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Journal of veterinary internal medicine2010; 24(5); 1147-1152; doi: 10.1111/j.1939-1676.2010.0573.x

Clinical features and prognostic variables in 109 horses with esophageal obstruction (1992-2009).

Abstract: Esophageal obstruction is common in horses and can result in life-threatening complications. Previous studies have described clinical findings in horses with esophageal obstruction, but there are no reports that attempt to make correlations of clinical findings with outcome. Objective: Specific clinical features of horses with esophageal obstruction are associated with increased likelihood of complications. Methods: One hundred and nine horses with esophageal obstruction. Methods: Retrospective cross-sectional study. All clinical records of horses admitted between April 1992 and February 2009 for esophageal obstruction were reviewed. The association among 24 clinical, hematological, biochemical, therapeutic variables and the likelihood of complications was investigated by a univariable logistic regression model, followed by multivariable analysis. Results: Multiple logistic regression analysis revealed that intact males (P= .02), age >15 years (P < .01), and a need for general anesthesia (P < .01) were associated with the development of complications after an episode of esophageal obstruction. Increased respiratory rate (>22 breaths/min) and moderate or severe tracheal contamination, although not associated with complications as a whole, significantly increased the risk of developing aspiration pneumonia (P≤ .01). Conclusions: Signalment, clinical variables, and endoscopic findings were confirmed as important tools in assessing the severity of the esophageal lesion and pulmonary involvement. Knowledge of risk factors for the development of complications will aid in making informed decisions to optimize treatment and assist in the assessment of prognosis.
Publication Date: 2010-08-12 PubMed ID: 20707844DOI: 10.1111/j.1939-1676.2010.0573.xGoogle Scholar: Lookup
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Summary

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The research article investigates the clinical features and medical variables in horses suffering from esophageal obstruction and how these correspond to increasing chances of complications. The focus is on identifying risk factors to facilitate better treatment decisions and prognosis.

Objective and Methods

The primary goal of the research was to identify specific clinical characteristics in horses with esophageal obstruction that were associated with an increased risk of complications. It was conducted as a retrospective cross-sectional study, where all relevant clinical records of horses, admitted between April 1992 and February 2009 for esophageal obstruction, were reviewed.

  • A total of 109 horses suffering from esophageal obstruction were part of the study.
  • The researchers explored a potential link between 24 clinical, hematological (related to blood and blood-forming organs), biochemical and therapeutic variables, and the likelihood of complications.
  • A univariable logistic regression model, followed by a multivariable analysis, was used for this investigation.

Findings

Based on the applied statistical analysis, the study discovered several potential risk factors associated with the development of complications following an episode of esophageal obstruction.

  • Males that have not been castrated (intact males) were found to be at an increased risk of complications (P= .02).
  • Horses older than 15 years had a higher chance of developing complications (P < .01).
  • A need for general anesthesia also corresponded to an increased complication risk (P < .01).
  • An elevated respiratory rate (>22 breaths/min) or moderate to severe tracheal (related to the windpipe) contamination, significantly raised the risk of developing aspiration pneumonia, a specific complication in this case (P≤ .01).

Conclusion

In summarising the results, the researchers state that clinical variables, the horses’ signalment (facts about the animal such as age, breed, sex), and endoscopic findings are valuable tools in assessing the severity of esophageal lesions and potential lung involvement. By understanding these risk factors, veterinarians can make better-informed treatment decisions and provide a more accurate prognosis for horses with esophageal obstruction.

Cite This Article

APA
Chiavaccini L, Hassel DM. (2010). Clinical features and prognostic variables in 109 horses with esophageal obstruction (1992-2009). J Vet Intern Med, 24(5), 1147-1152. https://doi.org/10.1111/j.1939-1676.2010.0573.x

Publication

ISSN: 0891-6640
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 24
Issue: 5
Pages: 1147-1152

Researcher Affiliations

Chiavaccini, L
  • Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Hassel, D M

    MeSH Terms

    • Acepromazine / therapeutic use
    • Adrenergic alpha-Agonists / therapeutic use
    • Animals
    • Anti-Bacterial Agents / therapeutic use
    • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
    • Cross-Sectional Studies
    • Dopamine Antagonists / therapeutic use
    • Esophageal Diseases / drug therapy
    • Esophageal Diseases / veterinary
    • Female
    • Horse Diseases / drug therapy
    • Horse Diseases / pathology
    • Horses
    • Male
    • Prognosis
    • Retrospective Studies