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Equine veterinary journal1990; 22(3); 180-181; doi: 10.1111/j.2042-3306.1990.tb04243.x

Clinical use of epidural xylazine in the horse.

Abstract: Xylazine was administered into the epidural space of nine horses to facilitate various perineal manipulations (ie rectovaginal laceration repair, replacement of prolapsed rectum and urethral extension). The resulting caudal analgesia was sufficient for all procedures. The duration of analgesia from a single injection of epidural xylazine (0.17 to 0.22 mg/kg bodyweight) was at least 3.5 h. No horses were ataxic during or after the treatment. This trial demonstrates that xylazine given into the epidural space of horses provides prolonged regional analgesia which is sufficient for clinical use.
Publication Date: 1990-05-01 PubMed ID: 2361505DOI: 10.1111/j.2042-3306.1990.tb04243.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This research article explores the use of epidural xylazine, a form of anaesthesia, in horses for various perineal procedures, with findings indicating that it provides lasting and sufficient pain relief without causing unsteady movement in the animals.

Methodology and Procedures

The study involved administering xylazine into the epidural space of nine horses. Using this anesthetic was meant to facilitate various perineal manipulations in the horses. The researchers considered procedures like:

  • Rectovaginal laceration repair
  • Replacement of a prolapsed rectum
  • Urethral extension

Findings and Results

The researchers found that the epidural xylazine provided enough caudal analgesia (pain relief in the lower part of the body) for the horses to undergo all the aforementioned procedures. They noticed that a single injection of epidural xylazine, with dosage varying from 0.17 to 0.22 mg/kg bodyweight, could provide analgesia for at least 3.5 hours. Importantly, no horses displayed any signs of ataxia (lack of muscle control or coordination of voluntary movements) both during and after the treatment.

Conclusions

The trial concluded that xylazine, when administered into the epidural space of horses, provides prolonged regional analgesia. This level of analgesia was found to be sufficient for clinical use, indicating that xylazine could be a viable anesthesia option in veterinary practice, specifically for perineal manipulations in horses. Furthermore, the absence of ataxia during or post-procedure bodes well for the comfort and safety of the animals treated with this anesthetic.

Cite This Article

APA
LeBlanc PH, Caron JP. (1990). Clinical use of epidural xylazine in the horse. Equine Vet J, 22(3), 180-181. https://doi.org/10.1111/j.2042-3306.1990.tb04243.x

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 22
Issue: 3
Pages: 180-181

Researcher Affiliations

LeBlanc, P H
  • Department of Large Animal Clinical Sciences, Michigan State University, East Lansing 48824.
Caron, J P

    MeSH Terms

    • Analgesia, Epidural / veterinary
    • Animals
    • Female
    • Horse Diseases / surgery
    • Horses / surgery
    • Perineum / surgery
    • Rectal Prolapse / surgery
    • Rectal Prolapse / veterinary
    • Rectum / injuries
    • Rectum / surgery
    • Thiazines
    • Urethra / surgery
    • Vagina / injuries
    • Vagina / surgery
    • Xylazine

    Citations

    This article has been cited 3 times.
    1. Vullo C, Tambella AM, Meligrana M, Catone G. Analgesic and Sedative Effects of Epidural Lidocaine-Xylazine in Elective Bilateral Laparoscopic Ovariectomy in Standing Mule Mares. Animals (Basel) 2021 Aug 17;11(8).
      doi: 10.3390/ani11082419pubmed: 34438877google scholar: lookup
    2. Caulkett N, Cribb PH, Duke T. Xylazine epidural analgesia for cesarian section in cattle. Can Vet J 1993 Nov;34(11):674-6.
      pubmed: 17424322
    3. Csik-Salmon J, Blais D, Vaillancourt D, Garon O, Bisaillon A. [Use of a mix of lidocaine and butorphanol as a caudal epidural anesthesia in a mare]. Can J Vet Res 1996 Oct;60(4):288-95.
      pubmed: 9026402