Breeding-induced endometritis in mares.
Abstract: Endometritis is a common cause of infertility in broodmares. In the past, the condition was believed to be exclusively the result of bacterial contamination of the uterus. Treatment strategies were focused on preventing bacteria from entering the uterus and on treating mares with signs of endometritis with antibiotics. More recent research on uterine defense mechanisms has increased our understanding of the pathophysiology of equine endometritis. Additional causative agents have been identified, and we have learned to separate uterine infections and a physiologic breeding-induced endometritis resulting from uterine exposure to semen.vi
Publication Date: 2006-11-30 PubMed ID: 17129798DOI: 10.1016/j.cveq.2006.07.003Google Scholar: Lookup
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Summary
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The research article investigates endometritis in mares, a common cause of infertility, which was previously believed to be caused solely by bacterial contamination. Recent findings on uterine defense mechanisms have expanded understanding on the causes and different types of endometritis, including breeding-induced endometritis induced by semen exposure.
Background on Endometritis in Mares
- The research focuses on the condition of endometritis in mares, which is a common cause for infertility in these animals. This condition was traditionally thought to be caused by bacterial contamination within the uterus of the mare.
- Prior to this study, treatment strategies were therefore aimed primarily at preventing bacteria from infiltrating the uterus, and providing antibiotics to mares exhibiting signs of endometritis.
Uterine Defense Mechanisms and Pathophysiology of Equine Endometritis
- Investigating more recent advancements in research around uterine defense mechanisms shaped the direction of the researchers’ investigations into endometritis in mares.
- The work delves into the pathophysiology of equine endometritis, which pertains to how the disorder develops and affects the normal functioning of a mare’s uterus. Gaining insights into this aspect not only helps in understanding the disease process in a more comprehensive manner but also potentially enables an enhancement in treatment methods.
New Understanding on the Causes of Equine Endometritis
- The research was able to uncover a broader range of causative agents triggering endometritis in mares than previously understood. This suggests that the problem would require more widespread preventive measures than solely focusing on bacterial defilement.
- An important distinction also emerged from the study about the difference between uterine infections and a physiological kind of endometritis that occurs due to exposure to semen during breeding, termed as ‘breeding-induced endometritis’.
- The differentiation between these types of endometritis is vital in devising effective therapy and preventive measures for mares, potentially improving their fertility outcomes.
Cite This Article
APA
Troedsson MH.
(2006).
Breeding-induced endometritis in mares.
Vet Clin North Am Equine Pract, 22(3), 705-712.
https://doi.org/10.1016/j.cveq.2006.07.003 Publication
Researcher Affiliations
- Department of Large Animal Clinical Science, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610-0136, USA. troedsson@mail.vetmed.ufl.edu
MeSH Terms
- Animals
- Breeding
- Endometritis / diagnosis
- Endometritis / microbiology
- Endometritis / physiopathology
- Endometritis / veterinary
- Female
- Horse Diseases / diagnosis
- Horse Diseases / microbiology
- Horse Diseases / physiopathology
- Horses
- Male
- Semen / physiology
Citations
This article has been cited 15 times.- Hallman I, Karikoski N, Kareskoski M. The effects of obesity and insulin dysregulation on mare reproduction, pregnancy, and foal health: a review.. Front Vet Sci 2023;10:1180622.
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- Canisso IF, Segabinazzi LGTM, Fedorka CE. Persistent Breeding-Induced Endometritis in Mares - a Multifaceted Challenge: From Clinical Aspects to Immunopathogenesis and Pathobiology.. Int J Mol Sci 2020 Feb 20;21(4).
- Christoffersen M, Woodward E, Bojesen AM, Jacobsen S, Petersen MR, Troedsson MH, Lehn-Jensen H. Inflammatory responses to induced infectious endometritis in mares resistant or susceptible to persistent endometritis.. BMC Vet Res 2012 Mar 29;8:41.
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