Clinical use of epidural xylazine in the horse.
- Journal Article
Summary
This research article explores the use of epidural xylazine, a form of anaesthesia, in horses for various perineal procedures, with findings indicating that it provides lasting and sufficient pain relief without causing unsteady movement in the animals.
Methodology and Procedures
The study involved administering xylazine into the epidural space of nine horses. Using this anesthetic was meant to facilitate various perineal manipulations in the horses. The researchers considered procedures like:
- Rectovaginal laceration repair
- Replacement of a prolapsed rectum
- Urethral extension
Findings and Results
The researchers found that the epidural xylazine provided enough caudal analgesia (pain relief in the lower part of the body) for the horses to undergo all the aforementioned procedures. They noticed that a single injection of epidural xylazine, with dosage varying from 0.17 to 0.22 mg/kg bodyweight, could provide analgesia for at least 3.5 hours. Importantly, no horses displayed any signs of ataxia (lack of muscle control or coordination of voluntary movements) both during and after the treatment.
Conclusions
The trial concluded that xylazine, when administered into the epidural space of horses, provides prolonged regional analgesia. This level of analgesia was found to be sufficient for clinical use, indicating that xylazine could be a viable anesthesia option in veterinary practice, specifically for perineal manipulations in horses. Furthermore, the absence of ataxia during or post-procedure bodes well for the comfort and safety of the animals treated with this anesthetic.
Cite This Article
Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences, Michigan State University, East Lansing 48824.
MeSH Terms
- Analgesia, Epidural / veterinary
- Animals
- Female
- Horse Diseases / surgery
- Horses / surgery
- Perineum / surgery
- Rectal Prolapse / surgery
- Rectal Prolapse / veterinary
- Rectum / injuries
- Rectum / surgery
- Thiazines
- Urethra / surgery
- Vagina / injuries
- Vagina / surgery
- Xylazine
Citations
This article has been cited 3 times.- Vullo C, Tambella AM, Meligrana M, Catone G. Analgesic and Sedative Effects of Epidural Lidocaine-Xylazine in Elective Bilateral Laparoscopic Ovariectomy in Standing Mule Mares. Animals (Basel) 2021 Aug 17;11(8).
- Caulkett N, Cribb PH, Duke T. Xylazine epidural analgesia for cesarian section in cattle. Can Vet J 1993 Nov;34(11):674-6.
- Csik-Salmon J, Blais D, Vaillancourt D, Garon O, Bisaillon A. [Use of a mix of lidocaine and butorphanol as a caudal epidural anesthesia in a mare]. Can J Vet Res 1996 Oct;60(4):288-95.