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[Blood serum level of primary bile acids in cattle, horses, swine and dogs].

Abstract: The levels of the two primary bile acids, cholic acid (CA) and chenodeoxycholic acid (CDCA), were determined by radioimmunoassay in cattle, horse, pig and dog serum. The mean serum cholic acid (SCA) and deoxycholic acid (SCDCA) levels of cows varied with their reproductive status, being 7.8 (+/- 3.3) and 1.5 (+/- 1.0) mumol/l in dry cows, 17.8 (+/- 6.9) and 2.3 (+/- 1.0) mumol/l in freshly calved dams, and 15.8 (+/- 5.7) and 2.3 (+/- 0.8) mumol/l, respectively, in lactating cows. The SCA level found in the immediate prepartal period and also on the day of calving corresponded to those found during the dry period, then, they tended to rise 2 days after calving and attained the peak characteristic for freshly calved dams on day 3 or 4 post partum. Feed consumption had no influence on the serum levels of primary bile acids, and circadian variations of SCA and SCDCA were also negligible. Suckling calves had much lower SCA levels (2.3 (+/- 1.0) mumol/l before feeding than cows. This initial concentration rose to 10.3 (+/- 2.9) mumol/l 1 h after feeding and returned to 5.0 (+/- 2.1) mumol/l 3 h later. Like cows, horses showed no appreciate difference between pre- and post-feeding levels of SCA (2.2 (+/- 1.2) mumol/l) and SCDCA (1.1 (+/- 0.3) mumol/l). Unlike bovines, pigs and dogs showed a considerable increase in the serum levels of the primary bile acids after feeding.(ABSTRACT TRUNCATED AT 250 WORDS)
Publication Date: 1991-02-01 PubMed ID: 2026118
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Summary

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This research investigates the levels of the two primary bile acids, cholic acid and chenodeoxycholic acid, in the blood serum of cattle, horses, swine, and dogs. Bile acid levels varied in cattle based on their reproductive status, feed consumption had no influence on these levels, while feeding led to considerable increases in pigs and dogs.

Study on Bile Acids in Various Animals

  • The main focus of the research was to determine the levels of two primary bile acids – cholic acid (CA) and chenodeoxycholic acid (CDCA) – in several animals including cattle, horses, swine, and dogs. These levels were measured by a method called radioimmunoassay.
  • Bile acids are critical in the digestion process, helping to break down fats in the intestine. Understanding the levels in various species assists in gaining insights into their metabolic and digestive health.

Variation of Bile Acid Levels in Cattle

  • In cows, the serum levels of CA and CDCA varied according to their reproductive status. The research found different mean levels of these acids in dry cows (those not producing milk), freshly calved dams (cows that had just given birth), and lactating cows.
  • Interestingly, the bile acid levels in cows were not influenced by their feed consumption. Similarly, there was no significant day-to-day variation in the levels of these acids.

Bile Acid Levels in Calves, Horses, Pigs, and Dogs

  • The research also indicated that calves had lower serum levels of cholic acid before feeding than cows. However, these levels increased shortly after feeding.
  • Unlike calves, no noticeable differences were found in the pre-and post-feeding levels of cholic and chenodeoxycholic acids in horses.
  • Different to cattle and horses, both pigs and dogs showed a significant increase in the serum levels of the primary bile acids after consuming food. This indicates how the metabolic responses of different species can vary.

Cite This Article

APA
Karsai F, Szaniszló F, Pethes G. (1991). [Blood serum level of primary bile acids in cattle, horses, swine and dogs]. Dtsch Tierarztl Wochenschr, 98(2), 60-63.

Publication

ISSN: 0341-6593
NlmUniqueID: 7706565
Country: Germany
Language: ger
Volume: 98
Issue: 2
Pages: 60-63

Researcher Affiliations

Karsai, F
  • Lehrstuhl und der Klinik für Innere Medizin, Veterinärmedizinischen Universität Budapest.
Szaniszló, F
    Pethes, G

      MeSH Terms

      • Animals
      • Bile Acids and Salts / blood
      • Cattle / blood
      • Chenodeoxycholic Acid / blood
      • Cholic Acid
      • Cholic Acids / blood
      • Dogs / blood
      • Female
      • Horses / blood
      • Male
      • Pregnancy
      • Reference Values
      • Swine / blood

      Citations

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