Common lesions of the distal end of the third metacarpal/metatarsal bone in racehorse catastrophic breakdown injuries.
Abstract: Equine catastrophic skeletal breakdown injury is a serious issue within the racing industry, given the impact on equine and human health. The metacarpo- and metatarso-phalangeal (fetlock) joints are common sites of catastrophic injury. However, lesions involving articular cartilage, subchondral bone, and synovium are commonly identified within the fetlock of the contralateral limb; hence, it is imperative that lesions in both limbs are evaluated and characterized during postmortem examination. Bone and articular cartilage changes typically occur in specific locations, related to cyclic fetlock load and overextension during high-speed exercise. Associations between preexisting degenerative fetlock lesions and catastrophic injury are a focus of continued research. These lesions often occur because of adaptive failure related to cumulative damage. Further investigation of these lesions is imperative to determine their impact on equine performance or injury. Ultimately, consistent documentation of catastrophic versus non-catastrophic osteochondral lesions provided by pathologists, in the context of training history, diagnostic imaging, and the presence or absence of catastrophic injury, will contribute to further understanding of skeletal responses associated with catastrophic failure.
Publication Date: 2017-07-07 PubMed ID: 28681688DOI: 10.1177/1040638717717948Google Scholar: Lookup
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- Journal Article
Summary
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The research article discusses the common lesions found in the lower part of the third metacarpal/metatarsal bone suffered by racehorses due to catastrophic breakdown injuries, the factors contributing to such injuries and the importance of detailed postmortem examinations in improving our understanding of equine injuries and performance.
Overview of Racehorse Catastrophic Breakdown Injuries
- The article emphasizes the significance of skeletal breakdown injuries among racehorses, shedding light on its implications for equine and human health. Such injuries often involve the metacarpo- and metatarso-phalangeal joints, more commonly known as fetlock joints.
- These joints bear the brunt of the horse’s weight during high-speed movement and are therefore highly susceptible to injury due to overextension.
Specific Lesions Related to Catastrophic Injuries
- Lesions are often detected in the synovium, subchondral bone, and articular cartilage within the fetlock of the contralateral limb of the horse. These specific locations are primarily related to the cyclical load on the fetlock during strenuous exercise.
- Further, the research highlights that these lesions often result from adaptive failure due to the cumulative damage that the horses’ bodies are unable to repair effectively.
Association between Degenerative Fetlock Lesions and Catastrophic Injuries
- Existing degenerative conditions of the fetlock can lead to these catastrophic injuries. Hence, the study aims to solidify the link between preexisting degenerative fetlock lesions and catastrophic injury.
The Importance of Postmortem Examination
- Comprehensive postmortem examinations are essential and should examine both limbs to accurately identify and characterize lesions. This study highlights the need for further investigation to gauge the impact of these lesions on equine performance and injury.
Impact of Consistent Documentation
- The researchers urge pathologists to consistently document lesions that culminate in both catastrophic and non-catastrophic injuries. They believe that such documentation, along with an understanding of a horse’s training history, diagnostic imaging, and data on catastrophic injury, can greatly contribute to a deeper understanding of these fatal skeletal failures.
Cite This Article
APA
Janes JG, Kennedy LA, Garrett KS, Engiles JB.
(2017).
Common lesions of the distal end of the third metacarpal/metatarsal bone in racehorse catastrophic breakdown injuries.
J Vet Diagn Invest, 29(4), 431-436.
https://doi.org/10.1177/1040638717717948 Publication
Researcher Affiliations
- Departments of Veterinary Science and Veterinary Diagnostic Laboratory, University of Kentucky, Lexington, KY (Janes, Kennedy).
- Rood and Riddle Equine Hospital, Lexington, KY (Garrett).
- Departments of Pathobiology and Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, PA (Engiles).
- Departments of Veterinary Science and Veterinary Diagnostic Laboratory, University of Kentucky, Lexington, KY (Janes, Kennedy).
- Rood and Riddle Equine Hospital, Lexington, KY (Garrett).
- Departments of Pathobiology and Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, PA (Engiles).
- Departments of Veterinary Science and Veterinary Diagnostic Laboratory, University of Kentucky, Lexington, KY (Janes, Kennedy).
- Rood and Riddle Equine Hospital, Lexington, KY (Garrett).
- Departments of Pathobiology and Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, PA (Engiles).
- Departments of Veterinary Science and Veterinary Diagnostic Laboratory, University of Kentucky, Lexington, KY (Janes, Kennedy).
- Rood and Riddle Equine Hospital, Lexington, KY (Garrett).
- Departments of Pathobiology and Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, PA (Engiles).
MeSH Terms
- Animals
- Fractures, Bone / pathology
- Fractures, Bone / veterinary
- Horse Diseases / pathology
- Horses
- Humans
- Metacarpal Bones / pathology
- Metatarsal Bones / pathology
Citations
This article has been cited 4 times.- Hill EW, Stoffel MA, McGivney BA, MacHugh DE, Pemberton JM. Inbreeding depression and the probability of racing in the Thoroughbred horse. Proc Biol Sci 2022 Jun 29;289(1977):20220487.
- Johnston GCA, Ahern BJ, Palmieri C, Young AC. Imaging and Gross Pathological Appearance of Changes in the Parasagittal Grooves of Thoroughbred Racehorses. Animals (Basel) 2021 Nov 24;11(12).
- Mazzotti E, Teti G, Falconi M, Chiarini F, Barboni B, Mazzotti A, Muttini A. Age-Related Alterations Affecting the Chondrogenic Differentiation of Synovial Fluid Mesenchymal Stromal Cells in an Equine Model. Cells 2019 Sep 20;8(10).
- Bellone RR, Ocampo NR, Hughes SS, Le V, Arthur R, Finno CJ, Penedo MCT. Warmblood fragile foal syndrome type 1 mutation (PLOD1 c.2032G>A) is not associated with catastrophic breakdown and has a low allele frequency in the Thoroughbred breed. Equine Vet J 2020 May;52(3):411-414.
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