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Veterinary surgery : VS2009; 38(8); 998-1005; doi: 10.1111/j.1532-950X.2009.00589.x

Carpometacarpal osteoarthritis in thirty-three horses.

Abstract: To describe signalment, clinical, and radiographic changes associated with carpometacarpal osteoarthritis (CMC-OA) and to report long-term outcome. Methods: Case series. Methods: Horses (n=33) with CMC-OA. Methods: Medical records (1992-2007) of horses diagnosed with CMC-OA were reviewed and signalment, clinical, and radiographic findings retrieved. Owners were contacted for information on the impact of lameness on intended use, response to treatment, progression of lameness, outcome, and owner satisfaction with response to treatment. Results: CMC-OA identified in 39 limbs, occurred predominantly in middle-aged and older Quarter Horses and Arabians, and caused severe lameness that prevented normal use. Characteristic swelling was centered over the 2nd metacarpal bone/2nd carpal bone articulation. Radiographic changes consisted of proliferative new bone, narrowed joint space, and subchondral lysis. Of 20 horses with follow-up, 7 of 14 treated horses were euthanatized within 4 years and 4 of 5 nontreated horses within 3 years. Response to treatment was short lived and considered very poor by most owners. Conclusions: CMC-OA seemingly occurs primarily in Quarter Horses and Arabians in our region. Response to conservative treatment is very poor and short-lived with most horses being euthanatized. Conclusions: Conventional treatment methods are unsuccessful for treating CMC-OA.
Publication Date: 2009-12-19 PubMed ID: 20017859DOI: 10.1111/j.1532-950X.2009.00589.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This research examines the characteristics, clinical symptoms, and radiographic changes associated with Carpometacarpal Osteoarthritis (CMC-OA) in horses, and assesses the long-term outcome of this condition. The study concludes that conventional treatment methods have been largely unsuccessful, with majority of the horses ultimately euthanized.

Objectives and Methodology

The primary objectives of this study were:

  • To outline the signalment (demographic information of animals including breed, age, sex), clinical symptoms, and radiographic indicators associated with CMC-OA in horses.
  • To assess the long-term outcomes of this condition.

The study was based on a review of medical records of 33 horses diagnosed with CMC-OA during the period from 1992 to 2007. Information collected from these records related to signalment, clinical findings, and radiographic changes. Further data was obtained by contacting owners for update on the horses’ lameness progression, response to treatment, and overall outcome.

Findings

The significant findings from the study were:

  • CMC-OA was identified in 39 limbs and commonly found in middle-aged and older Quarter Horses and Arabians.
  • Symptoms included severe lameness that hindered normal functioning, along with characteristic swelling located over the articulation between the 2nd metacarpal and 2nd carpal bones.
  • Radiographic changes observed included new bone proliferation, narrowed joint spaces, and subchondral lysis (destruction of subchondral bone).
  • Out of 20 horses that were followed up, 7 out of 14 treated horses were euthanized within 4 years and 4 out of 5 untreated horses within 3 years, indicating a severe impact of the condition.

Conclusion

Based on the study’s findings, the researchers concluded that:

  • CMC-OA appears to primarily affect Quarter Horses and Arabians in the studied region.
  • The response to conservative treatment for CMC-OA was typically poor and short-lived. Consequently, many horses had to be euthanized.
  • Conventional treatment methods have so far been unsuccessful for treating horses with CMC-OA.

Cite This Article

APA
Panizzi L, Barber SM, Lang HM, Carmalt JL. (2009). Carpometacarpal osteoarthritis in thirty-three horses. Vet Surg, 38(8), 998-1005. https://doi.org/10.1111/j.1532-950X.2009.00589.x

Publication

ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 38
Issue: 8
Pages: 998-1005

Researcher Affiliations

Panizzi, Luca
  • Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada. luca.panizzi@usask.ca
Barber, Spencer M
    Lang, Hayley M
      Carmalt, James L

        MeSH Terms

        • Age Factors
        • Animals
        • Disease Progression
        • Horse Diseases / diagnosis
        • Horse Diseases / pathology
        • Horses
        • Lameness, Animal / diagnosis
        • Osteoarthritis / diagnosis
        • Osteoarthritis / pathology
        • Osteoarthritis / veterinary
        • Prognosis

        Citations

        This article has been cited 2 times.
        1. Mayet A, Zablotski Y, Roth SP, Brehm W, Troillet A. Systematic review and meta-analysis of positive long-term effects after intra-articular administration of orthobiologic therapeutics in horses with naturally occurring osteoarthritis. Front Vet Sci 2023;10:1125695.
          doi: 10.3389/fvets.2023.1125695pubmed: 36908512google scholar: lookup
        2. Doan R, Cohen ND, Sawyer J, Ghaffari N, Johnson CD, Dindot SV. Whole-genome sequencing and genetic variant analysis of a Quarter Horse mare. BMC Genomics 2012 Feb 17;13:78.
          doi: 10.1186/1471-2164-13-78pubmed: 22340285google scholar: lookup