Characterization of cytochrome b diversity in Chinese domestic horses.
Abstract: Previous mitochondrial DNA (mtDNA) D-loop and microsatellite studies have shown that Chinese horses have multiple maternal origins and high genetic diversity. To better characterize maternal genetic origins and diversity of Chinese domestic horses, we conducted a comprehensive analysis of 407 complete 1140 bp sequences of the horse mitochondrially encoded cytochrome b (CYTB) gene, including 323 horses from 13 Chinese indigenous breeds and 84 reference sequences from GenBank. A total of 114 haplotypes were identified, of which 73 appeared among the 13 Chinese horse breeds. The high mitochondrially encoded cytochrome b haplotypic diversity suggests multiple maternal origins in Chinese horses.
© 2011 The Authors, Animal Genetics © 2011 Stichting International Foundation for Animal Genetics.
Publication Date: 2011-12-21 PubMed ID: 22497593DOI: 10.1111/j.1365-2052.2011.02298.xGoogle Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research investigates the genetic origins and diversity of Chinese domestic horses, revealing multiple maternal origins and a high degree of genetic diversity as evidenced by data drawn from analysis of the mitochondrially encoded cytochrome b (CYTB) gene.
Introduction
- The authors begin by noting that previous studies using mitochondrial DNA (mtDNA) D-loop and microsatellites found high genetic diversity and multiple maternal origins in Chinese horses.
- The aim of their research was to further investigate this by analyzing the mitochondrially encoded cytochrome b (CYTB) gene in Chinese domestic horses.
Methods
- A comprehensive study was conducted using 407 complete 1140 bp sequences of the CYTB gene.
- The sample included 323 horses from 13 different Chinese indigenous breeds, alongside 84 reference sequences obtained from a public scientific database, GenBank.
Results
- A total of 114 haplotypes were identified from this analysis.
- 73 of these haplotypes were found in the 13 different Chinese horse breeds.
- This showed a high degree of haplotypic diversity in the CYTB gene amongst the Chinese horses.
Conclusion
- This high haplotypic diversity reaffirms the conclusion that there are multiple maternal origins in Chinese horses.
- This research provides further genomic evidence to back previous research and contributes to a more comprehensive understanding of the genetic origins and diversity of Chinese domestic horses.
Cite This Article
APA
Yue XP, Qin F, Campana MG, Liu DH, Mao CC, Wang XB, Lan XY, Chen H, Lei CZ.
(2011).
Characterization of cytochrome b diversity in Chinese domestic horses.
Anim Genet, 43(5), 624-626.
https://doi.org/10.1111/j.1365-2052.2011.02298.x Publication
Researcher Affiliations
- Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi 712100, China.
MeSH Terms
- Animals
- Base Sequence
- China
- Cytochromes b / genetics
- DNA, Mitochondrial / genetics
- Female
- Haplotypes
- Horses / genetics
- Molecular Sequence Data
- Phylogeny
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Sequence Alignment
Citations
This article has been cited 5 times.- Liu S, Fu C, Yang Y, Zhang Y, Ma H, Xiong Z, Ling Y, Zhao C. Current genetic conservation of Chinese indigenous horses revealed with Y-chromosomal and mitochondrial DNA polymorphisms.. G3 (Bethesda) 2021 Feb 9;11(2).
- Liu S, Yang Y, Pan Q, Sun Y, Ma H, Liu Y, Wang M, Zhao C, Wu C. Ancient Patrilineal Lines and Relatively High ECAY Diversity Preserved in Indigenous Horses Revealed With Novel Y-Chromosome Markers.. Front Genet 2020;11:467.
- Ning T, Ling Y, Hu S, Ardalan A, Li J, Mitra B, Chaudhuri TK, Guan W, Zhao Q, Ma Y, Savolainen P, Zhang Y. Local origin or external input: modern horse origin in East Asia.. BMC Evol Biol 2019 Nov 27;19(1):217.
- Sziszkosz N, Mihók S, Jávor A, Kusza S. Genetic diversity of the Hungarian Gidran horse in two mitochondrial DNA markers.. PeerJ 2016;4:e1894.
- Cardinali I, Lancioni H, Giontella A, Capodiferro MR, Capomaccio S, Buttazzoni L, Biggio GP, Cherchi R, Albertini E, Olivieri A, Cappelli K, Achilli A, Silvestrelli M. An Overview of Ten Italian Horse Breeds through Mitochondrial DNA.. PLoS One 2016;11(4):e0153004.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
