Anthelmintic efficacy fenbendazole paste in equines.
Abstract: A single oral dose of fenbendazole (FBZ) paste at 7,5 mg/kg body mass was given to 5 horses. It was highly effective against adults of the following genera: Cyathostomum, Cylicostephanus, Cylicondontophorus, Poteriostomum, Cylicocyclus, Triodontophorus, Oesophagodontus (and other genera belonging to the subfamily Cyathostominae). Similarly, high efficacy was obtained against the adults of the following species: Oxyuris equi, Strongylus vulgaris, Strongylus equinus and Probstmayria vivipara. These results were confirmed in 12 horses and in addition FBZ at 7,5 mg/kg was highly effective against Parascaris equorum, Craterostomum and Gyalocephalus.
Publication Date: 1981-06-01 PubMed ID: 7277372
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- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research examined the effectiveness of fenbendazole (a medication) in treating various species of equine (horse) intestinal worms.
Objective of the Research
The main objective of the research was to evaluate the efficacy of a single oral dose of fenbendazole paste, at 7.5 mg/kg of a horse’s body mass, against various types of intestinal worms found in equines.
Methodology
- The research was carried out on 5 horses initially.
- Each of the horses was administered a single oral dose of fenbendazole paste at 7.5 mg/kg body mass.
- The effectiveness of this medication was then assessed against adult intestinal worms of various genera including Cyathostomum, Cylicostephanus, Cylicondontophorus, Poteriostomum, Cylicocyclus, Triodontophorus, Oesophagodontus and others belonging to the subfamily Cyathostominae.
- The efficacy of the medication against adults of specific worm species, namely, Oxyuris equi, Strongylus vulgaris, Strongylus equinus and Probstmayria vivipara was also evaluated.
Results
- The study found that fenbendazole was highly effective against the adult worms of the various genera mentioned above.
- Similarly, it showed high efficacy against adults of the specific worm species including Oxyuris equi, Strongylus vulgaris, Strongylus equinus and Probstmayria vivipara.
- These results were further confirmed in an additional sample of 12 horses.
- In the larger sample, fenbendazole was also found to be highly effective against additional worm species: Parascaris equorum, Craterostomum and Gyalocephalus.
This research establishes fenbendazole as a highly effective medication for controlling various species of intestinal worms in horses.
Cite This Article
APA
Malan FS, Reinecke RK, Scialdo RC.
(1981).
Anthelmintic efficacy fenbendazole paste in equines.
J S Afr Vet Assoc, 52(2), 127-130.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Benzimidazoles / administration & dosage
- Drug Evaluation
- Feces / parasitology
- Fenbendazole / administration & dosage
- Horse Diseases / drug therapy
- Horse Diseases / parasitology
- Horses
- Intestines / parasitology
- Nematode Infections / drug therapy
- Nematode Infections / veterinary
- Parasite Egg Count
- Stomach / parasitology
Citations
This article has been cited 2 times.- Lind EO, Kuzmina T, Uggla A, Waller PJ, Höglund J. A field study on the effect of some anthelmintics on cyathostomins of horses in sweden. Vet Res Commun 2007 Jan;31(1):53-65.
- Hamad MH, Islam SI, Jitsamai W, Chinkangsadarn T, Naraporn D, Ouisuwan S, Taweethavonsawat P. Patterns of Equine Small Strongyle Species Infection after Ivermectin Intervention in Thailand: Egg Reappearance Period and Nemabiome Metabarcoding Approach. Animals (Basel) 2024 Feb 8;14(4).
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