Cardiac cycle length variability in ponies at rest and during exercise.
- Journal Article
- Research Support
- U.S. Gov't
- P.H.S.
Summary
This research investigates how the variation in heartbeats behaves in ponies under varying conditions, such as resting, exercising, and exercising after premedication with atropine. The study finds that exercise significantly reduces these variations, and this effect is pronounced when ponies are premedicated with atropine. The study concludes that the parasympathetic system primarily drives cardiac cycle length variation in ponies.
Overview of the Research
The research conducted here was aimed at understanding the variability in the length of the cardiac cycle in ponies. Three specific situations were considered:
- When the ponies were at rest without any prior medication
- When the ponies were put under strenuous exercise without any prior medication
- When the ponies were put under strenuous exercise post-premedication with a drug called atropine
Three indexes were taken into account to measure these variations: the average cardiac cycle length in milliseconds, the standard deviation of cardiac cycle length, and the coefficient of variation of cycle length.
Research Findings
The results disclosed significant fluctuations in the cardiac cycle of ponies under different conditions.
- In a resting state without premedication, cardiac cycle length manifested considerable variability; with an average length of 1112 milliseconds, with a standard deviation and a coefficient of variation indicating the degree of variation.
- With strenuous exercise, a significant decrease was observed in all three indexes, indicating that physical activity helped regulate the pony’s cardiac rhythm.
- Premedication with atropine followed by exercise also significantly diminished the resting cardiac cycle length and its variability, implying the critical influence of atropine on the pony’s cardiac rhythm.
Conclusion and Implications
The research concluded that the variability in the cardiac cycle length of ponies is chiefly driven by the parasympathetic system. The absence of significant differences across the indexes during exercise (both with and without premedication) and at rest after atropine administration attests to this conclusion. Thus, the study provides significant insight into understanding the cardiac cycling length of ponies under varying conditions, contributing to better cardiovascular health management in these animals.
Cite This Article
Publication
Researcher Affiliations
- John M. Dalton Research Center, University of Missouri-Columbia 65211.
MeSH Terms
- Animals
- Atropine / pharmacology
- Heart Rate / physiology
- Horses / physiology
- Myocardial Contraction / physiology
- Parasympathetic Nervous System / physiology
- Physical Exertion / physiology
- Rest / physiology
- Ventricular Function, Left / physiology
Grant Funding
- F32-HL-06999 / NHLBI NIH HHS
- R01-HL-29007 / NHLBI NIH HHS
- T32-HL-07187 / NHLBI NIH HHS
Citations
This article has been cited 2 times.- Szabó C, Vizesi Z, Vincze A. Heart Rate and Heart Rate Variability of Amateur Show Jumping Horses Competing on Different Levels.. Animals (Basel) 2021 Mar 4;11(3).
- Billman GE. Heart rate variability - a historical perspective.. Front Physiol 2011;2:86.