscores the need for improved student education in equine medicine.

  • The study is unique as it is the first to document the effects of intravenous administration of mare’s milk in foal, an event that is seldom encountered in veterinary practice.
  • By presenting the successful outcome, the case serves as a guide in treating similar medical mishaps.
  • Medical errors are not uncommon in pediatric medicine, both human and veterinary. Hence, this report also serves as a reminder of the need for increased vigilance and caution when treating young patients.

Cite This Article

APA
Alcott CJ, Wong DM. (2010). Anaphylaxis and systemic inflammatory response syndrome induced by inadvertent intravenous administration of mare’s milk in a neonatal foal. J Vet Emerg Crit Care (San Antonio), 20(6), 616-622. https://doi.org/10.1111/j.1476-4431.2010.00586.x

Publication

ISSN: 1476-4431
NlmUniqueID: 101152804
Country: United States
Language: English
Volume: 20
Issue: 6
Pages: 616-622

Researcher Affiliations

Alcott, Cody J
  • Lloyd Veterinary Medical Center, College of Veterinary Medicine, Iowa State University, Ames, IA 50011-1250, USA. cjalcott@iastate.edu
Wong, David M

    MeSH Terms

    • Anaphylaxis / etiology
    • Anaphylaxis / therapy
    • Anaphylaxis / veterinary
    • Animals
    • Animals, Suckling
    • Forelimb / abnormalities
    • Horse Diseases / etiology
    • Horse Diseases / therapy
    • Horses / abnormalities
    • Infusions, Intravenous / adverse effects
    • Infusions, Intravenous / veterinary
    • Medication Errors / veterinary
    • Milk / adverse effects
    • Systemic Inflammatory Response Syndrome / etiology
    • Systemic Inflammatory Response Syndrome / therapy
    • Systemic Inflammatory Response Syndrome / veterinary
    • Treatment Outcome

    Citations

    This article has been cited 1 times.
    1. Basile RC, Rivera GG, Del Rio LA, de Bonis TC, do Amaral GP, Giangrecco E, Ferraz G, Yoshinari NH, Canola PA, Queiroz Neto A. Anaphylactoid reaction caused by sodium ceftriaxone in two horses experimentally infected by Borrelia burgdorferi. BMC Vet Res 2015 Aug 12;11:197.
      doi: 10.1186/s12917-015-0478-6pubmed: 26265349google scholar: lookup