FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Can Vet J / Bilateral occurrence of granulosa-theca cell tumors in an Ar...
The Canadian veterinary journal = La revue veterinaire canadienne2007; 48(5); 502-505;

Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare.

Abstract: An Arabian mare was referred for right granulosa-theca cell tumor (GTCT) evaluation. The mare was presented 4.5 years later for a left GTCT, after successfully conceiving and delivering a normal foal in the interim. The concurrent or nonconcurrent occurrence of bilateral GTCT in mares appears to be rare. Une jument Arabe a été référée pour l’évaluation d’une tumeur de la granulosa et de la thèque du côté droit (TGT). La jument avait été présentée 4,5 ans plus tôt pour une TGT du côté gauche, ayant entre temps conçu et mis au monde un poulain normal. La présence, simultanée ou non, de TGT bilatérales chez la jument semble être un fait rare. (Traduit par Docteur André Blouin)
Get Full Text
Publication Date: 2007-06-05 PubMed ID: 17542368PubMed Central: PMC1852596
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Case Reports
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study explores an uncommon case where an Arabian mare developed bilateral granulosa-theca cell tumors (GTCT) over a 4.5 year span, but was also able to successfully conceive and deliver a foal during this period.

Context and Aim of the Research

  • This research revolves around the occurrence of granulosa-theca cell tumors (GTCT) in an Arabian mare. GTCTs are tumors that affect the ovarian tissues in horses, often leading to changes in behavior due to altered hormone levels.
  • The study aimed at examining the unique case of an Arabian mare who developed GTCTs on both the right and left side, which appears to be a rare occurrence.

Findings and Outcomes

  • The mare was initially diagnosed with a GTCT on the right side and was later presented after 4.5 years with a GTCT on the left side.
  • Remarkably, in the interim period between the occurrence of the two tumors, the mare was able to successfully conceive and give birth to a healthy foal.
  • The capability of this mare to recreate despite the bilateral occurrence of these tumors suggests that these types of tumors may not necessarily hinder reproduction in horses, or that individual response to such tumors can significantly vary.

Significance of the Research

  • The research underscores the rarity of bilateral GTCTs in mares and provides a unique case study for further exploration and understanding of this disease and its potential impacts on the reproductive abilities of the horse.
  • The findings could be beneficial for equine practitioners in diagnosing and treating similar cases, particularly where distinct diagnosis might result in different treatment methods.

Cite This Article

APA
Frederico LM, Gerard MP, Pinto CR, Gradil CM. (2007). Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare. Can Vet J, 48(5), 502-505.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 48
Issue: 5
Pages: 502-505

Researcher Affiliations

Frederico, Lisa M
  • Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, North Carolina 27606, USA.
Gerard, Mathew P
    Pinto, Carlos R F
      Gradil, Carlos M

        MeSH Terms

        • Aggression
        • Animals
        • Female
        • Granulosa Cell Tumor / blood
        • Granulosa Cell Tumor / diagnosis
        • Granulosa Cell Tumor / surgery
        • Granulosa Cell Tumor / veterinary
        • Horse Diseases / blood
        • Horse Diseases / diagnosis
        • Horses
        • Ovarian Neoplasms / blood
        • Ovarian Neoplasms / diagnosis
        • Ovarian Neoplasms / surgery
        • Ovarian Neoplasms / veterinary
        • Ovariectomy / methods
        • Ovariectomy / veterinary
        • Thecoma / blood
        • Thecoma / diagnosis
        • Thecoma / surgery
        • Thecoma / veterinary
        • Treatment Outcome

