Cardiac Biomarker Responses to Acute Exercise in Show Jumping Horses.
Abstract: Cardiac biomarkers are useful to identify cardiac muscle variations in human and equine medicine. The aim of this study was to investigate the acute effect of a bout of show jumping training on serum activity of cardiac and muscular biomarkers in healthy athletic horses to include cardiac troponin (cTnI), myoglobin (MB), aspartate amino transferase (AST), alanine amino transferase (ALT), creatine phosphokinase (CPK) and lactate dehydrogenase (LDH). Serum samples were collected from seven Italian Saddle horses (three geldings and four mares; 10 ± 3 years; mean body weight 480 ±70 kg), regularly trained for show jumping at rest, immediately after exercise (show jumping simulate trial) and during the recovery period (30 and 60 min after exercise). ANOVA was applied to all parameters, and Pearson correlation coefficient t (r) evaluated. Immediately after exercise there was an increase in cTnI (P < .01), MB (P < .01), and CPK (P < .005); a positive correlation between cTnI and AST and between AST and LDH; and a negative correlation between cTnI and ALT and between ALT and CPK. Thirty minutes after exercise, there was a positive correlation between AST and ALT and between AST and LDH, while 60 mintues after exercise, there was a positive correlation between MB and LDH and a negative correlation between AST and CPK. The results obtained demonstrate the cardiac and muscular response to short-term intense exercise show jumping exercise.
Copyright © 2023 Elsevier Inc. All rights reserved.
Publication Date: 2023-07-06 PubMed ID: 37422139DOI: 10.1016/j.jevs.2023.104882Google Scholar: Lookup
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- Journal Article
Summary
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The research article discusses a study that evaluates the changes in cardiac and muscular biomarkers in healthy athletic horses after participating in a round of show jumping training.
Introduction
- The study focuses on understanding how acute physical exercise, specifically show jumping, impacts the levels of certain cardiac biomarkers.
- These biomarkers include cardiac troponin (cTnI), myoglobin (MB), aspartate amino transferase (AST), alanine amino transferase (ALT), creatine phosphokinase (CPK), and lactate dehydrogenase (LDH). They play a crucial role in diagnosing the variations in cardiac muscle both in humans and horses.
Methodology
- Seven Italian Saddle horses which were regularly trained for show-jumping participated in the research. These included three geldings and four mares with a mean body weight of 480 ±70 kg and age 10 ± 3 years.
- Serum samples were collected from the horses at three different times: at rest before the exercise, immediately after the jumping trial, and during the recovery period (30 minutes and 60 minutes after the exercise).
Results
- Right after the exercise, there was a significant increase in the biomarkers cTnI, MB, and CPK.
- At this time, positive correlations were found between cTnI and AST, and between AST and LDH. Negative correlations were identified between cTnI and ALT, and between ALT and CPK.
- Elaborating further, a positive correlation means that as one marker increases, the other does as well, and a negative correlation suggests that as one marker increases, the other decreases.
- 30 minutes after the exercise, positive correlations were observed between AST and ALT, and between AST and LDH.
- At the 60-minute recovery mark, there was a positive correlation between MB and LDH, and a negative correlation between AST and CPK.
Conclusion
- The results from the study indicate that the cardiac and muscular system of the horses respond to short-term intense exercises like show jumping.
- The changes and correlations in specific biomarkers provide insight into the physiological stress endured by the horse’s body, which can be valuable information for improving training methods and ensuring optimal horse health.
Cite This Article
APA
Fazio F, Aragona F, Piccione G, Pino C, Giannetto C.
(2023).
Cardiac Biomarker Responses to Acute Exercise in Show Jumping Horses.
J Equine Vet Sci, 128, 104882.
https://doi.org/10.1016/j.jevs.2023.104882 Publication
Researcher Affiliations
- Department of Veterinary Sciences, Via Palatucci snc, University of Messina, 98168, Messina, Italy.
- Department of Veterinary Sciences, Via Palatucci snc, University of Messina, 98168, Messina, Italy. Electronic address: francesca.aragona@unime.it.
- Department of Veterinary Sciences, Via Palatucci snc, University of Messina, 98168, Messina, Italy.
- Diagnostica dei Verdi, Messina, Italy.
- Department of Veterinary Sciences, Via Palatucci snc, University of Messina, 98168, Messina, Italy.
MeSH Terms
- Horses
- Animals
- Male
- Humans
- Female
- Physical Conditioning, Animal
- Creatine Kinase
- Sports
- Biomarkers
Conflict of Interest Statement
Declaration of Competing Interest The authors declare that they have no conflict of interest. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
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