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Home / Equine Research Bank / Can Vet J / Bilateral diffuse cystic renal dysplasia in a 9-day-old Thor...
The Canadian veterinary journal = La revue veterinaire canadienne2014; 55(2); 141-146;

Bilateral diffuse cystic renal dysplasia in a 9-day-old Thoroughbred filly.

Abstract: A 9-day-old Thoroughbred filly was presented for diarrhea and lethargy. Diagnostic test results were compatible with severe renal dysfunction. Diffuse cystic lesions of both kidneys were identified on ultrasonographic examination. Postmortem examination confirmed the presence of multiple renal cysts. Congenital nephropathy compatible with bilateral diffuse cystic renal dysplasia was diagnosed. Une pouliche Thoroughbred âgée de 9 jours a été présentée pour de la diarrhée et de la léthargie. Les résultats des tests diagnostiques étaient compatibles avec une dysfonction rénale grave. Des lésions kystiques diffuses des deux reins ont été identifiées à l’échographie. L’examen postmortem a confirmé la présence de kystes rénaux multiples. Une néphropathie congénitale compatible avec la dysplasie rénale kystique diffuse bilatérale a été diagnostiquée.(Traduit par Isabelle Vallières).
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Publication Date: 2014-02-04 PubMed ID: 24489392PubMed Central: PMC3894871
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research describes a case of a nine-day-old Thoroughbred filly who was diagnosed with a severe renal disorder, specifically bilateral diffuse cystic renal dysplasia, after presenting symptoms of lethargy and diarrhea.

Case Presentation and Initial Assessment

  • A Thoroughbred filly, only nine days old, was brought in due to symptoms of diarrhea and lethargy. These clinical signs raised immediate concerns about a serious health problem that warranted thorough diagnostic examination.

Diagnostic Process

  • To determine the cause of the filly’s symptoms, several diagnostic tests were conducted. These tests revealed that the filly was suffering from severe kidney dysfunction, indicated by the abnormal parameters in the tests.
  • An ultrasonographic examination was carried out to further explore the condition of the kidneys. This imaging procedure unveiled the presence of diffuse cystic lesions in both kidneys. Having cystic lesions scattered throughout the kidney tissue is a worrying sign of potential serious kidney disease.

Postmortem Examination and Final Diagnosis

  • Following the filly’s death, a postmortem examination was conducted which confirmed the presence of numerous cysts in the kidneys. Multiple renal cysts are abnormal pouches containing fluid that occur within the kidneys and severely impact kidney function.
  • Based on the identified health abnormalities and pathological manifestations, a final diagnosis of congenital nephropathy compatible with bilateral diffuse cystic renal dysplasia was made. This is a rare, severe kidney disorder that is present from birth and is characterized by the development of widespread cysts in both kidneys resulting in severe kidney dysfunction.

Cite This Article

APA
Medina-Torres CE, Hewson J, Stämpfli S, Stalker MJ. (2014). Bilateral diffuse cystic renal dysplasia in a 9-day-old Thoroughbred filly. Can Vet J, 55(2), 141-146.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 55
Issue: 2
Pages: 141-146

Researcher Affiliations

Medina-Torres, Carlos E
  • Department of Clinical Studies (Medina-Torres, Hewson) and Veterinary Teaching Hospital (Stämpfli), Ontario Veterinary College; Animal Health Laboratory (Stalker), University of Guelph, Guelph, Ontario.
Hewson, Joanne
  • Department of Clinical Studies (Medina-Torres, Hewson) and Veterinary Teaching Hospital (Stämpfli), Ontario Veterinary College; Animal Health Laboratory (Stalker), University of Guelph, Guelph, Ontario.
Stämpfli, Simon
  • Department of Clinical Studies (Medina-Torres, Hewson) and Veterinary Teaching Hospital (Stämpfli), Ontario Veterinary College; Animal Health Laboratory (Stalker), University of Guelph, Guelph, Ontario.
Stalker, Margaret J
  • Department of Clinical Studies (Medina-Torres, Hewson) and Veterinary Teaching Hospital (Stämpfli), Ontario Veterinary College; Animal Health Laboratory (Stalker), University of Guelph, Guelph, Ontario.

MeSH Terms

  • Animals
  • Animals, Newborn
  • Female
  • Horse Diseases / pathology
  • Horses
  • Kidney Diseases, Cystic / pathology
  • Kidney Diseases, Cystic / veterinary

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Citations

This article has been cited 3 times.
  1. Sieben CJ, Harris PC. Experimental Models of Polycystic Kidney Disease: Applications and Therapeutic Testing. Kidney360 2023 Aug 1;4(8):1155-1173.
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  2. Sprayberry KA. Ultrasonographic Examination of the Equine Neonate: Thorax and Abdomen. Vet Clin North Am Equine Pract 2015 Dec;31(3):515-43.
    doi: 10.1016/j.cveq.2015.09.004pubmed: 26612746google scholar: lookup
  3. Gu J, Liu F, Li L, Mao J. Advances and Challenges in Modeling Autosomal Dominant Polycystic Kidney Disease: A Focus on Kidney Organoids. Biomedicines 2025 Feb 19;13(2).
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