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Anthelmintic efficiency of fenbendazole in equines.

Abstract: A single oral dose of fenbendazole (FBZ) at 10mg/kg body mass was given to 5 donkeys. A further 5 donkeys were dosed with a medicated lick (1 mg FBZ/g lick) until the oral consumption was 10mg/kg body mass. In both trials FBZ was highly effective against adults of the following genera: Cyathostomum, Cylicocyelus, Cylicostephanus, Cylicodontophorus, Poteriostomum, Cabellonema, Craterostomum and Triodontophorus; similarly high efficiency was obtained against the following species: Habronema majus, Habronema musca, Strongylus vulgaris and Oxyuris equi and worms identified as belonging to the subfamily Cyathostostominae. These results were confirmed in horses and in addition FBZ at 10mg/kg was highly effective against Gyalocephalus capitatus, Oesophagodontos robustus and Parascaris equorum.
Publication Date: 1980-12-01 PubMed ID: 7241490
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  • Journal Article

Summary

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This research article explores the effectiveness of a drug named fenbendazole, used against certain types of internal parasites (helminths) in equines. The study found that a single dose of fenbendazole was highly effective against numerous genera and species of these parasites, in both donkeys and horses.

Study Design and Methodology

  • The research involved an examination of the anthelmintic efficiency of fenbendazole on horses and donkeys.
  • Two separate trials were conducted. In the first, five donkeys were given a single oral dose of fenbendazole at a dose of 10mg/kg body mass. In the second trial, another five donkeys were treated with a medicated lick, containing 1 mg of fenbendazole per gram, until the overall oral consumption was equivalent to 10mg/kg body mass.

Results

  • Both methodologies demonstrated high degrees of effectiveness for fenbendazole against various types of adult helminth parasites.
  • The medication was effective against helminths of several genera, including Cyathostomum, Cylicocyelus, Cylicostephanus, Cylicodontophorus, Poteriostomum, Cabellonema, Craterostomum and Triodontophorus.
  • Likewise, the drug showed a similarly high efficiency against certain species in particular, which included Habronema majus, Habronema musca, Strongylus vulgaris and Oxyuris equi, as well as worms identified as belonging to the subfamily Cyathostostominae.
  • In horses, in addition to the successful results found in donkeys, fenbendazole was also highly effective against other species, specifically Gyalocephalus capitatus, Oesophagodontos robustus and Parascaris equorum.

Implications of the Study

  • The study confirms the efficacy of fenbendazole treatment in equines for several types of helminth infections.
  • These results can help inform better practices for equine health and wellbeing, through the effective control and management of internal parasites.

Cite This Article

APA
Malan FS, Reinecke RK. (1980). Anthelmintic efficiency of fenbendazole in equines. J S Afr Vet Assoc, 51(4), 223-226.

Publication

ISSN: 1019-9128
NlmUniqueID: 7503122
Country: South Africa
Language: English
Volume: 51
Issue: 4
Pages: 223-226

Researcher Affiliations

Malan, F S
    Reinecke, R K

      MeSH Terms

      • Animals
      • Benzimidazoles / therapeutic use
      • Feces / parasitology
      • Fenbendazole / therapeutic use
      • Helminthiasis / drug therapy
      • Helminthiasis, Animal
      • Horse Diseases / drug therapy
      • Horses / parasitology
      • Parasite Egg Count
      • Perissodactyla / parasitology

      Citations

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