Cholangiohepatitis and pancreatitis secondary to severe gastroduodenal ulceration in a foal.
Abstract: A 2-month-old foal was presented with clinical signs of colic. Gastroduodenal ulceration was suspected. A poor response to medical treatment and signs of gastroduodenal obstruction led to celiotomy and an attempted bypass procedure. The foal was euthanized and postmortem examination revealed gastric ulceration, segmental duodenal stenosis, and severe chronic cholangiohepatitis and pancreatitis.
Publication Date: 2003-10-04 PubMed ID: 14524632PubMed Central: PMC340274
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Case Reports
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research details a case where a 2-month-old foal, presented with colic symptoms, was found to suffer from severe gastroduodenal ulceration leading to cholangiohepatitis and pancreatitis.
Case presentation and initial diagnosis
- The main focus of this paper is the case of a 2-month-old foal that was reported to have clinical signs of colic. The attending veterinarians initially suspected gastroduodenal ulceration, a condition that involves sores or ulcers forming in the stomach and first part of the small intestine, due to its symptoms.
Medical intervention and surgical procedure
- The foal did not respond well to the medical treatments given for the suspected ulceration. Its health worsened due to signs of gastroduodenal obstruction.
- Due to the lack of response to medical treatment and worsening health, a surgical intervention, specifically a celiotomy, was carried out. This is a surgical incision into the abdominal cavity used to examine internal organs and potentially rectify internal issues such as blockages.
- During surgery, an attempted bypass procedure was performed to counteract the obstruction. A bypass procedure involves creating a new pathway for food to pass if the usual pathway is blocked.
Euthanasia and postmortem findings
- Despite these efforts, the foal’s condition could not be significantly improved upon, leading to the decision to euthanize the animal for humane reasons.
- A postmortem examination was carried out to better understand the root of the severe health concerns. The autopsy revealed that the foal had been suffering from gastric ulceration, as initially suspected, alongside segmental duodenal stenosis – a narrowing of a portion of the duodenum (the first part of the small intestine).
- Additionally, the examination found severe chronic cholangiohepatitis and pancreatitis. Cholangiohepatitis is inflammation of the bile ducts and liver, while pancreatitis is inflammation of the pancreas. These conditions were serious and closely linked to the animal’s deteriorating health and ultimate death.
Significance of the research
- This research sheds light on how severe gastroduodenal ulceration in a young animal can lead to other serious health complications, such as cholangiohepatitis and pancreatitis. It underlines the need for thorough examination and aggressive treatment strategies in such cases.
- This case study also underlines the importance of early diagnosis followed by well-planned medical or surgical intervention. Here, despite prompt medical and surgical interventions, the foal could not be saved, emphasising the severity of the complex combination of medical conditions.
Cite This Article
APA
Buote M.
(2003).
Cholangiohepatitis and pancreatitis secondary to severe gastroduodenal ulceration in a foal.
Can Vet J, 44(9), 746-748.
Publication
Researcher Affiliations
- Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3. melaniebuote@yahoo.com
MeSH Terms
- Animals
- Animals, Newborn
- Cholangitis / etiology
- Cholangitis / veterinary
- Colic / etiology
- Colic / veterinary
- Fatal Outcome
- Hepatitis, Animal / etiology
- Horse Diseases / diagnosis
- Horse Diseases / surgery
- Horses
- Male
- Pancreatitis / etiology
- Pancreatitis / veterinary
- Peptic Ulcer / complications
- Peptic Ulcer / surgery
- Peptic Ulcer / veterinary
References
This article includes 10 references
- Murray MJ, Grodinsky BS, Cowles RR. Endoscopic evaluation of changes in gastric lesions of Thoroughbred foals.. J Am Vet Med Assoc 1990;196:1623–1627.
- Murray MJ, Murray CM, Sweeny HJ. Prevalence of gastric lesions in foals without signs of gastric disease: an endoscopic survey.. Equine Vet J 1990;22:6–8.
- Becht JL, Byars TD. Gastroduodenal ulceration in foals.. Equine Vet J 1986;18:307–312.
- Orsini JA, Donawick WJ. Hepaticojejunostomy for treatment of common hepatic duct obstructions associated with duodenal stenosis in two foals.. Vet Surg 1989;18:34–38.
- Palmer JE. Gastrointestinal disease of foals.. Vet Clin North Am Equine Pract 1985;1:151–168.
- Acland HM, Gunson DE, Gillette DM. Ulcerative duodenitis in foals.. Vet Pathol 1983;20:653–661.
- Berschneider HM, Blikslager AT, Roberts MC. Role of duodenal reflux in nonglandular reflux disease in mature horses.. Equine Vet J 1999;29:24–29.
- Murray MJ. Pathophysiology of peptic disorders in foals and horses: a review.. Equine Vet J 1999;29:14–18.
- Lilley CW, Beeman GM. Gastric dilation associated with acute necrotizing pancreatitis.. Equine Pract 1981;3:8–15.
- Aronoff N, Keegan KG, Johnson PF. Management of pyloric obstruction in a foal.. J Am Vet Med Assoc 1997;210:902–907.
Citations
This article has been cited 1 times.- Gomez DE, Radtke CL, Russell LA, Lopez A, Wichtel MW. Acute pancreatitis following granulosa cell tumor removal in a mare. Can Vet J 2015 Oct;56(10):1049-52.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists