FREE SHIPPING over $40
OVER 10000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire1989; 53(2); 202-209;

Attempts to restore abduction of the paralyzed equine arytenoid cartilage. I. Nerve-muscle pedicle transplants.

Abstract: The purpose of this project was to adapt a surgical technique from humans and dogs to horses in which a portion of an accessory muscle of respiration and its nerve supply is transplanted to a denervated dorsal cricoarytenoid muscle. Anatomical dissections in seven horses revealed two possible donor nerve-pedicle grafts: the omohyoid and the sternothyrohyoid, both innervated by a branch of the first and second cervical nerves. Histochemical evaluations in two ponies of the dorsal cricoarytenoid, omohyoid and sternothyrohyoid muscles revealed similar proportions of fiber types 1 and 2 in all three muscles. Electromyographic studies in these two ponies revealed that the omohyoid and sternothyrohyoid muscles contract synchronously with respirations during forced inspiration under general anesthesia. Based on surgical ease of access, a 1 cm2 portion of the omohyoid muscle at the point of penetration of the second cervical nerve was used as a nerve-muscle pedicle graft in an attempt to reinnervate the left dorsal cricoarytenoid muscle in four ponies. These four ponies (as well as three others which served as controls) had previously undergone left recurrent laryngeal nerve transection. All seven ponies endoscopically showed signs of complete left laryngeal hemiplegia immediately postoperatively. Animals were monitored endoscopically for 30 weeks after surgery. The three control ponies showed no abduction of the arytenoid cartilage. In addition, in these three ponies, histological and histochemical expected changes of muscle fiber atrophy and fibrosis were present in the dorsal cricoarytenoid muscle.(ABSTRACT TRUNCATED AT 250 WORDS)
Get Full Text
Publication Date: 1989-04-01 PubMed ID: 2713785PubMed Central: PMC1255548
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates the use of nerve-muscle pedicle transplants in horses to restore the function of respiratory-associated muscles that control an anatomical structure found in their throat called the arytenoid cartilage. This technique, which has been previously applied in humans and dogs, involves moving a nerve and its associated muscle from one location to another to reactivate a muscle that has lost its original nerve supply.

Surgical technique adaptation

The research aimed to adapt a surgical technique usually performed on humans and dogs for use on horses. The procedure involves transplanting a part of a muscle (in this case, a respiratory muscle) and its nerve supply to a muscle that has lost its nerve supply due to paralysis. This process could potentially restore motion and function to the affected muscle.

Anatomical dissections

  • Seven horses underwent anatomical dissections, which revealed two possible donor nerve-pedicle grafts: the omohyoid and sternothyrohyoid muscle. Both of these muscles are controlled by the first and second cervical nerves.

Histochemical evaluations

  • The research also includes histochemical evaluations of the targeted muscles in two ponies, showing similar types of muscle fibers in the three muscles: the dorsal cricoarytenoid, omohyoid and sternothyrohyoid.

Electromyographic studies

  • Electromyographic (muscle function) studies showed that the muscles chosen for the donor grafts contracted in sync with the horse’s breathing during forced inspiration under general anesthesia.

Surgical application and follow-up

  • The technique was then applied in four ponies, using a section of the omohyoid muscle and its second cervical nerve to reinnervate the left dorsal cricoarytenoid muscle, a muscle that controls the arytenoid cartilage in the horse’s airway.
  • Post-surgery observations for 30 weeks provided evidence for the effectiveness of the procedure. Although the control group of ponies showed no movement in their arytenoid cartilage and signs of muscle atrophy, the article abstract ends before the results of the treated group are stated.

Cite This Article

APA
Ducharme NG, Horney FD, Partlow GD, Hulland TJ. (1989). Attempts to restore abduction of the paralyzed equine arytenoid cartilage. I. Nerve-muscle pedicle transplants. Can J Vet Res, 53(2), 202-209.

