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The Veterinary record2023; 192(9); e2732; doi: 10.1002/vetr.2732

Benefits of cyanoacrylate mesh closure following exploratory laparotomy in horses.

Abstract: Skin closure of laparotomy incisions using topical 2-octyl cyanoacrylate (2-OCA) mesh provides a secure bactericidal barrier in humans, which may reduce the risk of postoperative incisional complications. However, the benefits of using this mesh have not been objectively assessed in horses. Methods: From 2009 to 2020, three methods of skin closure were used following laparotomy for acute colic, including metallic staples (MS), suture (ST) and cyanoacrylate mesh (DP). The closure method was not randomised. Owners were contacted 3 months or more after the surgery to record any postoperative complications that occurred. For each method of closure, the rates of surgical site infection (SSI) and herniation were recorded, as well as surgical time and treatment costs, including those for incisional complications. Chi-square testing and logistic regression modelling were used to assess differences between the groups. Results: A total of 110 horses were recruited (45 in the DP group, 49 in the MS group and 16 in the ST group) The overall rate of SSI was 15.5%, with rates of 8.9%, 18.4% and 25% for the DP, MS and ST groups, respectively (p = 0.23). In addition, incisional hernias developed in 21.8% of cases, with 8.9%, 34.7% and 18.8% of horses in the DP, MS and ST groups, respectively, being affected (p = 0.009). The median total treatment cost did not differ significantly between groups (p = 0.47). Conclusions: This was a retrospective study with non-randomised choice of closure method. Conclusions: No significant differences in the rate of SSI or overall cost wwere demonstrated between treatment groups. However, MS was associated with a higher rate of hernia formation than DP or ST. Despite increased capital cost, 2-OCA proved to be a safe skin closure method in horses and was no more expensive than DP or ST by the time visits to remove sutures/staples and treat infections were factored in.
© 2023 British Veterinary Association.
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Publication Date: 2023-02-21 PubMed ID: 36809672DOI: 10.1002/vetr.2732Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates the use of a topical adhesive mesh for closing incisions after surgery in horses, suggesting it’s a safe, cost-effective method compared to traditional sutures or staples, notably with a lesser association with hernia formation despite higher initial cost.

Methods Used

  • The study was conducted over a span of 11 years (2009-2020).
  • Three methods of skin closure were utilized after horse laparotomy surgery: metallic staples (MS), suture (ST), and a cyanoacrylate adhesive mesh (DP).
  • Choice of closure method was not randomized.
  • Owners of the horses were followed up with three or more months after surgery to document postoperative complications.
  • The rates of surgical site infection (SSI) and herniation (bulging of an organ or tissue through an abnormal opening), surgical time, and treatment costs were tracked for each closure method.
  • Data was analyzed using chi-square testing and logistic regression modelling.

Research Findings

  • A total of 110 horses were recruited for the study with varying numbers in each group (45 in the DP group, 49 in the MS group, and 16 in the ST group).
  • The overall rate of SSI across all groups was 15.5% – with lower rate in DP group (8.9%) than MS (18.4%) and ST (25%) groups.
  • Incisional hernias were found in 21.8% of total cases. Again, the DP group (8.9%) had lower rates than the MS (34.7%) and ST (18.8%) groups.
  • There was no significant difference in total treatment costs between the three groups.

Study Conclusion

  • Despite being a retrospective study with non-randomized selection of closure method, the research provides valuable insights.
  • No significant difference was found in the rate of SSI incidents or overall treatment cost among the three groups.
  • However, the use of metallic staples (MS) was linked to a higher rate of hernia formation than either DP or ST.
  • Although 2-octyl cyanoacrylate (2-OCA) adhesive mesh has a higher initial cost, it’s proven to be a safe, eventually cost-effective skin closure method in horses, particularly when the costs associated with follow-up visits to remove sutures or staples and treating infections are factored in.

Cite This Article

APA
Terschuur JA, Coomer RPC, Handel I, Pressanto MC, McKane SA. (2023). Benefits of cyanoacrylate mesh closure following exploratory laparotomy in horses. Vet Rec, 192(9), e2732. https://doi.org/10.1002/vetr.2732

Publication

The Veterinary record
ISSN: 2042-7670
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 192
Issue: 9
Pages: e2732

Researcher Affiliations

Terschuur, Janine Astrid
  • Cotts Equine Hospital, Robeston Wathen, Narberth, Wales, UK.
Coomer, Richard P C
  • Cotts Equine Hospital, Robeston Wathen, Narberth, Wales, UK.
Handel, Ian
  • The Royal (Dick) School of Veterinary Studies and The Roslin Institute, Roslin, Midlothian, UK.
Pressanto, Maria Chiara
  • Cotts Equine Hospital, Robeston Wathen, Narberth, Wales, UK.
McKane, Shaun A
  • Cotts Equine Hospital, Robeston Wathen, Narberth, Wales, UK.

MeSH Terms

  • Humans
  • Horses
  • Animals
  • Laparotomy / adverse effects
  • Laparotomy / veterinary
  • Retrospective Studies
  • Surgical Mesh / veterinary
  • Surgical Mesh / adverse effects
  • Surgical Wound Infection / epidemiology
  • Surgical Wound Infection / prevention & control
  • Surgical Wound Infection / veterinary
  • Cyanoacrylates / therapeutic use
  • Horse Diseases / surgery

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