Association between exercise-induced pulmonary hemorrhage and performance in Thoroughbred racehorses.
Abstract: To determine whether exercise-induced pulmonary hemorrhage (EIPH) was associated with racing performance inThoroughbred horses not medicated with furosemide and not using nasal dilator strips. Methods: Observational cross-sectional study. Methods: 744 two- to 10-year-old Thoroughbred horses racing in Melbourne, Australia. Methods: Horses were enrolled prior to racing, and a tracheobronchoscopic examination was performed after 1 race. Examinations were recorded on videotape, and presence and severity (grade 0 to 4) of EIPH were subsequently determined by 3 observers blinded to the horses' identity. Race records were abstracted for each horse examined. Results: Overall, 52.1% of horses eligible for participation in the study were examined, and horses that were examined did not differ from horses that were not examined in regard to age, sex distribution, or proportion of horses that won or finished in the first 3 positions. Horses with EIPH grades < 1 were 4.0 times as likely to win, 1.8 times as likely to finish in the first 3 positions, and 3.03 times as likely to be in the 90th percentile or higher for race earnings as were horses with grades > 2. Horses with EIPH grades > 1 finished significantly farther behind the winner than did horses without EIPH. However, odds that horses with grade 1 EIPH would win or finish in the first 3 positions were not significantly different from odds for horses without EIPH. Conclusions: Results suggest that EIPH is associated with impaired performance in Thoroughbred racehorses not medicated with furosemide and not using nasal dilator strips.
Publication Date: 2005-09-24 PubMed ID: 16178399DOI: 10.2460/javma.2005.227.768Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The research investigates the association between exercise-induced pulmonary hemorrhage (EIPH) and racing performance in Thoroughbred horses. The study finds that EIPH can negatively affect a horse’s performance, especially without the use of medication or specialized nasal dilator strips.
Research Methodology
- The research was an observational cross-sectional study focused on Thoroughbred horses aged between two and ten years, competing in Melbourne, Australia.
- A total of 744 horses were included in the study, each inspected before and after a race using a tracheobronchoscopic examination. This medical procedure evaluates the airways (bronchi) and the voice box (larynx).
- The examinations were videotaped, and the existence and severity of EIPH (graded between 0 and 4) were identified by three observers who were not given information about the horses’ identities.
- Horse racing records were also examined for each horse included in the study.
Findings
- About 52.1% of the horses eligible for the study were examined. The demographics (age, sex) and racing performance (winning ratio, top-3 finish ratio) of the examined horses did not differ significantly from the non-examined ones.
- Horses with minor EIPH (grading less than 1) were far more likely to win a race, finish in top-3, or earn higher race winnings (within the top 10% of earners) compared to those with severe EIPH (grading above 2).
- Horses with EIPH grade of more than 1, finished significantly behind the winner compared to horses without EIPH.
- However, the chances of horses with EIPH grade 1 winning or finishing in the top three were not significantly different from those horses without EIPH.
Conclusion
- The study justifies the association of EIPH with impaired racing performance in Thoroughbred horses, particularly those not medicated with furosemide or those not using nasal dilator strips to ease breathing.
Cite This Article
APA
Hinchcliff KW, Jackson MA, Morley PS, Brown JA, Dredge AE, O'Callaghan PA, McCaffrey JP, Slocombe RE, Clarke AE.
(2005).
Association between exercise-induced pulmonary hemorrhage and performance in Thoroughbred racehorses.
J Am Vet Med Assoc, 227(5), 768-774.
https://doi.org/10.2460/javma.2005.227.768 Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USA.
MeSH Terms
- Animals
- Bronchoscopy / veterinary
- Cross-Sectional Studies
- Female
- Hemorrhage / physiopathology
- Hemorrhage / veterinary
- Horse Diseases / physiopathology
- Horses
- Lung Diseases / physiopathology
- Lung Diseases / veterinary
- Male
- Physical Conditioning, Animal / physiology
- Severity of Illness Index
- Videotape Recording
Citations
This article has been cited 15 times.- Lo Feudo CM, Stucchi L, Stancari G, Conturba B, Bozzola C, Zucca E, Ferrucci F. Associations between Medical Disorders and Racing Outcomes in Poorly Performing Standardbred Trotter Racehorses: A Retrospective Study. Animals (Basel) 2023 Aug 9;13(16).
