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Home / Equine Research Bank / J Vet Med Sci / Antibody responses after vaccination against equine influenz...
The Journal of veterinary medical science2015; 77(11); 1517-1521; doi: 10.1292/jvms.15-0192

Antibody responses after vaccination against equine influenza in the Republic of Korea in 2013.

Abstract: In this study, antibody responses after equine influenza vaccination were investigated among 1,098 horses in Korea using the hemagglutination inhibition (HI) assay. The equine influenza viruses, A/equine/South Africa/4/03 (H3N8) and A/equine/Wildeshausen/1/08 (H3N8), were used as antigens in the HI assay. The mean seropositive rates were 91.7% (geometric mean antibody levels (GMT), 56.8) and 93.6% (GMT, 105.2) for A/equine/South Africa/4/03 and A/equine/Wildeshausen/1/08, respectively. Yearlings and two-year-olds in training exhibited lower positive rates (68.1% (GMT, 14) and 61.7% (GMT, 11.9), respectively, with different antigens) than average. Horses two years old or younger may require more attention in vaccination against equine influenza according to the vaccination regime, because they could be a target of the equine influenza virus.
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Publication Date: 2015-06-09 PubMed ID: 26062436PubMed Central: PMC4667675DOI: 10.1292/jvms.15-0192Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article investigates the efficacy of vaccinations against equine influenza in horses in Korea, and found lower than average positive rates in yearlings and two-year-olds in training.

Introduction and Methodology

  • The paper is focused on examining the antibody responses in horses against equine influenza vaccination in Korea. Equine influenza is a highly contagious respiratory disease in horses.
  • The researchers utilized the Hemagglutination Inhibition (HI) assay to measure the level of antibodies in 1,098 horses. The HI assay is a technique used for the serological detection and measurement of antibodies against viruses.
  • Two different types equine influenza viruses, A/equine/South Africa/4/03 (H3N8) and A/equine/Wildeshausen/1/08 (H3N8), were used as antigens in the assay.

Results

  • The study found that the mean seropositive rates among all horses were 91.7% for the A/equine/South Africa/4/03 virus and 93.6% for the A/equine/Wildeshausen/1/08 virus.
  • The Geometric Mean Titre (GMT) was used to express the average antibody level among seropositive horses. The GMT was 56.8 for the A/equine/South Africa/4/03 virus and 105.2 for the A/equine/Wildeshausen/1/08 virus.
  • The results showed that yearlings (young horses between 1 and 2 years old) and two-year-old horses in training exhibited lower positive rates. The rates were 68.1% (GMT, 14) and 61.7% (GMT, 11.9) respectively, with different antigens.

Conclusion

  • The conclusion indicates that horses two years old or younger may require additional attention in the vaccination regime against equine influenza.
  • This is because they could be a potential target of the equine influenza virus owing to their lower positive rates of antibodies in their system, suggesting lesser immunity against the disease.
  • This study contributes to the understanding of equine influenza vaccination efficacy and provides insights on age-sensitive vaccination strategies in horses.

Cite This Article

APA
Kim EJ, Kim BH, Yang S, Choi EJ, Shin YJ, Song JY, Shin YK. (2015). Antibody responses after vaccination against equine influenza in the Republic of Korea in 2013. J Vet Med Sci, 77(11), 1517-1521. https://doi.org/10.1292/jvms.15-0192

Publication

The Journal of veterinary medical science
ISSN: 1347-7439
NlmUniqueID: 9105360
Country: Japan
Language: English
Volume: 77
Issue: 11
Pages: 1517-1521

Researcher Affiliations

Kim, Eun-Ju
  • Viral Disease Division, Animal and Plant Quarantine Agency, Anyang 430-757, Republic of Korea.
Kim, Bo-Hye
    Yang, Sunjoo
      Choi, Eun-Jin
        Shin, Ye-Jin
          Song, Jae-Young
            Shin, Yeun-Kyung

              MeSH Terms

              • Aging
              • Animals
              • Antibodies, Viral / blood
              • Chickens
              • Erythrocytes
              • Female
              • Horse Diseases / blood
              • Horse Diseases / prevention & control
              • Horses
              • Influenza A Virus, H3N8 Subtype / immunology
              • Influenza Vaccines / immunology
              • Male
              • Orthomyxoviridae Infections / blood
              • Orthomyxoviridae Infections / epidemiology
              • Orthomyxoviridae Infections / prevention & control
              • Orthomyxoviridae Infections / veterinary
              • Republic of Korea / epidemiology
              • Vaccination

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              Citations

              This article has been cited 1 times.
              1. Lim SI, Kim MJ, Kim MJ, Lee SK, Yang HS, Kwon M, Lim EH, Ouh IO, Kim EJ, Hyun BH, Lee YH. Assessment of Equine Influenza Virus Status in the Republic of Korea from 2020 to 2022. Viruses 2023 Oct 23;15(10).
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