Cardiovascular effects of thoracic compression in horses subjected to euthanasia.
Abstract: Six horses scheduled for euthanasia were instrumented for the measurement of blood flow by thermodilution, pulmonary arterial, right atrial and arterial blood pressures and collection of arterial blood for pH and blood gas analysis. The horses were anaesthetised with intravenous (iv) thiamylal sodium (10 mg/kg) and placed in right lateral recumbency. After euthanasia with an overdose of pentobarbitone sodium (100 mg/kg, iv) and loss of the electrocardiogram and arterial pulse pressure, thoracic compression at rates of 40, 60 and 80 compressions/min was instituted. Thoracic compression was accomplished by an investigator who delivered a blow to the chest wall with his knee while dropping from a standing or crouching position. Compression rates of 40, 60 and 80/min produced blood flows of 5.65 +/- 0.5, 6.33 +/- 1.11 and 8.28 +/- 2.16 litres/min, respectively. Compression rates of 80/min produced significantly (P < 0.05) greater blood flows and mean arterial blood pressures than did slower rates. The blood flows produced by 80 thoracic compressions/min were approximately 50% of those reported for deeply anaesthetised horses and while not sufficient to sustain life might be used to prolong life in order to facilitate distribution of resuscitative drugs to vital tissues.
Publication Date: 1993-07-01 PubMed ID: 8354212DOI: 10.1111/j.2042-3306.1993.tb02964.xGoogle Scholar: Lookup
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- Journal Article
Summary
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This research examined the cardiovascular impacts of thoracic compression on horses during euthanasia. The results demonstrate that high rates of chest compressions show significant increases in blood flow and blood pressure levels, which may potentially be used to prolong life to aid the delivery of resuscitative drugs.
Objective of the Research
- The study aimed to investigate the cardiovascular effects of thoracic compression on horses undergoing euthanasia. It’s a type of study that seeks to understand the physiological changes that occur during the euthanasia process.
Methodology
- Six horses scheduled for euthanasia were equipped with monitoring equipment to measure blood flow, arterial and right atrial pressure, as well as facilitate arterial blood collection for pH and blood gas analysis.
- Each horse was then anaesthetized using intravenous thiamylal sodium and laid on their right side.
- Euthanasia was carried out using an overdose of pentobarbitone sodium. After the loss of heartbeat and arterial pulse pressure, various rates of thoracic compression were applied.
- An investigator performed the chest compressions by delivering a knee blow to the horse’s chest from a standing or crouching position. This was done at rates of 40, 60, and 80 compressions per minute.
Results and Conclusion
- Compression rates of 40, 60, and 80 per minute resulted in blood flows of 5.65, 6.33, and 8.28 litres/min, respectively.
- Compression rates of 80 compressions/minute significantly increased blood flow and mean arterial blood pressure compared to slower rates.
- The blood flows caused by 80 compressions/minute were approximately 50% of those reported for deeply anaesthetized horses.
- Although insufficient to sustain life, these findings suggest that high rates of chest compressions might be used to temporarily prolong life for facilitating the distribution of resuscitative drugs to vital tissues.
Cite This Article
APA
Hubbell JA, Muir WW, Gaynor JS.
(1993).
Cardiovascular effects of thoracic compression in horses subjected to euthanasia.
Equine Vet J, 25(4), 282-284.
https://doi.org/10.1111/j.2042-3306.1993.tb02964.x Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210.
MeSH Terms
- Animals
- Blood Flow Velocity
- Blood Pressure
- Cardiopulmonary Resuscitation / veterinary
- Euthanasia / veterinary
- Heart Arrest / therapy
- Heart Arrest / veterinary
- Horse Diseases / therapy
- Horses / physiology
- Pulmonary Artery / physiology
- Regional Blood Flow
Citations
This article has been cited 2 times.- Conde Ruiz C, Junot S. Successful Cardiopulmonary Resuscitation in a Sevoflurane Anaesthetized Horse That Suffered Cardiac Arrest at Recovery. Front Vet Sci 2018;5:138.
- Sakiyama-Elbert SE. Incorporation of heparin into biomaterials. Acta Biomater 2014 Apr;10(4):1581-7.
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