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- Cullinane A, Garvey M, Walsh C, Gibbons J, Creighton A. A Scoping Review of Non-Structural Airway Disease as a Cause of Poor Performance in Racehorses. Animals (Basel) 2023 Jan 27;13(3).
- Bertram CA, Marzahl C, Bartel A, Stayt J, Bonsembiante F, Beeler-Marfisi J, Barton AK, Brocca G, Gelain ME, Gläsel A, Preez KD, Weiler K, Weissenbacher-Lang C, Breininger K, Aubreville M, Maier A, Klopfleisch R, Hill J. Cytologic scoring of equine exercise-induced pulmonary hemorrhage: Performance of human experts and a deep learning-based algorithm. Vet Pathol 2023 Jan;60(1):75-85.
- Marzahl C, Hill J, Stayt J, Bienzle D, Welker L, Wilm F, Voigt J, Aubreville M, Maier A, Klopfleisch R, Breininger K, Bertram CA. Inter-species cell detection - datasets on pulmonary hemosiderophages in equine, human and feline specimens. Sci Data 2022 Jun 3;9(1):269.
- Lo Feudo CM, Stucchi L, Stancari G, Alberti E, Conturba B, Zucca E, Ferrucci F. Associations between Exercise-Induced Pulmonary Hemorrhage (EIPH) and Fitness Parameters Measured by Incremental Treadmill Test in Standardbred Racehorses. Animals (Basel) 2022 Feb 12;12(4).
- Lopez Sanchez CM, Kogan C, Gold JR, Sellon DC, Bayly WM. Relationship between tracheobronchoscopic score and bronchoalveolar lavage red blood cell numbers in the diagnosis of exercise-induced pulmonary hemorrhage in horses. J Vet Intern Med 2020 Jan;34(1):322-329.
- Poole DC, Erickson HH. Exercise-induced pulmonary hemorrhage: where are we now?. Vet Med (Auckl) 2016;7:133-148.
- Léguillette R, Steinmann M, Bond SL, Stanton B. Tracheobronchoscopic Assessment of Exercise-Induced Pulmonary Hemorrhage and Airway Inflammation in Barrel Racing Horses. J Vet Intern Med 2016 Jul;30(4):1327-32.
- Hinchcliff KW, Couetil LL, Knight PK, Morley PS, Robinson NE, Sweeney CR, van Erck E. Exercise induced pulmonary hemorrhage in horses: American College of Veterinary Internal Medicine consensus statement. J Vet Intern Med 2015 May-Jun;29(3):743-58.
- Diwakar A, Schmidt GA. Exercise-induced pulmonary hemorrhage in a nonathlete: case report and review of physiology. Lung 2014 Apr;192(2):329-31.
- Perez-Moreno CI, Couëtil LL, Pratt SM, Ochoa-Acuña HG, Raskin RE, Russell MA. Effect of furosemide and furosemide-carbazochrome combination on exercise-induced pulmonary hemorrhage in Standardbred racehorses. Can Vet J 2009 Aug;50(8):821-7.
- Shoemaker S, Wang Y, Sellon D, Gold J, Fisher A, Bagshaw J, Leguillette R, Sanz M, Bayly W. Prevalence and severity of exercise-induced pulmonary hemorrhage in 2-year-old Thoroughbred racehorses and its relationship to performance. J Vet Intern Med 2024 Mar-Apr;38(2):1167-1176.
- Nath LC, Elliott A, La Gerche A, Weir J, Forbes G, Thomas G, Franklin S. Associations between postrace atrial fibrillation and measures of performance, racing history and airway disease in horses. J Vet Intern Med 2023 Nov-Dec;37(6):2573-2583.
- Marzahl C, Aubreville M, Bertram CA, Stayt J, Jasensky AK, Bartenschlager F, Fragoso-Garcia M, Barton AK, Elsemann S, Jabari S, Krauth J, Madhu P, Voigt J, Hill J, Klopfleisch R, Maier A. Deep Learning-Based Quantification of Pulmonary Hemosiderophages in Cytology Slides. Sci Rep 2020 Aug 3;10(1):9795.
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