        References

        This article includes 20 references
        1. Trotter G, Embertson R. The uterus and ovaries. In: Auer JA, Stick JA, eds. Equine Surgery. 2nd ed. Philadelphia: WB Saunders, 1999:575–583.
        2. Hinrichs K, Cochran SL, Schelling SH, Steckel RR. Granulosa-theca cell tumor associated with an ovulation fossa and normal ovarian stroma in a mare.. J Am Vet Med Assoc 1992 Mar 1;200(5):696-8.
          pubmed: 1314794
        3. Turner TA, Manno M. Bilateral granulosa cell tumor in a mare.. J Am Vet Med Assoc 1983 Apr 1;182(7):713-4.
          pubmed: 6841259
        4. McCoy DJ. Diabetes mellitus associated with bilateral granulosa cell tumors in a mare.. J Am Vet Med Assoc 1986 Apr 1;188(7):733-5.
          pubmed: 3700232
        5. Ragle CA, Southwood LL, Hopper SA, Buote PL. Laparoscopic ovariectomy in two horses with granulosa cell tumors.. J Am Vet Med Assoc 1996 Sep 15;209(6):1121-4.
          pubmed: 8800261
        6. Rodgerson DH, Brown MP, Watt BC, Keoughan CG, Hanrath M. Hand-assisted laparoscopic technique for removal of ovarian tumors in standing mares.. J Am Vet Med Assoc 2002 May 15;220(10):1503-7, 1475.
          pubmed: 12018378doi: 10.2460/javma.2002.220.1503google scholar: lookup
        7. Carson-Dunkerley SA, Hanson RR. Ovariectomy of granulosa cell tumors in mares by use of the diagonal paramedian approach: 12 cases (1989-1995).. J Am Vet Med Assoc 1997 Jul 15;211(2):204-6.
          pubmed: 9227752
        8. Fessler JF, Brobst DF. Granulosa cell tumor.. Cornell Vet 1972 Jan;62(1):110-23.
          pubmed: 5061937
        9. Moll HD, Slone DE, Juzwiak JS, Garrett PD. Diagonal paramedian approach for removal of ovarian tumors in the mare.. Vet Surg 1987 Nov-Dec;16(6):456-8.
          pubmed: 3507181doi: 10.1111/j.1532-950x.1987.tb00987.xgoogle scholar: lookup
        10. Sedrish SA, McClure JR, Pinto C, Oliver J, Burba DJ. Ovarian torsion associated with granulosa-theca cell tumor in a mare.. J Am Vet Med Assoc 1997 Nov 1;211(9):1152-4.
          pubmed: 9364230
        11. Patrick DJ, Kiupel M, Gerber V, Carr EA. Malignant granulosa-theca cell tumor in a two-year-old Miniature Horse.. J Vet Diagn Invest 2003 Jan;15(1):60-3.
          pubmed: 12580299doi: 10.1177/104063870301500114google scholar: lookup
        12. Gift LJ, Gaughan EM, Schoning P. Metastatic granulosa cell tumor in a mare.. J Am Vet Med Assoc 1992 May 15;200(10):1525-6.
          pubmed: 1612993
        13. Rambags BP, Stout TA, Rijkenhuizen AB. Ovarian granulosa cell tumours adherent to other abdominal organs; surgical removal from 2 warmblood mares.. Equine Vet J 2003 Sep;35(6):627-32.
          pubmed: 14515967doi: 10.2746/042516403775467261google scholar: lookup
        14. Chopin JB, Chopin LK, Knott LM, de Kretser DM, Dowsett KF. Unusual ovarian activity in a mare preceding the development of an ovarian granulosa cell tumour.. Aust Vet J 2002 Jan-Feb;80(1-2):32-6.
          pubmed: 12180875
        15. Wilson DA, Foreman JH, Boero MJ, Didier PJ, Lerner DJ. Small-colon rupture attributable to granulosa cell tumor in a mare.. J Am Vet Med Assoc 1989 Mar 1;194(5):681-2.
          pubmed: 2925483
        16. Christman SA, Bailey MT, Wheaton JE, Troedsson MH, Ababneh MM, Santschi EM. Dimeric inhibin concentrations in mares with granulosa-theca cell tumors.. Am J Vet Res 1999 Nov;60(11):1407-10.
          pubmed: 10566817
        17. Bailey MT, Troedsson MH, Wheato JE. Inhibin concentrations in mares with granulosa cell tumors.. Theriogenology 2002 Apr 15;57(7):1885-95.
          pubmed: 12041692doi: 10.1016/s0093-691x(02)00658-1google scholar: lookup
        18. Watson ED. Reproduction. In: Mair T, Love S, Schumacher J, Watson E, eds. Equine Medicine, Surgery and Reproduction. London: WB Saunders, 1998:278–309.
        19. McCue PM. Equine granulosa cell tumors. Proc 38th Annu Conv Am Assoc Equine Pract 1992:587–593.
        20. Clark TL. Clinical management of equine ovarian neoplasms.. J Reprod Fertil Suppl 1975 Oct;(23):331-4.
          pubmed: 1060801

        Citations

        This article has been cited 1 times.
        1. Melgaard DT, Korsgaard TS, Thoefner MS, Petersen MR, Pedersen HG. Moody Mares-Is Ovariectomy a Solution?. Animals (Basel) 2020 Jul 16;10(7).
          doi: 10.3390/ani10071210pubmed: 32708618google scholar: lookup
        Subscribe to our newsletter
        Join 99,359 horse owners like you who receive our email updates on horse health and nutrition.