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The Veterinary clinics of North America. Equine practice1997; 13(1); 145-168; doi: 10.1016/s0749-0739(17)30261-4

Chronic exertional rhabdomyolysis.

Abstract: This article presents a brief description of what is known about the cause and pathogenesis of chronic intermittent rhabdomyolysis in horses. Clinically applicable diagnostic tests and published results in affected horses, prophylaxis, and treatment of the acute case are discussed.
Publication Date: 1997-04-01 PubMed ID: 9106349DOI: 10.1016/s0749-0739(17)30261-4Google Scholar: Lookup
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Summary

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The research article offers an insight into chronic intermittent rhabdomyolysis in horses, its cause, how it develops, how it can be diagnosed, prevented, and treated.

Understanding Chronic Intermittent Rhabdomyolysis

Chronic intermittent rhabdomyolysis is a muscle disorder frequently observed in horses. It leads to the breakdown of muscle fibres resulting in the release of their contents into the bloodstream. This disorder can be intermittent with episodes separated by periods of normalcy.

  • This article provides an overview of the current knowledge concerning the cause and pathogenesis, which is the biological mechanism that leads to the disease.
  • It further seeks to understand the root of the problem to develop effective strategies for prevention and treatment.

Diagnostic Tests and Results

The research also discusses different detection procedures for diagnosing chronic intermittent rhabdomyolysis in horses and reveals published results in affected subjects.

  • Certain clinically applicable diagnostic tests which are used to confirm the presence of the disorder are examined in the paper.
  • These tests help identify rhabdomyolysis symptoms such as markedly elevated serum muscle enzyme activity and myoglobinuria, which is the presence of myoglobin in urine.

Prevention and Treatment

The article provides guidelines on how to prevent the disease and treat acute cases.

  • In terms of prophylaxis or preventive measures, the paper emphasizes factors such as diet adjustments and improved management of exercise routines.
  • It also discusses various treatment methods for acute rhabdomyolysis cases, which possibly include proper rest, rehydration and pain management strategies. However, the treatment usually depends on the severity of the condition and the horse’s overall health.

This article’s pivotal focus is to amplify research in the field of equine health, particularly towards understanding and managing the chronic intermittent rhabdomyolysis condition. The findings could play a significant role in ensuring the wellbeing of the equine species.

Cite This Article

APA
Beech J. (1997). Chronic exertional rhabdomyolysis. Vet Clin North Am Equine Pract, 13(1), 145-168. https://doi.org/10.1016/s0749-0739(17)30261-4

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 13
Issue: 1
Pages: 145-168

Researcher Affiliations

Beech, J
  • Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, USA.

MeSH Terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Aspartate Aminotransferases / blood
  • Aspartate Aminotransferases / metabolism
  • Chronic Disease
  • Creatine Kinase / blood
  • Creatine Kinase / metabolism
  • Horse Diseases / diagnosis
  • Horse Diseases / etiology
  • Horse Diseases / therapy
  • Horses
  • Myoglobin / blood
  • Myoglobinuria / metabolism
  • Myoglobinuria / veterinary
  • Physical Conditioning, Animal
  • Rhabdomyolysis / diagnosis
  • Rhabdomyolysis / etiology
  • Rhabdomyolysis / veterinary
  • Selenium / blood
  • Vitamin E / blood
  • Vitamin E / physiology
  • Water-Electrolyte Balance

Citations

This article has been cited 1 times.
  1. Breed D, Meyer LCR, Steyl JCA, Goddard A, Burroughs R, Kohn TA. Conserving wildlife in a changing world: Understanding capture myopathy-a malignant outcome of stress during capture and translocation. Conserv Physiol 2019;7(1):coz027.
    doi: 10.1093/conphys/coz027pubmed: 31304016google scholar: lookup