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Home / Equine Research Bank / Vet Rec / Anthelmintic resistant nematodes in Brazilian horses.
The Veterinary record2008; 162(12); 384-385; doi: 10.1136/vr.162.12.384

Anthelmintic resistant nematodes in Brazilian horses.

Abstract: No abstract available
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Publication Date: 2008-03-25 PubMed ID: 18359933DOI: 10.1136/vr.162.12.384Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research paper is about a study conducted in Brazil to analyze the growing issue of resistance in nematodes prevalent in horses. The study investigated the effectiveness of commercial anthelmintics and found increasing resistance to these treatments.

Research Overview

  • The researchers expressed concern over the growing resistance of nematodes, a type of parasitic worm, to anthelmintic treatments in horses.
  • These worms are increasingly becoming resistant to common anthelmintic treatments, including macrocyclic lactones (MLs), pyrantel, and benzimidazoles.
  • Resistance to these treatments is becoming a significant issue for equine welfare and could lead to dire consequences, including death, if left untreated properly.
  • The researchers decided to carry an experiment to understand the effectiveness of these treatments on nematodes present in Brazilian horses.

Experiment Methodolody

  • Groups of six naturally infected horses were treated with commercially available anthelmintic products at the manufacturer’s recommended dosage. The horses used in the study had a fecal egg count greater than 200 eggs per gram of faeces.
  • Fecal samples from the horses were collected at regular intervals (on days 0, 7, 14, 21, and 28), and egg counts were performed following established procedures.

Research Findings

  • The results provided evidence showing increased resistance in nematodes to these anthelmintic treatments.
  • None of the macrocyclic lactones tested were able to adequately control the population of the nematodes.
  • Fenbendazole was effective against one species of the worm, while a combination of ivermectin and pyrantel showed over a 95% reduction in egg counts.
  • The resistance of P. equorum to the MLs was expected, while the resistance to MLs in S. equinus was unexpected.

Consequences and Recommendations

  • If current trends in anthelmintic resistance continue, there will be serious implications for equine welfare globally.
  • To limit the spread of anthelmintic-resistant nematodes, the researchers recommend a combination of tactics including only treating horses with high egg counts, routine assessment of anthelmintic resistance, quarantine and testing of new arrivals, and using non-chemical methods of control such as removing feces from pastures and grazing with sheep or cattle to reduce nematode larvae.

Cite This Article

APA
Molento MB, Antunes J, Bentes RN, Coles GC. (2008). Anthelmintic resistant nematodes in Brazilian horses. Vet Rec, 162(12), 384-385. https://doi.org/10.1136/vr.162.12.384

Publication

The Veterinary record
ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 162
Issue: 12
Pages: 384-385

Researcher Affiliations

Molento, M B
  • Laboratório de Doenças Parasitárias, Universidade Federal do Paraná, Rua dos Funcionários, 1540 Curitiba, PR 80035-050, Brazil.
Antunes, J
    Bentes, R N
      Coles, G C

        MeSH Terms

        • Animals
        • Antinematodal Agents / therapeutic use
        • Brazil
        • Dose-Response Relationship, Drug
        • Drug Resistance
        • Feces / parasitology
        • Female
        • Horse Diseases / drug therapy
        • Horse Diseases / parasitology
        • Horses
        • Male
        • Nematoda / drug effects
        • Nematoda / growth & development
        • Nematode Infections / drug therapy
        • Nematode Infections / parasitology
        • Nematode Infections / veterinary
        • Parasite Egg Count / veterinary
        • Parasitic Sensitivity Tests / veterinary
        • Treatment Outcome

        Citations

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