Publication

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
ISSN: 0830-9000
NlmUniqueID: 8607793
Country: Canada
Language: English
Volume: 53
Issue: 2
Pages: 202-209

Researcher Affiliations

Ducharme, N G
  • Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph.
Horney, F D
    Partlow, G D
      Hulland, T J

        MeSH Terms

        • Animals
        • Arytenoid Cartilage / physiopathology
        • Electromyography / veterinary
        • Horse Diseases / surgery
        • Horses
        • Laryngeal Cartilages / physiopathology
        • Laryngeal Muscles / innervation
        • Laryngeal Muscles / physiopathology
        • Muscle Contraction
        • Muscle Denervation
        • Muscles / innervation
        • Respiratory Muscles / innervation
        • Respiratory Muscles / physiopathology
        • Surgical Flaps / veterinary
        • Vocal Cord Paralysis / surgery
        • Vocal Cord Paralysis / veterinary

        References

        This article includes 23 references
        1. Med Sci Sports Exerc. 1983;15(3):187-98
          pubmed: 6353126
        2. Laryngoscope. 1976 Jun;86(6):769-79
          pubmed: 933669
        3. Acta Otolaryngol. 1974 Jul-Aug;78(1-2):124-8
          pubmed: 4413488
        4. Ann Otol Rhinol Laryngol. 1987 Mar-Apr;96(2 Pt 1):152-7
          pubmed: 3551740
        5. J Anat. 1944 Jan;78(Pt 1-2):15-43
          pubmed: 17104938
        6. Equine Vet J. 1979 Jul;11(3):153-8
          pubmed: 488064
        7. N Z Vet J. 1982 Jan-Feb;30(1-2):1-5
          pubmed: 16030817
        8. Otolaryngol Head Neck Surg. 1982 Jul-Aug;90(4):442-7
          pubmed: 6817274
        9. Laryngoscope. 1956 Apr;66(4):410-25
          pubmed: 13320954
        10. Arch Otolaryngol. 1970 Dec;92(6):530-3
          pubmed: 5486949
        11. Equine Vet J. 1973 Apr;5(2):77-80
          pubmed: 4275248
        12. Acta Otolaryngol. 1970 Sep;70(3):203-11
          pubmed: 4920459
        13. Arch Otolaryngol. 1974 Sep;100(3):176-9
          pubmed: 4851285
        14. Arch Otolaryngol. 1973 Mar;97(3):247-50
          pubmed: 4696035
        15. Laryngoscope. 1968 Feb;78(2):236-50
          pubmed: 4868192
        16. Equine Vet J. 1987 Sep;19(5):377-83
          pubmed: 3315646
        17. Equine Vet J. 1972 Jul;4(3):144-8
          pubmed: 4265667
        18. Laryngoscope. 1982 Sep;92(9 Pt 2 Suppl 30):1-27
          pubmed: 7109807
        19. Laryngoscope. 1985 Apr;95(4):455-7
          pubmed: 3982186
        20. Acta Neuropathol. 1974 Apr 30;27(4):337-48
          pubmed: 4407536
        21. Laryngoscope. 1971 Oct;81(10):1602-6
          pubmed: 5114160
        22. Ann Otol Rhinol Laryngol. 1982 Jul-Aug;91(4 Pt 1):440-4
          pubmed: 7114728
        23. Am J Vet Res. 1986 Jan;47(1):16-20
          pubmed: 3946898

        Citations

        This article has been cited 3 times.
        1. Greenfield CL, Alsup JC, Hungerford LL, McKiernan BC. Bilateral recurrent laryngeal neurectomy as a model for the study of idiopathic canine laryngeal paralysis. Can Vet J 1997 Mar;38(3):163-7.
          pubmed: 9056067
        2. Ducharme NG, Viel L, Partlow GD, Hulland TJ, Horney FD. Attempts to restore abduction of the paralyzed equine arytenoid cartilage. III. Nerve anastomosis. Can J Vet Res 1989 Apr;53(2):216-23.
          pubmed: 2713787
        3. Ducharme NG, Horney FD, Hulland TJ, Partlow GD, Schnurr D, Zutrauen K. Attempts to restore abduction of the paralyzed equine arytenoid cartilage. II. Nerve implantation (pilot study). Can J Vet Res 1989 Apr;53(2):210-5.
          pubmed: 2713786
        Subscribe to our newsletter
        Join 99,727 horse owners like you who receive our email updates on horse health and nutrition.