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Home / Equine Research Bank / Vet Surg / Chitosan-based agent use for hemostasis after cryptorchidect...
Veterinary surgery : VS2020; 49(4); 758-763; doi: 10.1111/vsu.13363

Chitosan-based agent use for hemostasis after cryptorchidectomy in a horse.

Abstract: To document marked hemorrhage as a complication of inguinal cryptorchidectomy and its successful treatment with a novel chitosan-based hemostatic agent. Methods: Case report. Methods: One healthy 5-year old quarter horse cryptorchid. Methods: The horse was presented for routine unilateral cryptorchidectomy after prior hemicastration. An inguinal approach was made to the abdomen, and the right external pudendal artery was lacerated at the level of the internal inguinal ring, requiring multiple anesthetic events over a 2-week period in attempts to control hemorrhage. A chitosan-based hemostatic agent was packed into the wound to gain control. Results: Chitosan granules placed in the wound successfully controlled the hemorrhage, whereas the use of gauze packing alone failed. There were no immediate or long-term complications to the chitosan granules; the horse was doing well 18 months postoperatively, and the client was satisfied with the outcome. Conclusions: Major hemorrhage was demonstrated from the external pudendal artery and caused difficulties because it occurred deep within the inguinal canal during an inguinal cryptorchidectomy. A chitosan-based hemostatic agent was successfully used to achieve hemostasis. Conclusions: The external pudendal artery should be avoided in the medial commissure of the inguinal canal. The use of chitosan-based hemostatic agents warrants further investigation in horses because these products may be useful for controlling major hemorrhage from various causes in equine practice.
© 2020 The American College of Veterinary Surgeons.
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Publication Date: 2020-01-09 PubMed ID: 31916606DOI: 10.1111/vsu.13363Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research presents a case study of controlling severe bleeding during cryptorchidectomy in a horse using a chitosan-based hemostatic agent. The agent worked efficiently, whereas traditional gauze packing failed to stop the hemorrhage, indicating its potential use in equine surgeries dealing with major blood loss.

Research Methodology

  • The research revolves around a case study involving a healthy 5-year old quarter horse undergoing cryptorchidectomy – a surgical removal of an undescended testicle from the inguinal canal.
  • The horse had already undergone a prior hemicastration. During the cryptorchidectomy, the horse’s right external pudendal artery was accidentally lacerated leading to a significant hemorrhage.
  • After unsuccessful attempts to control the bleeding over a 2-week period using traditional methods such as gauze packing, a chitosan-based haemostatic agent was employed, which was packed into the wound.

Results

  • The study reported a successful control of the severe bleeding by using chitosan granules placed directly into the wound. This was after multiple failed attempts to stop the hemorrhage with regular gauze packing.
  • The treatment didn’t manifest any immediate or long-term complications. The horse was healthy and well 18 months post-operatively, showcasing a successful application of the chitosan-based hemostatic agent.

Conclusions

  • The research illustrated a complex stewardship caused due to major bleeding from the external pudendal artery, occurring deep within the inguinal canal during the cryptorchidectomy procedure.
  • The chitosan-based hemostatic agent was endorsed for its successful use in achieving hemostasis or bleeding control in this specific case.
  • The researchers concluded that external pudendal artery should be avoided during surgeries in the inguinal canal since it presents risk of major blood loss.
  • Given the successful outcome of the chitosan-based hemostatic agent in controlling major hemorrhage, the study advocates for further research on these agents. The possibility of using chitosan-based agents can be a significant addition to bleeding control methods in equine surgical practice.

Cite This Article

APA
Tucker ML, Wilson DG, Barber SM. (2020). Chitosan-based agent use for hemostasis after cryptorchidectomy in a horse. Vet Surg, 49(4), 758-763. https://doi.org/10.1111/vsu.13363

Publication

Veterinary surgery : VS
ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 49
Issue: 4
Pages: 758-763

Researcher Affiliations

Tucker, Michelle L
  • Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Wilson, David G
  • Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Barber, Spencer M
  • Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

MeSH Terms

  • Animals
  • Chitosan / therapeutic use
  • Cryptorchidism / blood
  • Cryptorchidism / surgery
  • Cryptorchidism / veterinary
  • Hemostasis
  • Hemostatics / therapeutic use
  • Horse Diseases / blood
  • Horse Diseases / surgery
  • Horses
  • Male

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