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Australian veterinary journal2018; 96(8); 297-301; doi: 10.1111/avj.12720

Antifungal non-invasive soak under general anaesthetic to treat fungal rhinitis in an Australian Quarter Horse gelding at pasture.

Abstract: Mycotic rhinitis is a rare disease in horses, with few cases reported worldwide and none reported in Australia. Fungal infection of the upper respiratory tract can occur in all species, but its prevalence in horses is considerably lower than in canines or humans. The disease is linked to a variety of pathogens and the clinical signs are associated with subsequent upper respiratory tract damage. Methods: A 6-year-old Quarter Horse gelding in Queensland, Australia, was presented with chronic nasal discharge and dyspnoea following previous unsuccessful medical treatment of 9 months' duration. Culture yielded a mixed growth of Cryptococcus and Rhodotorula, as well as secondary bacterial species. The horse was anaesthetised and positioned in sternal recumbency. The nasal passages and sinuses were bathed with fluconazole and dimethylsulfoxide for 1 h on two separate occasions 4 weeks apart. Systemic antimicrobials and corticosteroids were also administered for brief courses. Endoscopic examination 4 months after treatment demonstrated clinical resolution of the rhinitis with residual scar tissue. Owners reported resolution of clinical signs and following the treatment the gelding was able to perform athletically. Conclusions: Mycotic rhinitis is an unusual disease that can be difficult to treat successfully. This report describes a technique for topical sinonasal bathing under general anaesthetic that was well tolerated, easy to perform and resulted in a successful clinical outcome.
Publication Date: 2018-08-22 PubMed ID: 30129035DOI: 10.1111/avj.12720Google Scholar: Lookup
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  • Case Reports

Summary

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The research deals with a rare case of fungal infection in the upper respiratory tract of a horse which was treated successfully with a unique method of bathing the nasal and sinus areas while the horse was under general anaesthetic. The horse recovered fully after the treatment, with for the first time such a method was reported in Australia.

Introduction

The article initiates a discussion on Mycotic rhinitis, a rare infectious disease occurring in horses across the globe. Even rarer are the incidents reported in Australia. The infection which inflicts damage to the upper respiratory tract can occur in all species, with a lower prevalence in horses compared to dogs or humans. The disease is found to be related to various pathogens and the clinical indications directly correlate with the consequent damage in the upper respiratory tract.

Methods and Case Overview

  • The case being documented is that of a 6-year-old Quarter Horse gelding in Queensland, Australia, which presented symptoms of chronic nasal discharge and dyspnoea. The horse had been unsuccessfully treated medically for the same over a duration of 9 months.
  • Results from the horse’s culture depicted a mix growth of Cryptococcus and Rhodotorula apart from secondary bacterial species.
  • In the treatment procedure, the horse was anaesthetised and placed in a chest-laying (sternal recumbency) position. The nasal passages and sinuses were immersed with fluconazole and dimethylsulfoxide for an hour, twice, across an interval of 4 weeks.
  • The horsed also received brief courses of systemic antimicrobials and corticosteroids.

Results and Conclusion

  • An endoscopic examination conducted 4 months post the treatment demonstrated clinical resolution of the rhinitis with remaining scar tissue.
  • The owners reported that the horse showed signs of recovery after the treatment and was able to perform athletically.
  • The abstract ends by highlighting the fact that Mycotic rhinitis, being an unusual disease can be tough to treat. However, the report showcases a technique for topical bathing of the nose and sinus under general anaesthetic that was not only well tolerated and easy to execute, but also resulted in a successful clinical outcome.

Cite This Article

APA
Lean NE, Ahern BJ. (2018). Antifungal non-invasive soak under general anaesthetic to treat fungal rhinitis in an Australian Quarter Horse gelding at pasture. Aust Vet J, 96(8), 297-301. https://doi.org/10.1111/avj.12720

Publication

ISSN: 1751-0813
NlmUniqueID: 0370616
Country: England
Language: English
Volume: 96
Issue: 8
Pages: 297-301

Researcher Affiliations

Lean, N E
  • University of Queensland Equine Specialist Hospital, Outer Ring Road, Gatton, Queensland 4343, Australia.
Ahern, B J
  • University of Queensland Equine Specialist Hospital, Outer Ring Road, Gatton, Queensland 4343, Australia.

MeSH Terms

  • Anesthesia, General / veterinary
  • Animals
  • Antifungal Agents / administration & dosage
  • Cryptococcus / isolation & purification
  • Endoscopy / veterinary
  • Horse Diseases / drug therapy
  • Horse Diseases / microbiology
  • Horses
  • Male
  • Mycoses / drug therapy
  • Mycoses / veterinary
  • Queensland
  • Rhinitis / drug therapy
  • Rhinitis / microbiology
  • Rhinitis / veterinary
  • Rhodotorula / isolation & purification
  • Treatment Outcome

Citations

This article has been cited 1 times.
  1. Hardefeldt L, Thomas K, Page S, Norris J, Browning G, El Hage C, Stewart A, Gilkerson J, Muscatello G, Verwilghen D, van Galen G, Bauquier J, Cuming R, Reynolds B, Whittaker C, Wilkes E, Clulow J, Burden C, Begg L. Antimicrobial prescribing guidelines for horses in Australia. Aust Vet J 2025 Dec;103(12):781-889.
    doi: 10.1111/avj.70003pubmed: 40903020google scholar: lookup